SOLICITATION NOTICE
J -- Bio-Rad Laboratories Digital PCR QX200 Droplet Reader
- Notice Date
- 6/30/2014
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- N02RC42559-83
- Archive Date
- 7/30/2014
- Point of Contact
- Gwennifer K. Epps, Phone: 240-276-5445, Terry Galloway, Phone: 240-276-5384
- E-Mail Address
-
eppsg@mail.nih.gov, gallowaytl@mail.nih.gov
(eppsg@mail.nih.gov, gallowaytl@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Cancer Institute (NCI), Center for Cancer Research (CCR), Molecular Diagnostics Laboratory (MDL) of the Laboratory of Pathology, plans to procure one digital droplet PCR QX-200 complete system and startup kit from, Bio-Rad, Life Science Research, 2000 Alfred Nobel Drive, Hercules, CA. 94547, USA. This process will be processed in accordance with simplified acquisitions procedures as stated in FAR Part 13 13.106-1(b)(1) and is exempt for the requirements of FAR Part 6. The North American Industry Classification System code is 334516, and the business size standard is 500 employees. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. The period of performance will be for two months only after award of the order. The Molecular Diagnostics Laboratory (MDL) of the Laboratory of Pathology performs molecular testing to assist in the diagnosis of a variety of cancers. The laboratory develops and performs tests that assist in pathologic diagnosis, predict prognosis and identify potential targets for rational personalized therapies. It is currently the only CLIA and College of American Pathology approved clinical laboratory within the NCI certified for performing molecular oncology testing on materials from NIH patients. The MDL laboratory has initiated a program to study circulating tumor DNA (ctDNA) to evaluate its use as a tumor specific marker. Preliminary studies in melanoma in the MDL have shown the enormous potential of ctDNA to assess treatment efficacy and predict response of tumor infiltrating lymphocytes in individual patients with melanoma. Using a non-digital high sensitivity allele-specific PCR technique that incorporates wild type allele suppression (targeting tumor specific mutant BRAF), NCI's preliminary data indicates that MDL can accurately predict: accuracy which patients will respond to tumor infiltrating lymphocyte (TIL) immunotherapy within 6-10 days by following the dynamic changes in serum mutant BRAF DNA. Currently it takes 1-2 months to determine whether patients are responding to TIL therapy. A sole source to Bio Rad laboratories is intended for this order; based on the fact NCI/MDP believes this system is the best platform currently available to fulfill its general requirements for the following reasons: 1) it is the most mature platform with 300 instruments in the field; 2) it is a high through-put platform with a maximal output of 300-400 tests per day; 3) it possesses an easy to use user interface essential for the development of Laboratory Developed clinical Tests (LDTs); and 4) it has a rapid analysis software. NCI believes it is extremely important to have this technology platform, as it will enable MDP to continue to develop assays and expertise to evaluate the use of these tumor specific nucleic acid based biomarker assays in NCI/NIH clinical trials. Note: One Bio-RAD Digital Droplet PCR QX-200 complete system and startup kit to include the following items: 1. One Bio-Rad Digital Droplet PCR QX-200 digital PCR reader 2. One Bio-Rad Digital Droplet Generator 3. One Automated Droplet Generator 4. One Laptop computer for ddPCR system 5. One PX1 PCR Plate Sealer 6. One Droplet Reader Oil 7. One C1000 Touch Cycler w/96W DP RM 8. DG8 Cartridge Gaskit, QX100/200 DG 9. ddPCR SMX PRBS nod UTP 500 (x2) 10. Drplet Generation Oil 11. QX200 EvaGreen ddPCR SMX (x2) 12. QX200 Drplet Generation Oil This is not a solicitation for competitive quotations. However, if any interested party, especially a small business believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI Office of Acquisitions on or before 11:00 AM EST on, July 15, 2014. No electronic capability statements will be accepted (i.e. email or fax); an original and one copy must be sent to the NCI Office of Acquisitions at the address stated above. All questions must be in writing and can be faxed (240) 276-5401 or emailed to Gwennifer Epps, Contracting Officer at ge50d@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA), through sam.gov. No collect calls will be accepted. Please reference solicitation number N02RC42559-83 on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/N02RC42559-83/listing.html)
- Place of Performance
- Address: 10 Center Drive, National Cancer Institute, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03410538-W 20140702/140701024534-1f3528b109f0029e88ace63da2f4d8c8 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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