SOURCES SOUGHT
66 -- Sequencing System - Sources Sought Notification
- Notice Date
- 2/7/2014
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- FDA_14-223-SOL-1130170
- Archive Date
- 2/28/2014
- Point of Contact
- Yolanda T. Peer, Phone: 8705437479
- E-Mail Address
-
yolanda.peer@fda.hhs.gov
(yolanda.peer@fda.hhs.gov)
- Small Business Set-Aside
- N/A
- Description
- Sources Sought Notification for a Sequencing System THIS IS A SOURCES SOUGHT ANNOUNCEMENT, A MARKET SURVEY FOR WRITTEN INFORMATION ONLY. THIS IS NOT A SOLICITATION ANNOUNCEMENT FOR PROPOSALS AND NO CONTRACT WILL BE AWARDED FROM THIS ANNOUNCEMENT. NO REIMBURSEMENT WILL BE MADE FOR ANY COSTS ASSOCIATED WITH PROVIDING INFORMATION IN RESPONSE TO THIS ANNOUNCEMENT OR ANY FOLLOW-UP INFORMATION REQUESTS. NO TELEPHONE CALLS WILL BE ACCEPTED REQUESTING AN RFQ PACKAGE OR SOLICITATION. THERE IS NO RFQ PACKAGE OR SOLICITATION. IN ORDER TO PROTECT THE PROCUREMENT INTEGRITY OF ANY FUTURE PROCUREMENT, IF ANY, THAT MAY ARISE FROM THIS ANNOUNCEMENT, INFORMATION REGARDING THE TECHNICAL POINT OF CONTACT WILL NOT BE GIVEN AND NO APPOINTMENTS FOR PRESENTATIONS WILL BE MADE. The U.S. Food and Drug Administration (FDA), National Center for Toxicological Research (NCTR) has issued this sources sought announcement in order to determine if there are existing small business sources capable of providing a Sequencing System. If your firm is considered a small business source under North American Industry Classification System (NAICS) Code 334516 - Analytical Laboratory Instrument Manufacturing Small Business Size status: 500 employees, and believe that your firm would be able to provide the FDA with the system described below, please submit an email to Yolanda.peer@fda.hhs.gov. The vendor should include information about the company and demonstrate that it can meet all of the specifications. Background: The Food and Drug Administration (FDA)/National Center for Toxicological Research (NCTR) is required to perform epigenetic analysis to discover the biomarkers related to nonalcoholic steatohepatitis (NASH) in mice. The capability of the sequencing technology will enable the quantitative genomic (single nucleotide polymorphisms (SNPs) and mutations), epigenomic (deoxyribonucleic Acid (DNA) methylation and chromatin immunoprecipitation) and transcriptomocs (messenger ribonucleic acid (mRNA) and small ribonucleic acid (RNA) expression) analysis of the mouse liver samples. Specifications: • The sequencing system shall perform clonal amplification, sequencing, and data analysis (base calling, alignment, variant calling, and reporting). • The sequencing system shall be capable of generating up to > 30 million reads per single run. • The sequencing system shall generate up to 15 GB of high-quality sequencing data. • The sequencing system shall utilize light based sequencing technologies for high accuracy. • The sequencing system shall be able to sequence with high accuracy genomic regions with high or low (guanine-cytosine) GC content and poly-T genomic regions. • The sequencing system does not require emulsion polymerase chain reaction (PCR) for sample preparation. • The sequencing system shall have high quality score distributions, > 75% of bases with quotient (Q) scores greater than 30. • The sequencing system shall support read lengths up to 2 × 250 bp run and provide the ability to generate 475 bp reads on the same fragment. Place of Performance: FDA/National Center for Toxicological Research 3900 NCTR Road Jefferson, AR 72079 Responses to this sources sought shall unequivocally demonstrate that the respondent is regularly engaged in the manufacturing and/or sale of same or substantially similar systems. Though the target audience is small business manufacturers or small businesses capable of supplying U.S. made system of another small business manufacturer or producer, all interested parties may respond. At a minimum, responses shall include the following: Business name and bio, DUNS number, business address, business website, business size status (i.e., SB, VOSB, SDVOSB, HUBZone SB, SDB, WOSB, LB), point of contact name, mailing address (if different from business address), phone number and email address; [Provide this same information again if responding to provide a system manufactured by another firm. Past performance information for the manufacturer and/or sale of same or substantially similar system to include date of sale, description, dollar value, client name, client address, client contact name, client point of contact mailing address (if different from that provided for client), client point of contact phone number, client point of contact email address, and name of the manufacturer (to include DUNS number and size status) if not the respondent. Descriptive literature, brochures, marketing material, etc. detailing the nature of the system the responding firm is regularly engaged in manufacturing and/or selling. If applicable, identification of the firm's GSA Schedule contract(s) by Schedule number and SINs that are applicable to this potential requirement are also requested. If a large business, provide if subcontracting opportunities exist for small business concerns. The Government is not responsible for locating or securing any information, not identified in the response. Interested Contractors must respond with capability statements which are due in person, by postal mail or email to the point of contact listed below on or before February 13, 2014 by 13:00 hours (Central Time in Jefferson, Arkansas) at the Food and Drug Administration, Field Operations Branch, FDA|OO|OFBA|OAGS|DAP, Attn: Yolanda Peer, 3900 NCTR Road, HFT‐320, Bldg 50, Rm 420 Jefferson, AR 72079‐9502 or email yolanda.peer@fda.hhs.gov. Reference: FDA_14-223-SOL-1130170. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre‐solicitation synopsis and solicitation may be published in FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non‐proprietary technical information in any resultant solicitation(s). Additional Notes: If the stated requirements appear restrictive, please submit comments detailing the concern. Though this is not a request for quote, informational pricing for the system would be helpful.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/FDA_14-223-SOL-1130170/listing.html)
- Place of Performance
- Address: FDA/National Center for Toxicological Research, 3900 NCTR Road, Jefferson, Arkansas, 72079, United States
- Zip Code: 72079
- Zip Code: 72079
- Record
- SN03284492-W 20140209/140208000434-3c1ea78e50481489fa040d376174f3f0 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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