SOLICITATION NOTICE
66 -- Ethanol Inhalation system
- Notice Date
- 8/18/2014
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA(SSSA)-NOI-14-356
- Archive Date
- 9/16/2014
- Point of Contact
- Farrin Stanton,
- E-Mail Address
-
farrin.stanton@nih.gov
(farrin.stanton@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION This is a pre-solicitation non-competitive (notice of intent) synopsis to award a contract without providing for full or open competition (including brand-name). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR PROPOSAL. A SOLICITATION WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Institute on Drug Abuse (NIDA), Consolidated Station Support and Simplified Acquisitions (CSS/SA) Branch intends to negotiate and award a purchase order to La Jolla Alcohol Research, Inc for 3 Custom Inhalation chamber systems without providing for full and open competition (including brand-name). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 500 Employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-72 dated January 30,2014. This acquisition is for a commercial item or service and is conducted under the procedures as prescribed in FAR subpart 15-Contracting by Negotiation. This acquisition is expected to exceed the simplified acquisition threshold. STATUTORY AUTHORITY This acquisition is conducted under the authority of the authority of FAR Subpart 15.002-a. DESCRIPTION OF REQUIREMENT Purpose and Objectives Initially, drug intake is motivated by the pleasant drug effects (positive reinforcement). In the transition to drug dependence, the brain stress systems become sensitized and drug intake is motivated by negative reinforcement mechanisms in which the drug is taken to relief negative emotional states (e.g., anxiety, depression, dysphoria, pain). Therefore, understanding the processes mediating the transition from positive to negative reinforcement in the transition to dependence is critical to develop new methods of prevention, diagnosis and treatment of drug dependence. The vapor chambers setup must be unique to allow us to reliably induce alcohol dependence, which would not be possible with voluntary intake or exposure to low alcohol levels. The blood alcohol levels can be precisely monitored and controlled so that animals are healthy and active. The drug vapor chambers should allow for vaporization of methamphetamine, cocaine, THC, nicotine, etc. The levels of intoxication must also be precisely measured and maintained in a safe range. A practical application of drug vapor chambers is modeling nicotine abuse and dependence. The levels of nicotine exposure have to be controlled in a way to model second hand smoking, mild, moderate and heavy smoking. These features make the alcohol and drug vapor chambers unique to producing different levels of drug intoxication and withdrawal and allowing us to the study different phases of the addiction process for different drugs of abuse. This is important because the burden of disease and disability caused by alcohol, tobacco and other drugs of abuse is enormous. The design of the inhalation chambers have to be designed to perfection to meet the lab needs. This equipment will be used on a daily basis and will be the main equipment in the lab along with operant chambers. Period of Performance Delivery is required within 3 months after receipt of award. A firm fixed price purchase order is contemplated. Project Description The Contractor must be able to provide the following: The Custom Inhalation Chamber System must consist of: Custom ethanol inhalation system with six oversized, separate cages that can accommodate three 700 gram rats per chamber, maintaining AALAS space regulations.60 cages included. 100 custom 16 ounce water bottles with caps and sipper tubes included. Custom e-Vape Chamber System. Custom e-Vape system for five addictive inhalants. Includes six standard rat chambers. 24 Cage bottoms included.6 Cage tops included. The Behavioral Neuropharmacology Section uses alcohol and drug inhalation chambers to produce robust models of alcohol and drug dependence. The requirements are: • These chambers must allow us to very precisely control the concentration of alcohol or drug in the air to produce different levels of alcohol/drug exposure to induce a wide range of biological changes to be systematically studied. • Importantly, they must allow intoxication levels to be tightly controlled to preserve animal health. • Must reliably induce alcohol dependence, which would not be possible with voluntary intake or exposure to low alcohol levels. The blood alcohol levels can be precisely monitored and controlled so that animals are healthy and active. • The alcohol and drug inhalation chambers must have a double-chamber containment system that guarantee that the experimenter is safe of any hazardous vapor exposure at all time. Therefore, even if the experimenter forget to close the rat chamber or do it improperly resulting in air leakage the double containment will ensure that the room where the system is, is not contaminated • The alcohol and drug inhalation chambers must have a double exhaust system that provide negative pressure inside the first containment chamber so that no vapor escape the system when the doors are open. Guaranteeing again the safety of the experimenter. Other commercially available system have only 1 exhaust without containment chamber with negative pressure. • Must have carbon activated charcoal in the exhaust line to scrub drug vapors before going into house exhaust • Each chamber must be upgradable to do exposure to electronic cigarettes and methamphetamine, cocaine, THC and heroin vapor • Each chamber must have an integrated sampling system to monitor the concentration of vapor in the air. • Must be IACUC and AAALAC certified. 3 each - Custom Inhalation Chamber System Custom ethanol inhalation system with six oversized, separatecages that can accommodate three 700 gram rats per chamber, maintaining AALAS space regulations. 60 cages included. 100 custom 16 ounce water bottles with caps and sipper tubes included. 1 each - Custom e-Vape Chamber System Custon e-Vape system for five addictive inhalants. Includes six standard rat chambers. 24 Cage bottoms included. 6 Cage tops included 6 Cage grids included CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, LaJolla Alcohol Research, Inc. is capable of meeting the needs of this requirement due to data standardization requirements. The National Institute on Drug Abuse (NIDA) hase extensively used the alcohol and drug inhalation chambers form La Jolla Alcohol Research, Inc. to produce robust models of alcohol and durg dependence. The specific unique qualifications of the La Jolla system are, it has a double-chamber containment system, a double exhaust system, carbon activated charcoal in the exhaust line, allows other drug vapor exposure, and monitors air concentration. All these specifications help to ensure more precise controlled testing. The system is also IACUC and AAALAC certified. The intended source is: La Jolla Alcohol Research, Inc. POB 13397 La Jolla, CA 92039 ATTN: Bette Cessna CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by the closing date and time of this announcement and must reference the solicitation number. Responses may be submitted electronically to Farrin Stanton, Contract Specialist, at Farrin.Stanton@nih.gov. US Mail and Fax responses will not be accepted.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA(SSSA)-NOI-14-356/listing.html)
- Place of Performance
- Address: National Institute on Drug Abuse, 6001 Executive Blvd., Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03469801-W 20140820/140819000313-6fcc0b604a9d5ded32a35e1266625ef2 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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