SPECIAL NOTICE
A -- Self-evolving and Adapting Therapeutics (ADAPT) RFI, DARPA-SN-15-54 - DARPA-SN-15-54
- Notice Date
- 7/23/2015
- Notice Type
- Special Notice
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Other Defense Agencies, Defense Advanced Research Projects Agency, Contracts Management Office, 675 North Randolph Street, Arlington, Virginia, 22203-2114, United States
- ZIP Code
- 22203-2114
- Solicitation Number
- DARPA-BAA-15-54
- Archive Date
- 9/9/2015
- Point of Contact
- Dr. Jim Gimlett,
- E-Mail Address
-
DARPA-SN-15-54@darpa.mil
(DARPA-SN-15-54@darpa.mil)
- Small Business Set-Aside
- N/A
- Description
- Self-evolving and Adapting Therapeutics (ADAPT) RFI, DARPA-SN-15-54 The Biological Technologies Office (BTO) of the Defense Advanced Research Projects Agency (DARPA) is requesting information on revolutionary ideas to radically change the existing paradigm for treating and controlling a variety of dynamic diseases and biological threats, such as rapidly mutating viruses, drug-resistant bacteria and evolving chronic pathologies and conditions. DARPA requests information on new research approaches and novel therapeutic paradigms targeting the mutating and evolving character of pathogens and/or the dynamic host response. Of particular interest are novel therapeutics engineered for "auto-adaptive" release, pathogen- or disease-triggered expression/activation, and/ or therapeutics that control disease spread by self-transmitting within an individual and through populations (e.g., through drug persistence, and person-to-person transmissibility). These adaptive therapies may address not only fast-evolving dynamic pathogens and diseases, but also individual variability of disease and host response by co-evolving control mechanisms, or adaptive targeted delivery and/or release based on individual dynamics (e.g., through optimal timing, continuous monitoring of host response while modulating immune components, or co-evolving control agents). See Attachment for more information and submission details.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-BAA-15-54/listing.html)
- Record
- SN03807598-W 20150725/150723235008-b8334134ee199c4bd4325852f49741b4 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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