SOLICITATION NOTICE
66 -- the purchase of a TI-U Eclipse Nikon microscope, along with a high NA (1.2) water objective, LED light source, 3d motorized stage and precision 3d piezo stage, an emCCD high quantum efficiency camera, and various microscope parts
- Notice Date
- 9/5/2013
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- NCI-130165-EB
- Archive Date
- 9/26/2013
- Point of Contact
- Erin M. Breedlove, Phone: 2402765387, Seena Ninan, Phone: 240-276-5419
- E-Mail Address
-
breeerin@mail.nih.gov, ninans@mail.nih.gov
(breeerin@mail.nih.gov, ninans@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E136, Bethesda, MD 20892, UNITED STATES Description The National Cancer Institute (NCI), Center for Cancer Research (CCR), Lab of Cell Biology plans to procure on a sole source basis the purchase of a TI-U Eclipse Nikon microscope, along with a high NA (1.2) water objective, LED light source, 3d motorized stage and precision 3d piezo stage, an emCCD high quantum efficiency camera, and various microscope parts from Nikon Instrument Inc. 336 South Service Road, Melville, NY 11747. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. Delivery shall be within 16 weeks after award. It has been determined there are no opportunities to acquire green products or services for this procurement. Contractor shall furnish one TI-U Eclipse Nikon microscope, along with a high NA (1.2) water objective, LED light source, 3d motorized stage and precision 3d piezo stage, an emCCD high quantum efficiency camera, and various microscope parts. The Nikon wide-field microscope is needed to meet the demand for force application and measurement, environmental and cellular viscoelasticity measurement, and extended time lapse imaging. The system must provide high resolution; expanded fluorescence capability; speed and ease of use; and quality image capture, processing, and storage capabilities. In addition it must be highly modifiable as the optical trap is home built, based around this microscope as a stage. The Nikon TI-U Microscope with Scanning Stage and Environmental Chamber will best meet all of NCI's and LCB's specifications in one integrated system. The Ti-U microscope has the following unique features: Microscope: •Inverted Microscope stand with stable objective turret for high-resolution imaging. Extra-long infinity space allows for insertion of more optics and the coupling of multiple lasers into the microscope. •Motorized X,Y, Z stage with high accuracy and reproducibility. Stage will include joystick but be fully software integrated. (GSA) •High resolution piezo stage, allowing for nm level precision in placement and movement of the sample, necessary for trapping calibration. •Objectives must include equivalent to Plan Apo 1.2 NA water objective. •LED light source, for minimal noise (no fan) as vibrations are picked up at nm levels. •High stability filter cubes to minimize noise and vibration. •High quantum efficiency emCCD camera to detect low light imaging and fluorescence. Also must allow high-speed (msec) scale full frame imaging. •Highly modifiable microscope base to allow coupling of home built trapping optics to microscope. Features of high resolution, modifiable Nikon scope: •Easily modified and adapted to current use. Customizability is the highest priority for adapting this scope to a home built system. •Digital gain (noise free contrast enhancement prior to bit depth conversion).in addition to standard master gain. •Free selection of emission bands for detection, omitting secondary dichroics or emission filters. Must be possible to set the emission bands over laser lines and still have efficient laser blocking to obtain superior signal to noise with low light fluorescent samples. •1.2 NA water objective known to be able to handle high infrared laser power. This microscope system is known to work for the purpose to which it is being adapted. This is a HUGE advantage in using this system, as downtime and testing a new microscope, which can take years, will therefore not be necessary. •Real time electronics control offers more flexibility in managing image data in parallel WHILE ACQUIRING! Users can image process and review, not only previously collected images, but also the image data set currently being acquired without interfering with the image acquisition. Parallel image Acquisition and Analysis on the Platform is a requirement. •Optics are designed for high transmission and aberration free imaging for 350 - 1100 nm. Software Options: The emCCD camera comes with high quality imaging software, and Labview drivers, allowing computer control and high levels of customizability. Other Key Features: •Objective and beam path can handle high power 1064nm laser light (20 W/cm^2, continuous wave) •Microscope has large infinity-space for modification and laser coupling. •Microscope has large number of additional options for the addition of high-res Total Internal Reflection Microscopy, oil objectives, secondary light sources •Microscope is modifiable (machine-shop modifiable) for the addition of custom home-built features. •emCCD camera for high-gain, high-res, low light imaging. •Piezostage and motorized stage for high resolution, long distance positioning. •All hardware must have Labview drivers for software control. •High-stability, low vibration components. •High NA water condenser (with option for air and high- NA oil condenser). •Low noise, fanless light sources. The microscope will allow NCI to integrate concepts from molecular biophysics and cell biology to understand how cells and tissues sense and respond to their physical microenvironment and to exploit these principles for the design of effective therapeutics and cellular biotechnology. These microscopy studies will create a new understanding of how normal and cancer cells are affected by their micro-environments, leading to new cancer therapies and new concepts in understanding malignancy, metastasis, and drug resistance. This new setup will allow force measurement, viscoelasticity measurement, wide-field low light fluorescence and wide-field imaging. The Nikon objective, compatible with this scope, is necessary as it has been tested to handle the high-power (20 Watt 1064 nm) laser that will be put through it. The Nikon Ti-U microscope is the only known microscope with the capability to interchange parts, and modify the scope as necessary. NCI has used the scope as the base for an optical trapping setup, therefore using it again will minimize downtime, errors and other issues that would come with using a different microscope system. The system must also be upgraded relatively easily and inexpensively in the future to add new capabilities as needed. This notice is not a request for competitive quotation. However, if any interested party especially small businesses, believes it can meet the above requirement, it may submit a capability statement, proposal, or quotation, which shall be considered by the agency. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Capability statements must be received in the contracting office by 11 AM EST, on September 11, 2013. All responses and questions must be in writing and faxed 240-276-5399 or emailed to Erin Breedlove Contract Specialist via electronic mail at breeein@mail.nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: NCI-130165-EB on all correspondence.
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- Record
- SN03176614-W 20130907/130906000438-75e6f2c2df78e353984d8afba819b6fb (fbodaily.com)
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