SOURCES SOUGHT
66 -- Hybrid Mass Spectrometer with Triple Quadrupole
- Notice Date
- 8/7/2014
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- FDA-14-1138058-SS
- Archive Date
- 8/29/2014
- Point of Contact
- Tiffany R. Williamson,
- E-Mail Address
-
tiffany.williamson@fda.hhs.gov
(tiffany.williamson@fda.hhs.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- Notice to Small Businesses The purpose of this notice is to obtain information regarding the availability and capability of qualified small business concerns. The Food and Drug Administration intends to provide maximum practicable opportunities in its acquisitions to small businesses. The Food and Drug Administration (FDA) is conducting a market survey to assess the availability of small business firms as defined by NAICS code 334516 that has the capability to provide Hybrid Mass Spectrometer with Triple Quadrupole (Tandem Quadrupole) and Linear Ion Trap and a one (1) 12 month option period for preventative maintenance and service for each instrument. This notification is for market research purposes and does not constitute a commitment, implied or otherwise, that a procurement will be accomplished. FDA welcomes responses from all interested parties. FDA does not intend to make a selection decision or award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted of FDA's use of such information. Acknowledgment of receipt of responses will not be made, nor will respondents be notified of the outcome of the FDA's review of the information received. Additionally, the FDA does not intend to hold discussions concerning this sources sought with any interested parties. However, FDA reserves the right to contact vendors if additional information is required. Brand Name or Equal: This is a BRAND NAME OR EQUAL acquisition; in accordance with FAR 52.211-6, to be considered for award, offers of equal products must meet the salient physical, functional, or performance characteristics provided in the statement of requirements. In order to be considered an "equal" solution, any alternative solution proposed must be able to perform in strict accordance with the salient operational and technical features described below. Background The Food and Drug Administration (FDA), Atlanta Center for Nutrient Analysis (ACNA), Southeast Region Laboratory (SRL) requires a Hybrid Mass Spectrometer with Triple Quadrupole (Tandem Quadrupole) (UHPLC-MS/MS) and Linear Ion Trap instrument. The UHPLC-MS/MS must have the capability to interface with an Ultra High Performance/Pressure Liquid Chromatograph (UHPLC). This instrument will analyze micronutrients in complex food matrices, including water soluble vitamins, fat soluble vitamins, lipid related compounds, artificial sweeteners, and allergenic proteins. The UHPLC-MS/MS shall include a one year manufactured warranty and preventative maintenance service agreement for one (1) 12 month option period. Specific Tasks and Deliverables: The instrument (equipment) must meet or exceed the minimum requirements listed below. The Inductively Coupled Plasma Mass Spectrometry Hybrid Mass Spectrometer with Triple Quadrupole (Tandem Quadrupole) and Linear Ion Trap Instrument shall "meet or exceed" the following salient characteristics/specifications: • The system must include a computer, monitor, keyword, mouse and printer. • The system must include all software (with the latest update) necessary to operate the instrument and process (quantitatively and qualitatively) the raw data from the mass spec after the acquisition. • The system must include a source(s) for atmospheric pressure chemical ionization/electrospray ionization (APCI/ESI) mode, and additional ionization mode (i.e., APPI), if available. • The system must include nitrogen generator and a compressor for the generator (which meets the industry standards/norms). • The system must use nitrogen (standard for these types of mass spec instrument) as collision gas. • The system must have the capability of using the MS detector as triple quadupole and linear ion trap in tandem. • The system must have the following Scan mode: Q1 MS, Q3 MS, product ion, precursor ion, neutral loss or gain, and multiple reactions monitoring (MRM), timed/scheduled MRM and the Scan modes utilizing a linear ion trap includes enhanced mass (EMS), enhanced product ion (EPI), enhanced resolution (ER), MS3, MRM3, and other types utilizing QQQ and LIT simultaneously, etc. • The system must include an Ultra High Performance/Pressure Liquid Chromatograph (UHPLC) system for fast analysis with solvent selection capability of handling up to four different solvent lines). • The system must have a fast scanning rate (up to 20,000 Da/sec) to fully utilize chromatographic separations by UHPLC system. • The system must have a polarity switching speeds of 20 millisec (ms), a minimum MRM dwell time of 1 ms, and dynamic range of 5 orders of magnitude (minimum) • The system must have a mass range of 5 up to 2000 m/z. • The system must have a mass stability of 0.1 Da over 8 hours. • The system must be able to handle a flow rate range of 5 µL/min to 3 mL/min, a high- precision syringe pump and switching valve capability. • The ability of maintaining the temperature of UHPLC column compartment from 10 ~ about 90 OC. • The system ionization source must have maximum temperature of 750 OC for electrospray ionization. • The ionization source must have a technology (for example, IonDrive Turbo V source or equivalent) which improves ion production, ion focusing and ion transmission. • Must include installation qualification (IQ/OQ/PQ). The vendor must provide documentation of the qualification to the user upon installation. • Must provide all chemicals/solutions and accessories for instrument maintenance, calibration and qualification. • Must