SOLICITATION NOTICE
B -- Laboratory Testing Services - Cortisol and Salivary Melatonin Samples
- Notice Date
- 1/27/2016
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 621511
— Medical Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-CSS-16-141
- Archive Date
- 2/22/2016
- Point of Contact
- Keshia McDonald,
- E-Mail Address
-
keshia.mcdonald@nih.gov
(keshia.mcdonald@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA-SSSA-CSS-16-141 and the solicitation is issued as a Request for Quotation (RFQ). NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The NAICS code applicable to this requirement is 621511 – Medical Laboratories and the associated business size standard of $30 M. SET-ASIDE STATUS This acquisition is unrestricted and available for full and open competition. ACQUISITION AUTHORITY This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; FAR Subpart 13.5—Test Program for Certain Commercial Items; and FAR Part 12—Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-84, dated September 03, 2015. The resultant contract will include all applicable provisions and clauses in effect through this date. BACKGROUND INFORMATION The National Institute of Mental Health (NIMH), Intramural Research Program, Genetic Epidemiology Research Branch requires laboratory testing services on salivary cortisol and salivary melatonin samples with the goal of identifying biomarkers of mood disorder diagnostic subtypes and components and their familial heritability. The Contractor will be preforming assays on cortisol and melatonin samples and provide NIMH with a final report of analyzed data. The NIMH Family Study of Affective Spectrum Disorders is the largest contemporary controlled family study of the mood disorder spectrum that is based on a non-clinical sample of probands with mood disorders. The study includes assessment of comprehensive domains that may constitute biological markers of mood disorders including objective measures of daily rhythms of mood, sleep, activity and stressors using mobile technologies, psychophysiology, cognitive function, neuroimaging, sensory thresholds, temperamental measures, and autonomic reactivity. Most relevant to this proposed work is the in vivo sampling of salivary cortisol in conjunction with electronic diaries and activity monitors 4 times per day over two weeks in a subsample. This permits evaluation of circadian patterns of cortisol as well as its association with emotional states, dietary intake, pain, physical activity, sleep, and stressful events. PURPOSE OF THE REQUIREMENTS The Genetic Epidemiology Research Branch conducts population, clinical, and basic research on the developmental, genetic, and biological components of mood and anxiety disorders and comorbid medical disorders. Specifically, the goals of the section are to identify and study familial aspects of mood and anxiety disorders and comorbid conditions, and discern more clearly their early manifestations. This project examines salivary cortisol and melatonin levels. The major aim is to identify biomarkers of mood disorder diagnostic subtypes and components and their familial heritability. Specifically, the purpose of this requirement is as follows: (1) to examine circadian rhythms of cortisol and their relationship to emotional states and disorders, circadian rhythms, and activity levels; (2) to examine variability in nighttime melatonin by mood disorder; (3) to evaluate the associations between inflammatory, immunologic, cardiovascular and metabolic biomarkers with mood disorder subtypes and core features and their specificity; (4) to estimate the familial heritability of these biomarkers; and (5) to investigate the inter-relationships across these domains to determine whether they may emanate from common underlying biologic processes. PROJECT REQUIREMENTS The contractor must have the ability to complete the cortisol assays on the sample within 30 business days of receipt of the samples. In addition, the contractor must have the ability to complete the melatonin assays within 60 business days of receipt of the samples. GOVERNMENT RESPONSIBILITIES The Government will provide 3,000 salivary samples. During the 12 month period of performance, the Government may provide up to 3,000 additional salivary samples for testing purposes. Saliva will be used to quantify cortisol and melatonin. Saliva was obtained 4 times a day for 14 days for youth under age 30. Electronic diaries were used to determine the timing of sample collection. Measures of emotional states, pain, stressful life events, dietary intake and sleep were collected concomitant to the saliva samples at each measure. Intra familial correlations of daily cortisol patterns and nighttime melatonin levels will be evaluated. This study is unique in that it includes electronic diaries. These diaries permit the comparison of cortisol levels with mood, current context (location and current activity), last meal, and sleep data in addition to many other features. DELIVERABLES 1. A final report of all analyzed data. 2. The contractor is required to send the results of the assays in a timely fashion. The report shall cover all work completed during the contract period. This report shall also identify any problems that arose and a statement explaining how the problem was resolved. This report shall also identify any problems that have arisen but have not been completely resolved and provide an explanation. Timely submission of deliverables is essential to successful completion of the testing services requirement. All deliverables shall be prepared and submitted according to format, content, and schedule described in the SOW. All “hard copy” deliverables will be submitted on recycled content paper, and printed double sided. TRAVEL The government will not reimburse any costs incurred by the contractor for travel or personal expenses. DATA RIGHTS The National Institute of Mental Health shall have unlimited rights to and ownership of all data including reports. In addition, it includes any additional deliverables required by contract change. The definition of “unlimited rights” is contained in Federal Acquisition Regulation (FAR) 27.401, “Definitions.” FAR clause 52.227-14, “Rights in Data-General,” is hereby incorporated by reference and made a part of this contract/order. SECTION 508 – ELECTRONIC AND INFORMATION TECHNOLOGY STANDARDS The contractor shall comply with Section 508 of the Rehabilitation Act (29 U.S.C. § 794d), as amended by the Workforce Investment Act of 1998 (P.L. 105-220), August 7, 1998. CONTRACTOR EXPERIENCE REQUIREMENTS – KEY PERSONNEL The contractor must have first-hand experience in biologic assays. CONTRACT TYPE The Government