SOLICITATION NOTICE
A -- Provide Big Dye Terminator (BDT) v1.1 RR-5000 & Sequence Buffer; POP-7 Polymer Bottles and 5X Sequence Buffer Bottles in support of Naval Medical Research Center (NMRC), Silver Spring MD
- Notice Date
- 6/19/2015
- Notice Type
- Presolicitation
- NAICS
- 325414
— Biological Product (except Diagnostic) Manufacturing
- Contracting Office
- Department of the Navy, Bureau of Medicine and Surgery, Naval Medical Logistics Command, 693 Neiman Street, FT Detrick, Maryland, 21702-9203, United States
- ZIP Code
- 21702-9203
- Solicitation Number
- N32398BigDyeTerminator
- Archive Date
- 7/21/2015
- Point of Contact
- Ronald Stephen Sanford, Phone: 3016199330
- E-Mail Address
-
ronald.s.sanford2.civ@mail.mil
(ronald.s.sanford2.civ@mail.mil)
- Small Business Set-Aside
- N/A
- Description
- The Naval Medical Logistics Command (NMLC) intends to award a sole source contract under the authority of FAR 6.302-1 to Life Technologies Corporation, 3175 Staley Road, Grand Island, NY 14072-2090 to provide Big Dye Terminator (BDT) v1.1 RR-5000 & Sequence Buffer; POP-7 Polymer Bottles and 5X Sequence Buffer Bottles in support of Naval Medical Research Center (NMRC), Silver Spring MD. The objective of this requirement is to improve bone marrow transplant outcomes. The estimated period of performance of the project is 12 months. BDT v.1.1 must be compatible with the Applied Biosystems 3730x1 analyzer. Life Technologies Corporation is currently the only producer, manufacturer and distributer of the BDT v.1.1. that is compatible with the Applied Biosystems 3730x1 analyzer. The BDT v1.1 is a chemistry system that results in one of four highly specific fluorescent molecules, one each representing adenine, guanine, cytosine, or thymine, the four bases used by most organisms including humans to code for all genes. These four colored fluorescent molecules are the four colored markers detected by the Deoxyribonucleic acid (DNA) sequencing equipment, the Applied Biosystems DNA sequencer used for the Human Leukocyte Antigen (HLA) genetic tests. The test system tests HLA molecular strings (exons) representing the part of the HLA gene that gives HLA its biologic function (called antigen recognition site) and associated unique sequence of DNA bases. Each string of bases is 200 - 350 bases in length and is considered a short reading sequence. These reagents have been optimized by the Bone Marrow Research Directorate for DNA sequencing applications that are performed on the Applied Biosystems DNA Analyzer as required for acceptable clinical and research results needed for marrow transplantation. The BigDye Terminator v1.1 does provide DNA base calls, unambiguous separation of each color fluorescent molecule at each base position, and provides results for HLA molecules obtained from dried bucal swab samples. The Bone Marrow Research Program currently utilizes two Applied Biosystems 3730xl DNA analyzers which require the BDT v1.1 sequencing kits in order to operate the instrument and there are no acceptable alternate reagents. These reagents are used to perform clinical and bone marrow research projects. Life Technologies Corporation has been able to demonstrate on the HLA genes sequence based typing (SBT), Killer-cell immunoglobulin-like receptor (KIR) genes SBT and detection of HLA and KIR novel genes using these reagents. HLA and KIR genes typing are very critical for the treatment of leukemia patients and improving bone marrow transplant outcomes. Without the BDT v1.1 sequencing kits, the HLA/KIR genes SBT experiment would not be possible. A sources sought notice was issued on 03 June 2015 for this requirement and the Government determined after the review of capability statements, that no other source had the capability to perform the required work. This notice of intent is not a request for competitive proposals and no solicitation document exists for the requirement. Sources interested in responding to this notice are required to submit a capability statement that includes management and technical data and cost information, in sufficient detail and with convincing evidence that clearly demonstrates the capability to perform the required work. Capability statements shall not exceed 1 (8.5 x 11 inch) page using a font size no smaller than 10-point. All capability statements received by the due date of this notice will be considered by the Government. A request for documentation or additional information will not be considered as an affirmative response. A determination by the Government not to compete based on responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement or to proceed with a sole source contract. Capability statements are due by 12:00 PM Eastern Time, 06 July 2015. Capability statements shall be submitted by e-mail ONLY as a Microsoft Word or Adobe PDF attachment to the following address: ronald.s.sanford2.civ@mail.mil.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/DON/BUMED/N62645/N32398BigDyeTerminator/listing.html)
- Place of Performance
- Address: Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, Maryland, 20910, United States
- Zip Code: 20910
- Zip Code: 20910
- Record
- SN03770079-W 20150621/150619234535-48d55c4e7432a136e50c25d61a48d125 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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