SOLICITATION NOTICE
B -- Single Award IDIQ for RNA Sequencing Services - RFQ, NIHES2015052 RNA Sequencing Services Single Award IDIQ
- Notice Date
- 7/23/2015
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Office of Acquisitions, Office of Management, 530 Davis Drive, Durham, North Carolina, 27713, United States
- ZIP Code
- 27713
- Solicitation Number
- NIHES2015052
- Archive Date
- 8/14/2015
- Point of Contact
- Onyenauché Washington, Phone: (919) 541-0423
- E-Mail Address
-
uche.washington@nih.gov
(uche.washington@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Attachment 1 - SOW, NIHES2015052 RNA Sequencing IDIQ RFQ, NIHES2015052 RNA Sequencing Services Single Award IDIQ This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 in conjunction with FAR 13, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (1) This solicitation document, NIHES2015052, is issued as a Request for Quotation (RFQ) to provide continued support of NextGen sequencing service's for the Epigenomics Core Laboratory at the National Institute of Environmental Health Science (NIEHS) located in Research Triangle Park, North Carolina. (2) This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Regulation (FAR); HHS Acquisition Regulation (HHSAR); Federal Acquisition Circular (FAC) 2005-82 effective May 7, 2015. (3) Notice of Set-Aside, Associated NAICS Code, and Size Standard: This solicitation competed on a full and open competitive basis. The associated NAICS code is 541380; "Testing Laboratories" and has a size standard of $15M. (4) List of Contract Line Item Number(s) and items, quantities and units of measure, (including option(s): See document titled RFQ, NIHES2015052, RNA NextGen Sequencing. (5) Description of Requirements for the Items to be Acquired: The purpose of this acquisition is to provide continued support of NextGen sequencing service's in progress that support Intramural Research Division (IRD) research objective's and to further explore how human health and human disease are caused by the interactions of the environment. The Contractor is required to provide NextGen Sequencing services that include: high quality NextGen library construction with proper QC confirmation, NextGen DNA or RNA sequencing runs/lanes of high quality constructed libraries with accompanying bioinformatics support. The continuity of sequencing information will provide vital information to on-going investigations regarding environmental disease mechanisms and the genetic component involved in causes, outcomes and progression of environmental diseases. The Contractor is also required to perform the following tasks:  - NextGen Sequencing;  - RNA or DNA extraction;  - DNA library construction;  - Sequence analysis;  - NextGen Sequence Bioinformatics Data Analysis;  - Data output file; and  - Mapping sequence data file More specifically, the Contractor shall provide the following:  - Sequencing services to IRD using the same technology and novel form of analysis (Illumina MiSeq and NextSeq 500 technologies) as currently being used;  - Produce high dimensionality of sequencing data;  - Identify differences in sequencing data using methods that not yield significant false positives;  - Use a DNA sequencing analysis data method that can mitigate the multiple testing issues by calculating a false discovery rate from a reference data distribution generated from our experimental data;  - Provide sequencing support that will provide the data in both fastq and in cel file format. The.cel format data is required to allow IRD to compare the RNA-seq results to previously obtained microarray results;  - Provide reliable sequence data necessary with low error within the sequencing data;  - Provide NextGen data to produce enough sequencing reads to meet the needs of DIR researchers;  - Provide a combination of Illumina Bio-analyzer and the novel bio-informatic analysis;  - Ensure method used mitigates the multiple testing issues by calculating a false discovery rate from a reference data distribution generated from our experimental data; and  - Allow researchers to accurately determine error rate and provide the best data possible (6) Date(s) and place(s) of performance and acceptance and FOB point: The opportunities for sample degradation and compromising the quality of data are greater with the continued movement of samples to various sites for analysis, therefore; analysis shall take place in a single facility located within the contiguous United States (CONUS). The contract's anticipated ordering period shall be from 15 August 2015 through 14 August 2016. Specific performance dates and quantities will be specified on each individual task order. (7) The provision at FAR 52.212-1, Instructions to Offerors -- Commercial, applies to this acquisition. See document titled RFQ, NIHES2015052, RNA NextGen Sequencing. (8) Applicability of the provision at FAR 52.212-2, Evaluation -- Commercial Items. See document titled RFQ, NIHES2015052, RNA NextGen Sequencing. (9) FAR 52.212-3, applies to this acquisition: Representation, Certifications, and Other Statements of Offerors - In accordance with provisions FAR 52.212-3, Offeror Representations and Certifications--Commercial Items, IF YOU INTEND TO SUBMIT A PROPOSAL, YOU MUST: (1) Go to the Online Representations and Certifications Application (ORCA) and complete the Representations and Certifications. Offerors must access ORCA through the System for Award Management (SAM) at http:// www.sam.gov; and (2). Complete, and INCLUDE as part of your price proposal. (10) FAR 52.212-4 Contract Terms and Conditions Commercial Items, applies to this acquisition. See document titled RFQ, NIHES2015052, RNA NextGen Sequencing. (11) FAR 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders--Commercial Items. See document titled RFQ, NIHES2015052, RNA NextGen Sequencing. (12) The Date, Time and Place Offers are Due: The Quoter shall submit dated quote to the following e-mail address: uche.washington@nih.gov at or before Thursday, 30 July 2015 at 12:00 PM EST. (13) The point of contact (POC) for this acquisition is Ms. Onyenauche Washington at (919) 541-0423/uche.washington@nih.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIEHS/NIHES2015052/listing.html)
- Record
- SN03807642-W 20150725/150723235035-cd5639173de39906fdcc8baee305f995 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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