SOLICITATION NOTICE
66 -- SpectraMax i3 with ScanLater WesternBlot Cartridge
- Notice Date
- 8/6/2015
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Library of Medicine, 6707 Democracy Blvd., Suite 105, Bethesda, Maryland, 20894, United States
- ZIP Code
- 20894
- Solicitation Number
- NIHLM2015-010907
- Archive Date
- 9/5/2015
- Point of Contact
- Linda E Smith, Phone: 3018277788
- E-Mail Address
-
linda.smith2@nih.gov
(linda.smith2@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National institutes of Health, National Institutes of Health (NIH), National Institute of Diabetes and Digestive Kidney Diseases (NIDDK), 6707 Democracy Boulevard, II Democracy Plaza, Suite 700W, Bethesda, Maryland 20892. Description National Institute of Diabetes and Digestive Kidney Diseases (NIDDK intends to procure on a sole source basis with Molecular Devices of 1311 Orleans Drive, Sunnyvale, California 94089. The National Institutes of Health (NIH), National Library of Medicine (NLM), Synthetic Bioactive Molecules Section of the Laboratory of Bioorganic Chemistry is involved in the discovery and development new molecules with medicinal value or for applications to diagnostics. Some of these molecules have the potential to become therapeutics or to be used as important components in diagnostic applications that signal the presence of disease. Applications in either area are of great benefit to human heath and thus to NIDDK's mission. Research conducted in the Laboratory of Bioorganic Chemistry involves synthesis of biologically active molecules called peptide nucleic acids (PNAs). This purchase requisition is urgently needed to obtain instrumentation required to characterize and study PNAs ability to detect nucleic acids from pathogens. Each PNA must be able to recognize and bind its DNA or RNA target nucleic acid sequence, and without this instrumentation we cannot continue our research on the properties of PNA and their development as components of diagnostic kits for pathogens. The same instrumentation will also facilitate our research on a small molecule and its ability to inhibit HIV. Using a small molecular scaffold, we have designed a molecule that inactivates the nucleocapsid protein 7 of HIV. Without this protein, HIV cannot properly mature. We are studying the mechanism of how this molecule inactivates nucleocapsid protein 7 in HIV, and we urgently need this instrumentation to continue our investigation into the mechanism of action for the molecule. We hope that with a better mechanistic understanding of the chemical biology of the molecule that it will help further the development into a drug to treat HIV infection. The instrumentation in our lab is specific to our needs for the study of PNA binding to nucleic acids and inactivation of nucleocapsid protein 7 by our small molecules, and it must be able to monitor fluorescence in several plate formats. In addition, the instrumentation must have software that runs from a PC which can automatically process the data and export it in formats compatible with other computers. Therefore the instrumentation must meet the following specs: Use monochrometers for tunable absorbance, fluorescence, and luminescence, and perform readings from top and bottom of plates. Operate without the need for additional filters Use LEDs and xenon flash for fluorescent light source, and automatically switch as needed between sources Have an upgradable feature for time-resolved fluorescence. Perform automatic Z-height selection that adjusts for microplates. Have automatic wavelength selection that determines how to minimize background Has automatic plate definitions for new plates Performs pathlength corrections Comes with specific software and PC to run instrumentation and perform data analysis. Performs Western Blot analysis for analysis of Click products from cell extracts labeled with biotin-azide. This acquisition will be processed in accordance with simplified acquisition procedures as stated in FAR Part 13.106-1(b)(1). The North American Industry Classification System Code is 334516 and the business size standard is 500. Only one award will be made as a result of this solicitation. This will be awarded as a firm-fixed price type contract. The period of performance shall be twelve (12) months from date of award. This is not a solicitation for competitive quotations. However, if any interested party believed they can meet the above requirement, they may submit a statement of capabilities. All information furnished must be in writing and must contain sufficient detail to allow the NIDDK to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NIDDK Acquisitions Branch on or before 11:00 AM EST on Tuesday, August 21, 2015. Electronic submissions will be accepted or they can be mailed to the DK Acquisitions Branch to the address stated above. All questions must be in writing and can be faxed to 301-480-4226 or emailed to Linda Smith, Contract Specialist, Linda.Smith2@nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractor must be registered and have valid certification in the System for Award Management (SAM) [formerly CCR] http://www.sam.gov. No collect calls will be accepted. Please reference solicitation number NIHLM2015-010907 on all correspondences. Confidentiality - No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/OAM/NIHLM2015-010907/listing.html)
- Place of Performance
- Address: Bethesda Main Campus, Bethesda, Maryland, 20817, United States
- Zip Code: 20817
- Zip Code: 20817
- Record
- SN03826863-W 20150808/150806235320-45a9c8b2645da74be28e46bd5655b89d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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