SOLICITATION NOTICE
R -- Ultramicro Scale Analytical Immunochemistry Research Support
- Notice Date
- 9/4/2015
- Notice Type
- Presolicitation
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-EB-2015-249-CDB
- Archive Date
- 9/26/2015
- Point of Contact
- Chris Bocus, Phone: 3014027888
- E-Mail Address
-
chris.bocus@nih.gov
(chris.bocus@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA), intends to negotiate and award a purchase order on a sole source noncompetitive basis to Terence M Phillips, 4101 Albemarle St NW Apt 508, Washington, DC, 20016-2135, to provide Ultramicro Scale Analytical Immunochemistry Research Support to the National Institute of Biomedical Imaging and Bioengineering (NIBIB). BACKGROUND: The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. This is achieved through: research and development of new biomedical imaging and bioengineering techniques and devices to fundamentally improve the detection, treatment, and prevention of disease; enhancing existing imaging and bioengineering modalities; supporting related research in the physical and mathematical sciences; encouraging research and development in multidisciplinary areas; supporting studies to assess the effectiveness and outcomes of new biologics, materials, processes, devices, and procedures; developing technologies for early disease detection and assessment of health status; and developing advanced imaging and engineering techniques for conducting biomedical research at multiple scales. The Trans-NIH Biomedical Engineering and Physical Science (BEPS) Shared Resource, NIBIB collaborates with and supports scientists throughout the NIH Intramural Research Program. BEPS has a need for expertise in the development and application of ultramicro-scale analytical immunochemistry and its application to the analysis of analytes of clinical interest in biological samples derived from either animal or human origin. These samples, supplied by investigators throughout the NIH, include serum, plasma, urine, cerebrospinal fluid (CSF), saliva, and lymph. Additionally, analysis is required of selected tissues and cell culture fluids. This expertise will augment BEPS's capabilities in state-of-the-art ultramicro-scale analytical immunochemistry. The benefits are that such methods are highly sensitive and specific, and require extremely small sample volumes. Development and application of methods in ultramicro-scale analytical immunochemistry is an ongoing need in BEPS. PROCUREMENT: The statement of work includes the following: a. Use known/existing analytical methods to perform specific, quantitative immunochemical analyses of biological samples of less than 1 microliter volume and/or 0.5 microgram of weight. b. Design new analytical approaches to measure novel analytes, as required by the NIH investigators, of biological samples of less than 1 microliter volume and/or 0.5 microgram of weight. c. To develop new ultramicro analytical techniques and design experiments to elucidate the role of various immune system components in the pathogenesis of disease, through: • Characterization of reagent antibodies and evaluation of their specificities. • Immunoaffinity chromatography, using microscale apparatus including chip-based capillary electrophoresis with laser induced fluorescence detection. • Magnetic bead immunoaffinity isolation of microsamples prior to additional chemical and immunochemical analysis. • Microdissection of tissue sections to obtain samples from defined histological areas. • Microdialysis to collect samples from single cell cultures prior to chip-based immunoaffinity capillary electrophoresis (ICE) analysis. • Mass spectrometric analysis of isolated analytes to characterize their properties. d. To analyze data collected in the experiments above, and to produce detailed written reports of findings. ANTICIPATED PERIOD OF PERFORMANCE: Base Year: September 15, 2015 through September 14, 2016 Option 1: September 15, 2016 through September 14, 2017 Option 2: September 15, 2017 through September 14, 2018 JUSTIFICATION: The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted as prescribed in FAR Part 10-Market Research. Only one source is reasonable available to perform the requested services to meet the Government's requirements. Terence M Phillips has successfully developed novel and micro analytical techniques based on immunoaffinity recognition. His unique methods of chip-based immunoaffinity electrophoresis are required to complete the research goals of the project. The unique knowledge, ability and experience are essential for the analysis of micro samples of biological materials at the NIH. REGULATORY AUTHORITY: This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106-1(b) Soliciting from a single source, only one responsible source and no other supplies or services will satisfy agency requirements. ADDITIONAL INFORMATION: Industry Classification (NAICS) Code is 541690, Other Scientific and Technical Consulting Services and the Small Business Size Standard is $15,000,000. This acquisition is conducted in accordance with the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures. The solicitation document, the incorporated provisions and clauses are those in the Federal Acquisition Circular 2005-83, effective September 3, 2015. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by September 11, 2015 at 12:00 p.m. EST. Responses must reference synopsis number HHS-NIH-NHLBI-CSB-EB-2015-249-CDB, may be submitted to the National, Heart, Lung and Blood Institute, Office of Acquisition, COAC Services Branch, 6701 Rockledge Drive, Rm 6207, Bethesda, Maryland 20892-7902, Attention: Chris Bocus. Response may be submitted electronically to chris.bocus@ nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-EB-2015-249-CDB/listing.html)
- Place of Performance
- Address: Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN03873762-W 20150906/150905000109-67e40e011f938889538389030c4fe34b (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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