SOLICITATION NOTICE
66 -- Flow Cytometer
- Notice Date
- 9/11/2015
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Commerce, National Institute of Standards and Technology (NIST), Acquisition Management Division, 100 Bureau Drive, Building 301, Room B130, Gaithersburg, Maryland, 20899-1410, United States
- ZIP Code
- 20899-1410
- Solicitation Number
- NB647030-15-02738
- Archive Date
- 10/2/2015
- Point of Contact
- Angela L. Hitt, Phone: 3034977305
- E-Mail Address
-
angela.hitt@nist.gov
(angela.hitt@nist.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This solicitation, NB647030-15-02738, is issued as a request for quotation (RFQ). This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-84. The associated North American Industrial Classification System (NAICS) code for this procurement is 334516, with a small business size standard of 500 employees. This is unrestricted and all interested parties may submit a quotation. It is being issued using the simplified acquisition procedures under the authority of FAR 13.5 Certain Commercial Items. This combined synopsis/solicitation is for the following commercial item(s): CLIN 0001: One (1) Flow Cytometer to include installation, 1 year warranty, operations & maintenance manual for the analytical instrument, and training, Description of requirements for the items to be acquired for National Institute of Standards and Technology's (NIST) Material Measurement Laboratory: The Applied Chemicals and Materials Division is developing new metrologies for microbiological specimens of critical importance and relevant to national needs. Ongoing work on microbiologically influenced corrosion, microbial adhesion, and phase noise characterization of antimicrobial susceptibility can all benefit from the addition of a more quantitative cell characterization technique like flow cytometry. In addition, flow cytometry will provide a tool to launch new characterizations of complex and important microbiological samples, such as those from corrosion rich environments or medical implanted device infections, and their responses to interventions. The acquisition of a flow cytometer will add key cell analysis capabilities to the microbiology research ongoing for multiple projects within the division. Flow cytometers count bacteria as an endpoint assay, and can characterize live and dead portions of the population using the current live/dead staining system in use with the fluorescence microscope. This would mean that NIST could have much better quantitative characterization of the cell populations that go into experiments for both phase noise measurements for antibiotics testing, and QCM-D measurements for adhesion characterization. NIST is currently limited to characterization of cell counts by optical density and manual counts on the microscope, which are less informative, and lower throughput. A number of other assays are possible on the flow cytometer, including but not limited to, automation of the currently manual microscopic process of counting neural progenitor cells for other projects within ACMD. The Contractor shall provide one (1) analytical instrument system that meets the following minimum technical requirements. The Contractor shall install the instrument and provide training as described below. System Requirements: • Must be a benchtop flow cytometry instrument. • Must be a newly manufactured instrument (no refurbished or demo models). • May handle samples with either fluidic sheath flow or capillary flow; however there must not be a requirement for proprietary sheath fluid that can only be obtained from the manufacturer. • Must be able to run at user-adjustable flow rates. • Must be able to backwash and rinse flow cell, and decontaminate all areas of the instrument coming into contact with sample. • Must be able to run from a minimum sample volume of less than 500 microliters. • Must be able to detect a minimum particle size of 0.5 micrometers or less. • Must contain a 488 nm laser for excitation of fluorophores. The power of the 488 nm laser must be at least 50 mW. • Must contain a second laser between the wavelengths of 635 and 645 nanometers, with a minimum power of 50 mW. • Robustness in the optical alignment train is preferred. NIST will give additional consideration to those proposals that demonstrate a design that is inherently robust against misalignment or damage to the optical alignment. • Must contain forward scatter and side scatter detectors capable of detecting scatter from one or more of the instrument laser sources. • Must contain a set of four fluorescence detectors, capable of operating simultaneously, with the following characteristics: o One fluorescence detector with a detection peak between 510 and 540 nm, and a bandwidth less than or equal to 40 nm, which is able to detect emissions from SYTO9 dye. o One fluorescence detector with a detection peak between 570 and 590 nm, and a bandwidth less than or equal to 50 nm. o One fluorescence detector with a detection peak above 620 nm. Longpass filters are acceptable for this detector. It must be able to detect emissions from propidium iodide dye. o One fluorescence detector with a detection peak sufficient to detect emissions of dyes excited by the red laser. Longpass filters are acceptable for this detector. NIST will give additional consideration to those proposals that provide a fourth fluorescence detector meeting these specifications. • It is preferred that all wavelength filters for fluorescence detectors should be user-changeable. NIST will give additional consideration to those proposals that demonstrate a design that allows for user-changeable wavelength filters in a manner that is simple, quick and does not affect system operating characteristics. • Fluorescence detector voltages must be user-adjustable. • Must be bundled with acquisition and analysis software. • Must be bundled with a complete computer system including monitor, keyboard and mouse, capable of operating acquisition software for optimal system performance. The computing power shall meet the following specifications at a minimum: o Processor speed greater than 2 GHz o At least 