SOLICITATION NOTICE
66 -- Digital PCR
- Notice Date
- 9/11/2014
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Commerce, National Institute of Standards and Technology (NIST), Acquisition Management Division, 100 Bureau Drive, Building 301, Room B130, Gaithersburg, Maryland, 20899-1410, United States
- ZIP Code
- 20899-1410
- Solicitation Number
- SB1341-14-RQ-0773
- Archive Date
- 10/3/2014
- Point of Contact
- Erik Frycklund, Phone: 3019756176
- E-Mail Address
-
erik.frycklund@nist.gov
(erik.frycklund@nist.gov)
- Small Business Set-Aside
- N/A
- Description
- THIS IS A COMBINED SYNOPSIS/SOLICITATION FOR COMMERCIAL ITEMS PREPARED IN ACCORDANCE WITH THE FORMAT IN FAR SUBPART 12.6-STREAMLINED PROCEDURES FOR EVALUATION AND SOLICITATION FOR COMMERCIAL ITEMS-AS SUPPLEMENTED WITH ADDITIONAL INFORMATION INCLUDED IN THIS NOTICE. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION; QUOTATIONS ARE BEING REQUESTED, AND A WRITTEN SOLICITATION DOCUMENT WILL NOT BE ISSUED. This solicitation is a Request for Quotations (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-76 effective July 25, 2014. The associated North American Industrial Classification System (NAICS) code for this procurement is 334516 with a small business size standard of 500 employees. This acquisition will be competed using full and open competition. This is not a small business set-aside. Simplified acquisition procedures will be utilized. The National Institute of Standards and Technology's Applied Genetics Group in the Biochemical Science Division at NIST is developing quantitative DNA-based Standard Reference Materials (SRMs) for clinical customers. The Applied Genetics Group is interested in adding intercalating dye detection capabilities to digital PCR. To keep up with changing technologies acquiring a system capable of intercalating dye and creates ≥20,000 individual PCR reactions per sample. The Applied Genetics Group both needs to add the ability to analyze dPCR products with an intercalating dye in a system that produces ≥20,000 individual PCR reactions per sample. Intercalating DNA dyes allow dPCR to be completed without the use of hydrolysis probes, which are a significant cost of the PCR assay. Using intercalating dye detection will allow for some unique multiplexing capabilities and simultaneously stop using hydrolysis probes (aka TaqMan probes), which will reduce operating costs and allow for additional primer pair analysis. THIS IS A BRAND NAME ONLY REQUIREMENT. QUOTERS MUST PROVDE THE REQUIRED BRAND NAME PRODUCT. The brand name justification follows. The Applied Genetics Group is currently working on Standard Reference Materials (SRMs) using an existing NIST owned Bio-Rad QX100. NIST requires this equipment to be updated to a newer model for faster dPCR processing yet assuring historic validation of existing SRMs. Deviating from the existing BioRad platform could result in a lapse production and study stability could be lost. The transition to the QX200 will require a short run verification and validation of the system. Given historic validation programs up to six months delay may be needed to fully validate any other PCR system. The Bio-Rad QX200 main source of bias comes from emulsion generation and the QX100 and QX200 use the same droplet generator. Responsible quoters shall provide pricing for all of the following line items. Both new and factory certified refurbished instruments will be considered for award. The factory certified refurbished instrument must meet the manufacturer's original specification. LINE ITEM 0001 - Quantity 1 each QX200 Droplet Reader manufactured by Bio-Rad. Prior to final acceptance by the Government, digital PCR system shall meet all of the following required specifications. • Must be capable of creating ≥20,000 individual PCR reactions per sample • Must be the latest available model; obsolete models will not be considered. • Must be able to analyze individual PCR reactions that used intercalating dye (e.g. EvaGreen®) PCR chemistry and hydrolysis (aka TaqMan® chemistry). • Must include the latest available software upgrade that is able to analyze both hydrolysis and intercalating PCR chemistries • Must be compatible with the QX100 Droplet Maker • Must include operations and maintenance manual for the instrument Based on budgetary restrictions, the Government strongly prefers, but does not require, that the Contractor accept the following equipment for trade-in credit: Manufacturer: Bio-Rad Model: QX100 Droplet Reader Serial Number: DR-10256 NIST Property Number: N102121 All equipment is in good condition and is currently functioning to manufacturer's specifications. LINE ITEM 0002: INSTALLATION The Contractor shall install the instrument in Building 227, Room B225, at NIST Gaithersburg, MD. Installation shall include, at a minimum, uncrating/unpackaging of all equipment, set-up and hook-up of all equipment, start-up, demonstration of specifications, and removal of all trash. Instrument will operate to manufacturer's specifications upon installation. Installation will take place during normal business hours, between 8:30 am and 5:00 pm Eastern Time, Monday through Friday except Federal Holidays, and will be coordinated with the NIST Technical Point of Contact (TPOC). Installation is to occur within 30 days of award. LINE ITEM 0003: TRAINING The Contractor shall include at least two (2) hours of training at NIST for up to 2 NIST personnel covering normal operation, troubleshooting, and routine maintenance. Training will be provided during normal business hours, between 8:30am and 5:00pm Eastern Time, Monday