SOURCES SOUGHT
A -- MEDICAL SCREENING TECHNOLOGIES
- Notice Date
- 1/10/2014
- Notice Type
- Sources Sought
- NAICS
- 621511
— Medical Laboratories
- Contracting Office
- NASA/Lyndon B. Johnson Space Center, Houston Texas, 77058-3696, Mail Code: BH
- ZIP Code
- 00000
- Solicitation Number
- NNJ14ZBH007L
- Response Due
- 4/11/2014
- Archive Date
- 1/10/2015
- Point of Contact
- Mark A. Dillard, Lead Partnership Development Office Integration, Phone 281-244-8460, Fax 281-483-4146, Email mark.a.dillard@nasa.gov - Dana Altmon-Cary, Contracting Officer, Phone 281-483-8228, Fax 281-483-4066, Email dana.altmon-cary-1@nasa.gov
- E-Mail Address
-
Mark A. Dillard
(mark.a.dillard@nasa.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC) is seeking parties interested in collaborative development and mature technologies required for NASAs future missions and to enhance life on Earth. JSC is looking to partner on the development of broadly applicable technologies as a means to accelerate technology development and strengthen commercialization of federally-funded research and development. Purpose: NASA JSC is seeking parties interested in co-developing technology associated with health screening and health status monitoring. These technologies address anticipated human medical conditions and individual susceptibilities to environmental stressors and disease. Screening technologies sought are to personalize in-flight medical planning and care, pharmacogenomics, radiation exposure-associated risks, and the development of capabilities for prevention, screening for risk factors, and radiation biomarkers for early diagnosis and effective treatment. Health indicators to be addressed include, but are not limited to: malignancies, cataracts, increased intracranial pressure (ICP), cardiovascular risks, bone loss, oxidative stress, renal stone formation, sleep disorders, anxiety/depression, susceptibility to radiation and elevated CO2 levels. Particular importance is given to radiation exposure-associated risks as mentioned above. It is anticipated that the medical screening technologies co-developed will be of great interest to doctors and hospitals that desire quick and accurate patient medical information. These technologies will also be of great interest to persons providing remote medical care to such places as underdeveloped countries and military field hospitals. The radiation screening technology will have great relevance to many industries. Technology: From the research and medical operational needs, these targeted conditions fall into seven categories: The first category is musculoskeletal injuries/traumas requiring high contrast high-resolution visualization of bone, muscle and connective tissues for the detection of injury to determine proper treatment. Gaps in this category include: Meeting two often-conflicting needs for the ability to take images within bony structures versus maintaining high contrast in the surrounding soft tissues. Inability to obtain images of fracture using spaceflight compatible hardware. Forward technology development aims should include improving the capability to penetrate both soft tissue and underlying bone to diagnose fractures. Additional capabilities should include the ability to provide contrast enhancement in connective tissues and develop quantitative techniques for measuring bone degradation, muscle atrophy, changes in the lumbar spine, and compartment syndrome during exploration missions. Further gap closure might necessitate developing compact, flight-qualified radiographic capabilities for projection (and potentially tomographic) imaging. The second category includes internal injuries/traumas, which require high resolution, high contrast imaging to identify fluid collections and to locate subtle, often occult, injury sites in the soft parenchymal and connective tissues and their associated vasculature. Forward technology development aims in this area include improving the capability to visualize soft tissue deeper within the abdomen in sites that are currently occult (e.g., the pancreas), and providing contrast enhancement among abdominal and thoracic tissues. Further gap closure might necessitate developing flight-qualified radiographic capabilities for projection (and especially tomographic) imaging. Imaging derived technologies may also provide capability for treatment of specific conditions such as renal colic and internal hemorrhage. Four categories of conditions including ear/nose/throat (ENT) pathologies, ophthalmic injuries/ pathologies, topical injuries/pathologies, and oral/dental pathologies, are more amenable to traditional optical imaging techniques for diagnosis. These conditions sometimes require high-resolution images for the detection of relatively small pathologies. Gaps in these areas include the need to address a wide variety of conditions and the need to obtain depth penetration in lesions. The final category, cardiovascular pathology, requires high resolution, high contrast dynamic imaging of the heart muscle anatomy, arterial and vascular condition and blood flow in all areas of the cardiovascular system. Gaps in this category include meeting the need to produce high-resolution images (sub-millimeter resolution) with high temporal fidelity. Generally, successful utilization of less intuitive imaging technologies by minimally trained personnel to ensure ease of use and interpretation is a challenge that must be addressed. R&D Status: Screening technologies to personalize in-flight medical planning and care include: - Pharmacogenomics; - Disease and therapeutic monitoring markers for better diagnosis and treatment; and - Genomic screening and health status markers (predictive and preventive value) Intellectual Property (IP): Below are some examples of applicable NASA Technologies: Isotopic biomarkers for rapid assessment of bone mineral balance in biomedical applications; Accurate and Rapid Test for diagnosis of Viral Infections of the Eye; and "On Orbit Immuno-based, Label-free, White Blood Cell Counting System with MicroElectroMechanical Sensor (MEMS) Technology (OILWBCS-MEMS). Detailed information for the above mentioned technologies furnished upon request. This co-development project may produce new IP that could be jointly owned by NASA and the partner or may become the property of the partner. This announcement is not to be construed as a Request for Proposal and is not a commitment by the government, nor will the government pay for any information provided. Since this is an Announcement, no evaluation letters or results will be issued to the respondents. Please submit the attached Statement of Interest Form to Mark Dillard To view all Co-Development and Partnering Opportunities with the NASA Johnson Space Center please visit our website http://1.usa.gov/1bL99AF
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