4 GB RAM o Storage capacity greater than 250 GB • Must be able to export data files to.fcs format. • Must have a fluorescence sensitivity of <150 MESF for FITC dye. • Must have sufficient scatter resolution to resolve lymphocytes from monocytes and granulocytes. • Must be able to acquire over 500 events per second. • Must be compatible with running samples containing up to 20% ethanol. • The system must include an operations and maintenance manual covering proper operation, routine maintenance, and troubleshooting for the instrument and included software. o The manual shall be supplied in both hard copy and electronic formats. Installation: If laser alignment is required, the contractor shall install the instrument in Building 2, Room 2810, at NIST in Boulder, CO. Installation shall include, at a minimum, uncrating/unpacking of all equipment, set-up and hook-up of all equipment, start-up, demonstration of specifications, and removal of all trash. If laser alignment is not required, the installation can performed by the NIST Technical Point of Contact (TPOC) in consultation with the vendor, to demonstrate that the product meets all acceptance criteria stated by the manufacturer. Commercially available fluorescent beads may be used to demonstrate acceptance criteria. Contractors shall state clearly in their proposal whether laser alignment is or is not required, and whether installation by Contractor personnel is or is not required. Instrument will operate to manufacturer's specifications upon installation. Installation will take place during normal business hours, between 8:00 am and 5:00 pm Mountain Time, Monday through Thursday except Federal Holidays, and will be coordinated with the TPOC. Installation is to occur within 90 days of award. Warranty: A minimum one year warranty is required to be included in the purchase price. The warranty shall guarantee that the instrumentation will meet the manufacturer's specifications and be free from defects in material and workmanship for at least twelve months from the date of shipment. During the warranty period, repair or replacement of nonconforming goods will be provided by the manufacturer free of charge to the NIST Boulder campus. Repairs may be performed at NIST in Boulder, or at the manufacturer's preferred location if a loaner instrument is provided while the defective instrument is in transit outside of the laboratory. Training: Include training for up to 2 NIST personnel covering normal operation, troubleshooting, and routine maintenance. Training will be provided during normal business hours, between 8:00am and 5:00pm Mountain Time, Monday through Thursday, except Federal Holidays, and will be coordinated with the NIST Technical Point of Contact (TPOC) to ensure maximum availability of NIST personnel. Training is to occur within 14 days of installation. Training may be conducted through virtual communication channels (i.e., phone or videoconference). Period of Performance: The period of performance shall include delivery within 60 days, installation within 90 days, training within 104 days (14 days after installation), and a one year warranty period beginning from acceptance of the installed instrument. Place of Performance: All work shall be completed at the contractor's facility. Installation of the instrument and training shall be accomplished at NIST in Boulder, CO. Normal duty hours are Monday through Friday, 8:30 a.m. to 5:00 p.m. with the exception of Federal holidays. Government Furnished Property: The government will furnish a sturdy open bench to support the benchtop instrument. Deliverables: Description Quantity Due Date Analytical instrument (flow cytometer) One (1) 60 days after award of this requirement. Installation of the analytical instrument Once 90 days after award of this requirement. Operations and maintenance manual for the analytical instrument One (1) 90 days after award of this requirement Training of NIST personnel at NIST, Boulder, CO Once 14 days after installation. Performance Requirement Summary: The Contractor shall demonstrate that all performance standards in this statement of work have been met. General Information: Patent Rights: The Government retains a Government use license to all inventions arising from this work. BASIS OF AWARD: Award shall be made, if at all, to the responsible offeror whose offer conforms to the requirements of the solicitation, representing the best value to the Government considering the Government's evaluation of the following factors: Instrument capabilities, features, maintenance requirements, and price will be weighted equally in determining the best value. Delivery time will be taken into secondary consideration. NIST requires delivery within 60 days ARO, and installation within 90 days ARO. In evaluating quotations, all acceptable proposals must meet the minimum requirements. Exceedance of the minimum or optimal technical requirements will be evaluated and given additional consideration in the technical approach. In evaluating the relative merit and degree of exceedances, the requirement for user-changeable fluorescence detector bandwidth filters will be given priority, followed by robustness in the optical alignment train. Instructions to Offerors: • The Contractor must include pricing for consumable parts and required annual services. • The Contractor must include a recommended schedule for service and replacing consumables. • The Contractor must include their guaranteed delivery schedule. • The Contractor must supply pricing for an annual service agreement and/or consumables price list to maintain the equipment for the base year (outside of warranty expenses) and up to four option years. • The Contractor must supply calculations or data to support the performance requirements specified in the Statement of Work. Technical Capability: To be considered for award, all Contractors must meet the minimum performance specifications defined in the Statement of Work. In addition, Contractors that exceed the minimum performance specifications in specific measures will be awarded additional consideration. The factors that merit additional consideration, in