SOLICITATION NOTICE
66 -- MSM 400 Semi-Automatic Yeast Dissection Microscope System
- Notice Date
- 8/8/2013
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 1050, Frederick, Maryland, 21702, United States
- ZIP Code
- 21702
- Solicitation Number
- NCI-130102-TK
- Archive Date
- 9/7/2013
- Point of Contact
- Tiffany D. Kittrell, Phone: 2402765434
- E-Mail Address
-
Tiffany.kittrell@nih.gov
(Tiffany.kittrell@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Title: MSM 400 Semi-Automatic Yeast Dissection Microscope System Document Type: Pre-solicitation Solicitation Number: NCI-130102-TK Proposed Posted Date: August 6, 2013 Proposed Response Date: August 23, 201311AM EST Classification Code: 66 – Instruments & Laboratory Equipment NAICS Code: 334516 Small Business Size Standard: 500 Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room1E141, Bethesda, MD 20892 USA Description: The National Cancer Institute (NCI), The Laboratory of Biochemistry and Molecular Biology (LBMB) plans to procure on a sole source bases with Singer Instruments Company at Watchet, Somerset, TA230RE, United Kingdom for a for a MSM 400 Semi-Automatic Yeast Dissection Microscope System. The products herein are being procured in accordance with the simplified acquisition procedures as authorized by FAR Part 13.106-1 (b) (1). The North American Industry Classification System Code is 334516 and the business size standard in 500. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined that there is no opportunity to acquire green products or services under this procurement. Delivery shall be made within 4 weeks of contract award. The Laboratory of Biochemistry and Molecular Biology (LBMB) plans to procure on a sole source basis the MSM 400 Semi-Automatic Yeast Dissection microscope system manufactured by Singer Instruments to be used in conducting research into the underlying mechanisms of chromosome biology, including heterochromatin formation, chromosome segregation, chromosome organization, and telomere maintenance. This will allow NCI to discover the causative effect of defects in these fundamental processes, in particular as they pertain to the initiation of cancer cell states. Laboratories within LBMB investigate many aspects of chromosome biology, including heterochromatin formation, chromosome segregation, regulation of genome stability, and maintenance of telomeres. The laboratories study how chromosomes are accurately segregated, how they are organized, how compacted domains are formed, how gene expression patterns are regulated, and how structure contributes to the maintenance of genome stability. Particularly relevant to this acquisition is our use of the fission yeast model system, Saccharomyces pombe. Fission yeast provides a powerful model system with which to explore questions related to heterochromatin and telomere biology. In addition to the powerful genetic analysis available with the yeast system, S. pombe contains the basic machinery required for heterochromatin and telemore establishment, which is conserved in higher eukaryotes. This dissection microscope system will be used by members of LBMB for dissecting fungal spores to perform genetic analyses and strain constructions. This technique, called tetrad dissection, allows the analysis of gene function by the creation of mutant strains, as well as the genetic manipulation of the S. pombe genome to create useful strains for a variety of experiments to probe heterochromatin and telomere biology. The MSM 400 Semi-Automatic Yeast Dissection microscope system possesses the following salient characteristics: · Computer controlled, motorized platform for semi-automatic yeast spore dissection; Dissections can be performed through the eyepieces or by viewing the computer monitor; external image monitor is vital for teaching lab personnel the dissection technique · Automatic memory storage of cell placement positions for rapid re-localization to any point on an array · Micro Zapper, an electronically controlled device used for easy separation of spores, is used to vibrate the dissecting needle · Ability to create programs for automation of repetitive tasks · Digital CMOS camera for image capture of cells; ability to store and export images This is not a solicitation for competitive quotations. However, if any interested party, especially a small business, believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI Office of Acquisitions on or before 11:00 AM EST on August 23, 2013. Electronic capability statements will be accepted (i.e. email or fax). An original and one copy must be sent to the NCI Office of Acquisitions at the address stated above. All questions must be in writing and can be faxed to (240) -276-5399 or emailed to Tiffany Kittrell, Contract Specialist, at Tiffany.kittrell@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) www.sam.gov. No collect calls will be accepted. Please reference solicitation number NCI-­­­­­130102-TK on all correspondence.
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- SN03142082-W 20130810/130808235350-b6c151c323958f56f1bb421a030e543d (fbodaily.com)
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