SOLICITATION NOTICE
66 -- Reagent Kits for the Methylation Studies of Gynecological Cancers
- Notice Date
- 8/5/2013
- Notice Type
- Presolicitation
- NAICS
- 325413
— In-Vitro Diagnostic Substance Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- NCI-130099-HN
- Archive Date
- 8/20/2013
- Point of Contact
- Huy Nguyen, Phone: 2402765570, Seena Ninan, Phone: 240-276-5419
- E-Mail Address
-
anh-huy.nguyen@nih.gov, ninans@mail.nih.gov
(anh-huy.nguyen@nih.gov, ninans@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Description: The National Cancer Institute (NCI), Division of Cancer Epidemiology & Genetics (DCEG) plans to procure on a sole source basis with Illumina Inc, reagent kits required to continue the methylation studies of gynecological cancers The products herein are being procured in accordance with the simplified acquisition procedures as authorized by FAR Part 13.106-1(b)(2). The North American Industry Classification System code is 325413 and the small business standard is 500 employees. Only one (1) award will be made as a result of this solicitation. This will be awarded as a Firm Fixed Price (FFP) type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. The DCEG conducts methylation studies of gynecological cancers. Specifically, the DCEG studies genome-wide gene methylation in gynecological cancers and normal tissues to identify important carcinogenic pathways and possible biomarkers for risk assessment and early detection. DNA methylation at specific genes has been widely recognized as an alternative mechanism of tumor suppressor gene inactivation. A number of other genes have been described to be methylated in gynecological cancers, suggesting that methylation of some of these genes may occur at precancerous stages and drive carcinogenesis. DNA methylation is increasingly being evaluated as a biomarker. Methylated DNA is a stable analyte that can be measured from a wide range of biospecimens. The Illumina Infinium methylation platform is the most widely used large-scale methylation platform. The assay has been used in the NCI-funded The Cancer Genome Atlas (TCGA) efforts of gynecological cancers. The NCI is currently using the platform to analyze methylation in gynecological cancers. The NCI is extending the work and needs to be able to pool and combine the methylation data from the ongoing effort, the planned effort, and TCGA. Thus, it is important that the results are generated on the same platform. Further, only the Illumina Infinium platform has been validated for paraffin-embedded tissues and provides dedicated reagents to process this specimen type. Contractor Requirements: •Four (4) Illumina InfiniumHD FFPE Restore Kit (#WG-321-1002) •One (1) Illumina Human Methylation 450 DNA Analysis Bead Chip Kit (96 samples) (#WG-314-1002) Delivery: •Within twelve (12) months from the date of award. This is not a solicitation for competitive quotations. However, if any interested party, particularly small businesses, believe they can meet the above requirement, they may submit a statement of capabilities via fax or email. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. The capability statement must be received in the NCI contracting office on or before 4:00 PM EST on August 19, 2013. All questions must be in writing and can be faxed (240)-276-5399 or emailed to Anh-Huy Nguyen, Contract Specialist at anh-huy.nguyen@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) www.sam.gov. No collect calls will be accepted. Please reference solicitation number NCI-130099-HN on all correspondences.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/NCI-130099-HN/listing.html)
- Record
- SN03137845-W 20130807/130805235110-7080dfd1e7ec200bde76cdd8d846f986 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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