SOLICITATION NOTICE
66 -- Tunable Resistive Pulse Sensor instrument for characterizing roles of exosomes in aging and neurodegenerative disease
- Notice Date
- 8/12/2014
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-CSS-14-551
- Archive Date
- 9/2/2014
- Point of Contact
- Hunter A. Tjugum, Phone: 301 435 8780, ,
- E-Mail Address
-
hunter.tjugum@nih.gov, NIDASSSAPurchaseRequ@mail.nih.gov
(hunter.tjugum@nih.gov, NIDASSSAPurchaseRequ@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-14-551 and the solicitation is issued as a Request For Quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. Any resultant purchase order resulting from this solicitation is not expected to exceed the Simplified Acquisition Threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-76, dated 25 JULY 2014. The associated NAICS code is 334516-Analytical Laboratory Instrument Manufacturing with an associated small business size standard of 500 employees. This requirement is released with no set-aside restrictions. DESCRIPTION Background: The National Institute on Aging (NIA), one of the 27 Institutes and Centers of NIH, leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. The Intramural Research Program (IRP) of the National Institute on Aging (NIA) provides a stimulating setting for a comprehensive effort to understand aging through multidisciplinary investigator-initiated research, in this regard. The Laboratory of Neurogenetics (LN) at NIA, IRP is tasked with finding the genes and gene mutations that cause or contribute to neurological disease. These discoveries allow the transfer of those genes and mutations into cells in order to make a model which helps the field to better understand disease processes. As more is understood about the disease progression, additional models can be used to test therapies. A primary focus of the Laboratory of Neurosciences is to study basic mechanisms and elucidate potential therapies directed to neurodegenerative diseases including Alzheimer's disease, Parkinson's disease and Amyotrophic Lateral sclerosis. There is a growing body of scientific evidence describing the role exosomes in cell/cell signaling events in normal and disease states, including neurodegenerative diseases. Product Description: The NIA, IRP, LN has a requirement for a laboratory instrument that can characterize exosome preparation for use in in-vitro and in-vivo experiments to help achieve an understanding of neurobiology and neurogenerative disease processes. Required instrument must be functionally capable for analysis, characterization and timely purification of exosomes in existing research. The essential government feature that this requirement needs to achieve is obtaining a tunable resistive pulse sensor (TRPS) type of device, which accurately characterizes and differentiates between exosomes particles in the size range required (i.e. 50 to 200 nm particle size). The subject instrument needs to achieve a method capable of distinguishing between distinct particle size groups within the range desired and specified herein. All deliveries must be made FOB destination to 251 Bayview Blvd, Baltimore, MD, 21224. INSTRUCTIONS TO OFFERORS Offerors may respond with a quotation indicating their ability to provide the technical requirements stated in this solicitation. Pricing proposals shall indicate the unit price of the supplies specified in this solicitation, including shipping cost and estimated time of delivery after receipt of order. Responses will be evaluated based on contractor's ability to fulfill the technical requirements stated in this notice and on ability to deliver required supplies. Responses may also include any additional accessories, calibration, consumables or starter packs, or applicable software or warranty considerations. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Responses to this RFQ must not exceed 15 pages in length and be submitted in Microsoft Word or searchable PDF format in a font size of 11 or 12 point and font type of Arial or Times New Romans. Margins must be 1-inch wide (top, bottom, left, and right). Responses must references this solicitation number and include the name of the contractor. Pages in excess of the specified page limit will not be considered or evaluated. The following FAR provisions shall apply to this solicitation: 52.212-1, Instructions to Offerors--Commercial Items, 52.212-2, Evaluation--Commercial Items. Evaluation factors that will be used to evaluate the offer most advantageous to the Government, price and other factors considered, include ability to meet the technical requirements stated in this pre-solicitation and on basis of best value to the government. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer. The Clause at 52.212-4, Contract Terms and Conditions Commercial Items, applies to this acquisition and the Clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received no later than the response deadline indicated on August 18, 2014, 12:00 pm Eastern time. Late responses will not be accepted. All responses must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-14-551. Responses may be submitted electronically to Hunter.Tjugum@nih.gov and to NIDASSSAPurchaseRequ@mail.nih.gov. Fax responses will be accepted at (301) 480-1358. For information regarding this solicitation, contact Hunter Tjugum by email at hunter.tjugum@nih.gov or by phone at (301) 435-8780.
- Web Link
-
FBO.gov Permalink
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- Record
- SN03461531-W 20140814/140813022101-0e14eda4b67eb206e6a402918894308c (fbodaily.com)
- Source
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