SOURCES SOUGHT
66 -- Light Sheet Microscope for NIDA IRP
- Notice Date
- 4/30/2015
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SS-15-327
- Archive Date
- 5/26/2015
- Point of Contact
- Lauren M. Phelps, Phone: 3015942490
- E-Mail Address
-
lauren.phelps@nih.gov
(lauren.phelps@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, MD 20892, UNITED STATES. Introduction: THIS NOTICE IS POSTED CONCURRENTLY WITH NOTICE HHS-NIH-NIDA-SSSA-SBSS-15-326 WHICH IS SPECIFIC TO SMALL BUSINESSES. HHS-NIH-NIDA-SSSA-SS-15-327, HOWEVER, IS OPEN TO RESPONSE FROM BUSINESSES OF ALL SIZE CLASSIFICATIONS. This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified business sources, (2) whether they are large businesses; small businesses; HUBZone small businesses, service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. Purpose and Objectives for the Procurement: The purpose of this potential procurement is to provide the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) Histology Core with one (1) light-sheet microscope (LSM) to perform image analysis of histological samples. Project Requirements: The contractor shall provide one (1) light sheet microscope (LSM) with the following features and associated equipment and software: 1. The LSM must come with all software and hardware necessary to fully utilize the LSMs capabilities. 2. The LSM must offer a single, integrated LSM capable of imaging whole mice brains and partial samples of rat, monkey and human brain tissue up to 10 mm wide x 10 mm length x 10 mm height. 3. The LSM stage must move in 3 dimensions at least 10 mm on each x, y and z axis. 4. The LSM must include an integrated automatized stage that allows imaging at different places of the tissue sample by moving the stage with the assistance of computer-aided software. 5. The LSM must be capable of magnification from 0.63x to 20x. 6. The LSM must be capable of changing magnification without changing or draining the imaging chamber. 7. The LSM must include motorized adjustable fine and course adjustment of focus. 8. The LSM must produce an even focus throughout the images sampled and keep the same z focal plane in adjacent fields as it move the stage to the next field of view in either x or y. 9. The LSM must produce an even focus throughout the images sampled at any magnification. 10. The LSM must be able to stitch multiple images together without producing gaps or cross-overlap of artifacts. 11. The LSM must be capable of producing 3D images stacks free of gaps or cross-overlap of artifacts. 12. The LSM must produce images with uniform lighting. The LSM must have a sheet of light free of stripes caused by an uneven light path 13. The LSM must have at least six (6) light-sheet paths to maximize evenness of excitation through large size samples. 14. The LSM must be able to selectively excite at the focal plane to reduce bleaching and photo toxicity. The sheet of light shall not be more that 3 µm in height. 15. The LSM must have lasers to excite samples at 405, 488, 561, 640, 785 nm wavelengths. 16. The LSM must capture images of samples stained with commercially available fluorescence dyes and fluorescence antibodies such as DAPI, FITC, TRITC, DyLight 405, Cy2, Cy3, Cy5, and Cy7. 17. The LSM must have a high resolution camera sensitive to images within visible and far red light spectrum. The LSM resolution must be sensitive from 370 to 1100 nm light wavelengths. 18. The LSM must have a high resolution camera capable of image light low signal at < 2 electron RMS at speeds of 30 frames/s. 19. The LSM must have a high resolution camera of at least 2560 x 2160 pixels and a pixel size no bigger than 6.5 x 6.5 µm. 20. The LSM stage must be able to hold sample process for tissue clearing methods such as CLARITY and 3DISCO. 21. The LSM must come with software and hardware to operate the LSM with full function. Accordingly, the LSM must come with a computer. 22. The LSM computer must run 64-bit Windows 7 and software must be capable of controlling the LSM 3D image acquisition. 23. The LSM must come with a two-year on-site warranty. After purchase and prior to delivery, test images from the purchased tool shall be provided by the vendor for demonstration of the resolution and 3D imaging. Test images shall be of cleared brain tissue and shall be reviewed and accepted by the NIDA. These test images must be acquired in a LSM prior to delivery of the purchased system. All LSM tools and features must be fully integrated and tested in the LSM factory prior to delivery to the NIDA. The test images must later be reproduced at the customer site. Following installation, the LSM company must provide on-site LSM applications training to familiarize users with the proper functioning and control of the LSM, particularly as it relates to beam control requirements for standard sample imaging of cleared tissue. This training shall include information on how to safely and efficiently mount specimens in the chamber of the stage, as well as training on how to perform imaging of the sample and 3D reconstruction through the software provided by the contractor. Training must be provided immediately following installation of the equipment. Anticipated Period of Performance: It is expected that all project requirements will be delivered within sixteen (16) weeks after receipt of order. Training must be provided immediately following installation of the equipment. A firm fixed price contract is contemplated. Capability Statement: Contractors that believe they possess the ability to provide the required equipment should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. Contractors must provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Lauren Phelps, Contract Specialist, at Lauren.Phelps@nih.gov in MS Word format by or before the closing date of this announcement. All responses must be received by the specified due date and time in order to be considered. Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price contract.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SS-15-327/listing.html)
- Place of Performance
- Address: Baltimore, Maryland, 21224, United States
- Zip Code: 21224
- Zip Code: 21224
- Record
- SN03715788-W 20150502/150430235346-bbae5108736e9bd53a1339a7e88c13ac (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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