intends to award a firm fixed price contract for this requirement. PERIOD OF PERFORMANCE The period of performance for this requirement is 12 months from date of award with one additional option year as the tables indicate below: Base Year (12 months from date of award) Type of Sample Quantity Price Total Cortisol 2500 $X per sample $X Melatonin 500 $X per sample $X Totals 3000 $X Option For Increased Quantity (12 months from date of award) Type of Sample Quantity Price Total Cortisol Up to 2500 $X per sample $X Melatonin Up to 500 $X per sample $X Totals 3000 $X Please note that this option will be authorized using the authority of FAR 52.217-6 Option for Increased Quantity. APPLICABLE CLAUSES AND PROVISIONS The following FAR clauses and provisions are applicable to this acquisition: 52.212-1 Instructions to Offerors-Commercial Items (APR 2014) 52.212-2 Evaluation-Commercial Items (Oct 2014) 52.212-3 Offeror Representations and Certifications-Commercial Items (Mar 2015) 52.212-4 Contract Terms and Conditions-Commercial Items (MAY 2015) 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (May 2015) 52.217-5 Evaluation of Options (JUL 1990) 52.217-7 Option for Increased Quantity (MAR 1989) 52.227-14 Rights in Data – General HHSAR 352.242-70 Key Personnel (JAN 2006) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. FAR 52.217-5 Evaluation of Options It is anticipated that any awards resulting from this CSS will contain option provision(s) and period(s). In accordance with FAR Clause 52.217-5, Evaluation of Options, (July 1990), the Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement, except when it is determined in accordance with FAR 17.206(b) not to be in the Government's best interests. Evaluation of options will not obligate the Government to exercise the option(s). FAR 52.217-6 Option for Increased Quantity The Government may increase the quantity of supplies called for in the Schedule at the unit price specified. The Contracting Officer may exercise the option by written notice to the Contractor within one day. Delivery of the added items shall continue at the same rate as the like items called for under the contract, unless the parties otherwise agree. Key Personnel - HHSAR 352.242-70 (January 2006) The key personnel specified in this contract are considered to be essential to work performance. At least 30 days prior to diverting any of the specified individuals to other programs or contracts (or as soon as possible, if an individual must be replaced, for example, as a result of leaving the employ of the Contractor), the Contractor shall notify the Contracting Officer and shall submit comprehensive justification for the diversion or replacement request (including proposed substitutions for key personnel) to permit evaluation by the Government of the impact on performance under this contract. The Contractor shall not divert or otherwise replace any key personnel without the written consent of the Contracting Officer. The Government may modify the contract to add or delete key personnel at the request of the Contractor or Government. EVALUATION CRITERIA FAR 52.212-2 Evaluation Criteria FAR clause 52.212-2, Evaluation-Commercial Items applies to this acquisition and the specific evaluation criteria to be included in paragraph (1) of that provision are as follows: The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. Technical acceptability will be evaluated based upon the following: 1. Corporate/Laboratory Experience (50%) 2. Delivery (50%) 3. Price Factor 1: Corporate/Laboratory Experience (50%) The offeror shall identify their experience in working with salivary assays and the laboratory capabilities and shall demonstrate their understanding of the requirements and tasks detailed in the CSS. Factor 2: Delivery (50%) The offeror shall describe their capability to adhere to the period of performance requirements listed under “project requirements.” Factor 3: Price The contractor shall offer a reasonable price in USD per sample as listed in the tables above as well as option pricing. REQUESTS FOR CLARIFICATION Requests for clarification may be submitted electronically in MS Office format to the Contract Specialist, no later than 02/03/2016 by 5:00 PM EST. Requests for clarification shall be sent to keshia.mcdonald@nih.gov. Responses to the clarifications will be provided electronically via FedBizOpps no later than 02/04/2016. QUOTATION SUBMISSION The response to this request for quotation is due on 02/07/2016, no later than 5:00 PM Eastern Standard Time (EST). All responses must be submitted via email to keshia.mcdonald@nih.gov and reference solicitation number HHS-NIH-NIDA-SSSA-CSS-16-141 in the subject line. RESPONSE FORMAT Responses to this solicitation must include sufficient information to establish the interested parties’ bona- fide capabilities of providing the required products. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. Contractors must provide their Company Name, Dun & Bradstreet Number (DUNS), Taxpayer Identification Number (TIN), Business Size, Physical Address, and Point of Contact Information in their responses. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.” The purpose of the written technical proposal is to assess the Contractor’s solutions and capabilities in relation to the specific objectives and requirements as described in the combined synopsis/solicitation. Responding Contractors shall submit their proposals electronically in Microsoft Office format via email to Keshia McDonald ( keshia.mcdonald@nih.gov ) by or before the date specified in the combined synopsis/solicitation (01/28/2016 at 11:00 AM EST). Offerors shall submit no more than seven (7) single-sided pages inclusive of text tables and graphics. Text must be 12-point Times New Roman font. Margins must be set at one (1) inch on top, bottom, left, right of each page. Text included within tables and graphics must contain 12-Point Times New Roman font. Resumes for key personnel may not be longer than two (2) single sided pages and are not included in the seven (7) page requirement. The Contractor shall submit its proposal electronically in a “read only” MS Office format. Proposals must clearly address the objectives, requirements, and technical evaluation criteria described in the combined synopsis/solicitation. Pricing will be evaluated separately from technical capabilities. All responses must be received by the closing date of this announcement and must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-16-141. Responses shall be submitted electronically to Keshia McDonald, Contract Specialist, at keshia.mcdonald@nih.gov.
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