SOURCES SOUGHT
66 -- Brand Name or Equivalent, K2 Direct Electron Detector Camera for the National Cancer Institute (NCI), Center for Cancer Research (CCR) TF30 Polara High Resolution Electron Microscope
- Notice Date
- 1/17/2014
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- SS-N02RC46011-83
- Archive Date
- 2/15/2014
- Point of Contact
- Gwennifer K. Epps, Phone: 240-276-5445, Terry Galloway, Phone: 240-276-5384
- E-Mail Address
-
eppsg@mail.nih.gov, gallowaytl@mail.nih.gov
(eppsg@mail.nih.gov, gallowaytl@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Notice Number: SS-N02RC46011-83 Issued By: National Cancer Institute (NCI), Office of Acquisitions (OA) http://www.nci.nih.gov or http://rcb.cancer.gov/rcb-internet/ Key Dates: Capability Statement Due Date: January 31, 2014 by 4:00PM EST This Small Business Sources Sought Notice (SBSS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Cancer Institute (NCI). The purpose of this Sources Sought Notice is to identify qualified small business concerns including 8(a), HUBZone or Service-Disabled Veteran-owned business concerns that are interested in and capable of performing the work described herein. The NCI does not intend to award a contract on the basis of responses received nor otherwise pay for the preparation of any information submitted. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This requirement is assigned North American Industry Classification System (NAICS) code 334516 with a size standard of 500 employees is being considered. As a result of this Sources Sought Notice, the NCI may issue a Request for Quotation (RFQ) through FBO. THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NCI shall arise as a result of a response to this Sources Sought Notice or the NCI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The purpose of this acquisition is to purchase a: • K2 Summit system - Polara • K2 Summit Installation and Basic Operator Training - Polara • Gen3 Camera housing assembly and flange - Polara • Latitude Tomography Software The Laboratory of Cell Biology (LCB) studies the processing, transport, and metabolism of proteins and small molecules related to malignant transformation and multidrug resistance in cancer. NCI employ the techniques of cryo-electron tomography and cryo-electron microscopy for studying single particles as well as virus and bacteria. Samples that are plunge-frozen are transferred and imaged in the electron microscope while they are still frozen. The acquisition of the K2 Direct Electron Detector Camera will enhance the imaging quality of NCI's pre-existing high resolution cryo-electron microscopes: a TF30 Polara electron microscope, manufactured by FEI. The K2 is a direct detector camera, capable of operating in the counting mode that is designed to specifically enhance data quality with the use of high resolution cryo-electron microscopes by more efficiently detecting electrons and converting them to images. The installation of the K2 Summit direct detector cameras on NCI's electron microscopes will facilitate collection of data at resolutions thought to be unachievable previously. The salient characteristics of this instrument are as follows: 1. The direct detection camera must have a minimum of 3840 x 3840 pixels, with 14-bit digitization capable of running a full frame rate at 400 frames/second with 1x binning. 2. The camera must include a hardware-enabled real-time electron counting mode of operation. 3. The camera must be capable of operating in the real-time electron counting mode with at least 20 electrons / pixel / second dose rate and sensor read-out at 400 full frames/second. 4. The camera must include a hardware-enabled super-resolution mode of operation that provides a sub-pixel electron counting mode. 5. The camera must be capable of operating in the super-resolution electron counting mode with at least 20 electrons / pixel / second dose rate and sensor read-out at 400 full frames/second. 6. The camera must provide a field of view in the super-resolution mode of more than 7400 x 7400 pixels. 7. In super-resolution mode, the camera must provide DQE. 0.65 @ 0.15 Nyquist Frequency. 8. The detector must have a lifetime exceeding more than 5 billion electrons per pixel, and swap-out times will be < 1 hour. 9. The camera must be compatible with mounting below a GIF spectrometer, and all hardware for mounting to the TF30 Polara electron microscope (FEI). 10. Software will be provided for image acquisition and processing, and the user interface must include functions for aligning stacks of dose-fractionated, electron-counted images. 11. The camera must be capable of remote diagnostics as well as remote system control and operation for troubleshooting. The camera must also support remote software updates. 12. TEM air, water, and electronic interface hardware shall be included as standard. 13. Installation and on-site training must be provided. 14. The camera must be capable of running at operating voltages of up to 300KeV and must be seamlessly integrated for data collection with the TF30 Polara electron microscopes (FEI). How to Submit a Response: 1. Page Limitations: Interested qualified small business organizations should submit a tailored capability statement for this requirement not to exceed 10 single sided pages including all attachments, resumes, charts, etc. (single spaced, 12 point font minimum) that clearly details the ability to perform the requirements of the notice described above. All proprietary information should be marked as such. Responses should include a minimum of a two pages demonstrating experience over the past two years meeting the requirements of this notice. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferable placed under the eligible small business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. 2. Due Date: Capability statements are due no later than 4:00 a.m. EST on January 31, 2014. 3. Delivery Point: All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the unique specifications described herein. Written responses can be emailed to Gwennifer Epps Contracting Officer at ge50d@nih.gov or mailed to the address located under Point of Contact. All questions must be in writing and can be faxed to (240) 276-5399 or emailed. A determination by the Government not to compete this requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA), through sam.gov. No collect calls will be accepted. Please reference number SS-N02RC46011-83 on all correspondence. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, an RFQ may be published on FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/SS-N02RC46011-83/listing.html)
- Place of Performance
- Address: NCI, Bethesda, Maryland, 20982, United States
- Zip Code: 20982
- Zip Code: 20982
- Record
- SN03269946-W 20140119/140117233821-4e0611cb4b7ec96dfef85b4d61935306 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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