be LIMS-compatible. • A one-year manufacturer's warranty is required with the purchase and must include at a minimum: o Coverage on all non-consumable items and parts supplied including base instrument (LC and mass spec), computer and other accessories. o Unlimited on-site service visits within 48 hours of call, factory-certified replacement parts, engineer labor and travel costs, software updates and notifications. o Service must be performed by a certified and trained engineer. • Must include an introductory on-site initial training lasting up to 3 days for up to 5 ACNA analysts. • Must include (only the cost for) off-site training for two ACNA personnel. Training: The contractor must provide a three (3) day on-site training for 5 analysts at the delivery location listed below. The on-site training must include, but not limited to manual (paper or digital) of the equipment and basic functions, operation of the Hybrid Mass Spectrometer with Triple Quadrupole (Tandem Quadrupole) and Linear Ion Trap, hardware and software integration, generating reports, overview of the equipment, the functionality of the equipment, tuning and calibration. The contractor must provide off-site (at the manufacture training facility) training for 5 analysts for each location listed in the SOW. The tuition for the training must be included for the off-site training. The training must include, but not limited to manual (paper or digital) of the equipment and functions, operation of the the Hybrid Mass Spectrometer with Triple Quadrupole (Tandem Quadrupole) and Linear Ion Trap instrument, hardware and software integration, generating reports, basic interpretation, overview of the equipment, the functionality of the equipment, tuning and calibration. On-site training shall be conducted at the time of installation or scheduled no later than one (1) week after installation and successful qualification of the instrument. Training shall not be conducted no later than three (3) weeks after completed installation. Technical /Support Services: The contractor must provide one year manufacture warranty for all parts, labor, travel, technical, on-line, and telephone support service for a 12 month (one year) period after complete delivery, installation, and training at no additional cost to the government. The contractor shall provide full service support for the installed equipment, including but not limited to labor, parts, travel on-site support, telephone support, retesting and re-qualification of the unit, software updates and enhancements. The contractor must provide continuous online and telephone support for the instrument. The support services shall include, but not limited to trouble shooting, equipment maintenance and repair, and provide responses to operator questions. The contractor shall provide a three (3) day response time for all on-site service and repairs. All service reports shall be provided to the government point of contact within 5 business days of completion of the repair or service. Preventative Maintenance: The annual on-site preventative maintenance/service agreement shall include but not limited to the support of qualification and calibration service, cleaning of the instrument, software and hardware updates, technical, on-line/telephone support services, replacement of parts, labor, and travel in support of the instrument at the location. The preventative maintenance service will be listed as option periods on the contract. The preventative maintenance (PM) service will be for one (1) 12 month option period after the 12 month (one year) manufacture warranty is expunged. The contractor shall provide a services report to the government point of contact after completion of the annual PM services. Delivery Timeframe 90 days after receipt of award Delivery Location Southeast Regional Laboratory Food and Drug Administration 60 Eighth Street NE Atlanta, GA 30309 POC: TBA *Complete address and Point of contract shall be listed at the time of award. Unless otherwise specified, deliveries shall be made to the Delivery Point specified above, Monday through Friday (excluding Federal Holidays, see (PART 8) between the hours of 8:30 a.m. and 4:30 p.m. in accordance of the delivery location time zone (Eastern Time, Central Time, or Pacific Time). Supplies or services scheduled for delivery on a Federal holiday shall be made the next business day. The Contractor shall provide the FDA with one (1) week's scheduling notice prior to setup of the laboratory instrument and component parts. General Instructions Contractors that believe they possess the ability to provide the required equipment must submit documentation of their ability to meet each of the characteristics listed above to the Contracting Officer (i.e. brochure, information on equipment that meets specifications, etc.) The capability statement must also include the organization name, type of business, DUNS number, point of contact name/telephone number/email address, and applicable NAICS code. Capability statements that do not provide sufficient information for assessment will be considered non-responsive. When submitting the information, please reference the solicitation number FDA-14-1138058-SS. Responses must be submitted via email to Tiffany Williamson at Tiffany.Williamson@fda.hhs.gov by 12:00 pm on August 14, 2014.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/FDA-14-1138058-SS/listing.html)
- Place of Performance
- Address: Southeast Regional Laboratory, Food and Drug Administration, 60 Eighth Street NE, Atlanta, Georgia, 30309, United States
- Zip Code: 30309
- Zip Code: 30309
- Record
- SN03456527-W 20140809/140808000743-8fe6d494e82a8c99252b7894e95e8bf6 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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