SPECIAL NOTICE
A -- TECHNOLOGY/BUSINESS OPPORTUNITY INFRARED (IR) PHOTON-SENSITIVE SPECTROMICROSCOPY IN A CRYOGENIC ENVIRONMENT
- Notice Date
- 4/22/2015
- Notice Type
- Special Notice
- NAICS
- 238990
— All Other Specialty Trade Contractors
- Contracting Office
- Department of Energy, Lawrence Livermore National Laboratory (DOE Contractor), Industrial Partnerships & Commercialization, 7000 East Avenue, L-795, Livermore, California, 94550
- ZIP Code
- 94550
- Solicitation Number
- FBO292-15
- Archive Date
- 5/25/2015
- Point of Contact
- Connie L Pitcock, Phone: 925-422-1072
- E-Mail Address
-
pitcock1@llnl.gov
(pitcock1@llnl.gov)
- Small Business Set-Aside
- N/A
- Description
- Opportunity : Lawrence Livermore National Laboratory (LLNL), operated by the Lawrence Livermore National Security (LLNS), LLC under contract no. DE-AC52-07NA27344 (Contract 44) with the U.S. Department of Energy (DOE), is offering the opportunity to establish partnerships to conduct further research and development of this technology and obtain licensing rights for commercialization. Background : Infrared spectroscopy is a powerful tool well-recognized as suitable for use in a variety of applications including cell biology, drug discovery, chemical composition analysis and material analysis. However, IR spectromicroscopy detection is limited by the signal-to-noise ratio achievable in a given IR spectromicroscopy system, while the main noise contribution in Mid-IR spectromicroscopy is thermal radiation background. It would be beneficial to provide new systems, methods, and/or computer program products enabling infrared spectromicroscopy such that, particularly in the mid-IR and far-spectral regions, single-photon sensitive Mid-IR spectromicroscopy techniques can be employed to minimize radiational load on the system and permit mid-IR and far-IR emission study of small and/or delicate samples such as living cells, small biomolecules, etc. Potentially, a single molecular detection can be achieved. Description : A key element of this invention is the recognition that all life-important chemical interaction is situated in the mid-to-far infrared energy range. LLNL's Infrared (IR) Photon-Sensitive Spectromicroscopy invention is a system designed to suppress thermal radiation background and to allow IR single photon-sensitive spectromicroscopy of small samples by using absorption, reflection, and emission/luminescence measurements. Advantages : It is essential for the use of this invention to have single photon detector operating in Mid-IR, and it is desirable to have it operating in Far-IR spectral region. LLNL's system permits the study of mid-IR emission of living cells, which characterize ongoing metabolic or other cell biochemical processes. It also makes it possible to use resonant light scattering, photoluminescence, or other single-photon techniques in mid-IR with living cells. Currently, none of these methods of study are available with single photon sensitivity. Potential Applications : LLNL envisions this invention to have broad range of applications where chemical sensitivity on single molecular level is beneficial, including cell chemical imaging, non-destructive and safe cell analysis, nondestructive embryo evaluation for extra corporal fertilization techniques or cloning, drug development, and cellular level biofeedback for drug evaluation/development or for direct therapeutic applications, cryo-electron microscopy, material science, trace organic impurities detection, express biological sample analysis and security applications. Development Status: LLNL has filed a patent application covering this invention. LLNL is seeking industry partners with a demonstrated ability to bring such inventions to the market. Moving critical technology beyond the Laboratory to the commercial world helps our licensees gain a competitive edge in the marketplace. All licensing activities are conducted under policies relating to the strict nondisclosure of company proprietary information. Please visit the IPO website at https://ipo.llnl.gov/resources/industry/working-with-us for more information on working with LLNL and the industrial partnering and technology transfer process. Note: THIS IS NOT A PROCUREMENT. Companies interested in partnering with LLNL to conduct further research and development and commercializing LLNL's INFRARED (IR) PHOTON-SENSITIVE SPECTROMICROSCOPY IN A CRYOGENIC ENVIRONMENT technology should provide a written statement of interest, which includes the following: 1. Company Name and address. 2. The name, address, and telephone number of a point of contact. •3. A description of corporate expertise and facilities relevant to commercializing this technology. Written responses should be directed to: Lawrence Livermore National Laboratory Industrial Partnerships Office P.O. Box 808, L-795 Livermore, CA 94551-0808 Attention: FBO 292-15 Please provide your written statement within thirty (30) days from the date this announcement is published to ensure consideration of your interest in LLNL's INFRARED (IR) PHOTON-SENSITIVE SPECTROMICROSCOPY IN A CRYOGENIC ENVIRONMENT technology.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/DOE/LLNL/LL/FBO292-15/listing.html)
- Record
- SN03707084-W 20150424/150422234511-4fef3f1218406ff2d0293d9789be5909 (fbodaily.com)
- Source
-
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