through Friday, except Federal Holidays, and will be coordinated with the NIST Technical Point of Contact (TPOC) to ensure maximum availability of NIST personnel. Training is to occur within 14 days of installation. LINE ITEM 0004: WARRANTY The Contractor must provide at least one (1) year warranty on a new instrument or at least 90 day manufacturer warranty for a factory certified refurbished instrument. DELIVERY Delivery, installation and training shall be completed not later than 8 weeks after award. Delivery terms shall be FOB Destination. FOB DESTINATION MEANS: The contractor shall pack and mark the shipment in conformance with carrier requirements, deliver the shipment in good order and condition to the point of delivery specified in the purchase order, be responsible for loss of and/or damage to the goods occurring before receipt and acceptance of the shipment by the consignee at the delivery point specified in the purchase order; and pay all charges to the specified point of delivery. EVALUATION CRITERIA AND BASIS FOR AWARD The Government intends to award a purchase order resulting from this solicitation to the responsible quoter whose quotation is the lowest priced, technically acceptable quotation. The trade-in credit will be included and considered when evaluating the overall price. Technically acceptable means that the Contractor provides the required instrument (line item 0001) and all requirements of Line Items 0002 and0003 shall be met. PRICE Price shall be evaluated for all quoters whose quotations are determined technically acceptable. Price will be evaluated to determine that total price is consistent with the technical portion of the quotation and is a fair and reasonable overall price to the Government. REQUIRED SUBMISSIONS All quoters shall submit the following: 1) An original and one copy of an FOB Destination price quotation which addresses all Line Items with the trade-in credit separately identified; 2) Two (2) originals of technical description and/or product literature. Quoters shall include the manufacturer, make and model of the product, manufacturer sales literature or other product literature which CLEARLY DOCUMENTS that the offered product is the required brand name product and meets the minimum specifications stated herein. It is the responsibility of the quoter to ensure that all requirements are clearly documented; 3) A description of the proposed warranty; 4) This is an Open-Market Combined Synopsis/Solicitation for equipment as defined herein. The Government intends to award a Purchase Order as a result of this Combined Synopsis/Solicitation that will include the terms and conditions that are set forth herein. In order to facilitate the award process, ALL quotes shall include a statement regarding the terms and conditions herein as follows: The offeror shall state "The terms and conditions in the solicitation are acceptable to be included in the award document without modification, deletion, or addition." OR The offeror shall state "The terms and conditions in the solicitation are acceptable to be included in the award document with the exception, deletion, or addition of the following: Offeror shall list exception(s) and rationale for the exception(s) 5) The DUNS number for the quoter's active System for Award Management (SAM) registration. Quoters must have an active registration at www.SAM.Gov when the quotation is submitted to be considered for award; All quotes must be sent to the National Institute of Standards and Technology, Acquisition Management Division, Attn: Erik Frycklund, 100 Bureau Drive, Stop 1640, Gaithersburg, MD 20899-1640. Offerors shall ensure the RFQ number is visible on the outermost packaging. Submission must be received by 12:00 p.m. local time on Thursday, September 18, 2014. E-MAIL QUOTES SHALL BE ACCEPTED AND ARE PREFERRED. FAX QUOTES SHALL NOT BE ACCEPTED. PROVISIONS AND CLAUSES The full text of a FAR provision or clause may be accessed electronically at www.acquisition.gov. The following provisions apply to this acquisition: 52.212-1, Instructions to Offerors - Commercial with the Addendum to 52.212-1; 52.212-3, Offeror Representations and Certifications - Commercial Items; In accordance with FAR 52.212-3 Offeror Representations and Certifications - Commercial Items, offerors must complete annual representations and certifications on-line at www.SAM.Gov. If paragraph (j) of the provision applies, a written submission is required; The following clauses apply to this acquisition: 52.212-4 Contract Terms and Conditions - Commercial Items; 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items including subparagraphs: 52.203-6, Restrictions on Subcontractor Sales to the Government 52.209-6,Protecting the Government's Interests when Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment 52.219-28, Post Award Small Business Program Representation 52.222-3, Convict Labor 52.222-19, Child Labor--Cooperation with Authorities and Remedies 52.222-21, Prohibition of Segregated Facilities 52.222-26, Equal Opportunity 52.222-36, Affirmative Action for Workers with Disabilities 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving 52.225-1, Buy American---Supplies 52.225-13, Restrictions on Certain Foreign Purchases 52.232-33, Payment by Electronic Funds Transfer-System for Award Management 52.247-34, FOB Destination; and Department of Commerce Agency-Level Protest Procedures Level above the Contracting Officer is also incorporated. It can be downloaded at www.nist.gov/admin/od/contract/agency.htm.
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