order of importance from most important to least important, are the following: • user-changeable fluorescence detector bandwidth filters • robustness in the optical alignment train • configuration of laser and detector wavelengths for blue and red lasers and fluorescence detectors If the Contractor exceeds minimum requirements, then the Contractor will be held responsible for meeting the exceeded capabilities offered in their proposal. Price: In addition to the initial purchase price, factors involved in the total cost of ownership will also be evaluated in determining the price associated with the Contractor's proposal. The government will evaluate annual service requirements, consumable parts and their expected frequency of replacement. To summarize, the factors that will be evaluated in price are the following, in no particular order: Purchase price Annual service requirements Consumable parts The provision at FAR 52.212-1, Instructions to Offerors-Commercial, applies to this acquisition. Offerors shall meet the technical approach and relevant past performance. (See attached Instructions To Offerors). FAR 52.212-2, Evaluation -- Commercial Items, applies to this acquisition. (Quotes shall be evaluated in accordance with the criteria shown above). The quoter must have completed the provision at FAR 52.212-3, Offeror Representations and Certifications -- Commercial Items. Reps and certs must be uploaded to the System for Award Management at www.sam.gov. FAR 52.212-4, Contract Terms and Conditions -- Commercial Items, applies to this acquisition. FAR 52.212-5, Contract Terms and Conditions Required To Implement Statutes Or Executive Orders -- Commercial Items applies to this acquisition. Additional FAR 52.212-5 clauses cited in the clause applicable to this acquisition are: 52.204-10, Reporting Executive compensation and First-Tier Subcontract Awards 52.209-6, Protecting the Government' Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment 52.219-28, Post Award Small Business Program Re-representation 52.222-3, Convict Labor 52.222-19, Child Labor - Cooperation With Authorities And Remedies 52.222-21, Prohibition of Segregated Facilities 52.222-26, Equal Opportunity 52.222-36, Affirmative Action for Workers with Disabilities 52.222-50, Combating Trafficking in Persons 52.223-18, Contractor Policy to Ban Text Messaging While Driving 52.225-1, Buy American-Supplies 52.225-13, Restrictions on Certain Foreign Purchases 52.232-33, Payment by Electronic Funds Transfer 52.222-51, Exemption from Application of the Service Contract Labor Standards to Contract for Maintenance, Calibration, or Repair of Certain Equipment--Requirements FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998) This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at this/these address(es): at http://acquisition.gov/comp/far/index.html and http://www.osec.doc.gov/oam/acquistion_management/policy/default.htm FAR 52.225-18 - Place of Manufacture FAR 52.232-13, Notice of Progress Payments FAR 52.232-16, Progress Payments CAR 1352.213-70, Evaluation Utilizing Simplified Acquisition Procedures CAR 1352.215-70, Proposal Preparation CAR 1352.233-70, Agency Protests CAR 1352.233-71, GAO and Court of Federal Claims Protests FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998) This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this/these address(es): http://acquisition.gov/comp/far/index.html and http://www.osec.doc.gov/oam/acquistion_management/policy/default.htm FAR 52.232-40, Providing Accelerated Payments to Small Business Subcontractors. FAR 52.247-34, FOB Destination CAR 1352.201-70, Contracting Officer's Authority CAR 1352.209-72, Restrictions Against Disclosure CAR 1352.209-73, Compliance with the Laws CAR 1352.209-74, Organizational Conflict of Interest CAR 1352.237-71, Security Processing Requirements-No Risk CAR 1352.246-70, Place of Acceptance (a) The Contracting Officer or the duly authorized representative will accept supplies and services to be provided under this contract. (b) The place of acceptance will be: NIST 325 Broadway Shipping and Receiving Boulder, CO 80305 NIST LOCAL-04 BILLING INSTRUCTIONS (a) NIST prefers electronic Invoice/Voucher submissions and they should be emailed to INVOICE@NIST.GOV. (b) Each Invoice or Voucher submitted shall include the following: (1) Contract Number. (2) Contractor Name and Address. (3) Date of Invoice. (4) Invoice Number. (5) Amount of Invoice and Cumulative Amount Invoiced to-date. (6) Contract Line Item Number (CLIN). (7) Description, Quantity, Unit of Measure, Unit Price, and Extended Price of Supplies/Services Delivered. (8) Prompt Payment Discount Terms, if Offered. (9) Any other information or documentation required by the contract. (c) In the event electronic submissions are not used, The Contractor shall submit an original invoice or voucher in accordance with the payment provisions of this contract to: NIST: Accounts Payable Office 100 Bureau Drive, Mail Stop 1621 Gaithersburg, MD 20899-1621 NIST LOCAL-10 DELIVERY INSTRUCTIONS Contractor shall coordinate delivery including installation and training with the Technical Information Contact identified herein. The Contractor shall submit a Quote, to be received no later than 5 p.m. Mountain Time, Thursday, September 17, 2015, and must include the following: Company name, address, phone numbers, DUNS number, itemized quote including all minimum specifications. Quotes shall be delivered via email to angela.hitt@nist.gov. Please direct any questions regarding this solicitation to Angela Hitt at angela.hitt@nist.gov no later than 11:00 a.m. Mountain Time, Tuesday, September 15, 2015.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/DOC/NIST/AcAsD/NB647030-15-02738/listing.html)
- Place of Performance
- Address: U.S. Department of Commerce, National Institute of Standards and Technology (NIST), Acquisitions Management Division, 325 Broadway, Boulder, Colorado, 80305, United States
- Zip Code: 80305
- Zip Code: 80305
- Record
- SN03881469-W 20150913/150911234849-524d675a01dc0aec1908ebfdd5793899 (fbodaily.com)
- Source
-
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