SOLICITATION NOTICE
J -- Agena Premier Plan - MassARRAY® Compact System
- Notice Date
- 4/25/2016
- Notice Type
- Presolicitation
- NAICS
- 811219
— Other Electronic and Precision Equipment Repair and Maintenance
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-(HG)-2016-115-DM
- Archive Date
- 5/17/2016
- Point of Contact
- Dorothy Maxwell, Phone: 301-435-0352
- E-Mail Address
-
maxwelld@mail.nih.gov
(maxwelld@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION: THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). THIS IS A NOTICE OF INTENT, NOT A REQUEST FOR A PROPOSAL. A SOLICITATION DOCUMENT WILL NOT BE ISSUED AND PROPOSALS WILL NOT BE REQUESTED. The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a noncompetitive sole source basis to Agena Bioscience, 4755 Eastgate Mall, San Diego, California 92121-1971 to procure the following: Procurement: 1. Customer Site Engineering Support Event, Product Code: 69000, Quantity: One; 2. Premier Plan - MassARRAY® Compact System, Product Code: 63006, Serial Number: BA060483, Quantity: One; 3. Premier Plan - MassARRAY® Compact System, Product Code: 63006, Serial Number: BA080120; 4. Premier Plan - MassARRAY® Compact System, Product Code: 63008, Serial Number: 13P0523RS-01, Quantity: One; and 5. Service Plan (Included) - Database Server, Product Code: 000-DBS, Quantity: One. Background: The National Institute of Health (NIH) is the nation's leading medical research agency and the primary Federal agency seeking fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The National Human Genome Research Institute (NHGRI), mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. A critical part of the NHGRI mission continues to be the study of the ethical, legal and social implications (ELSI) of genome research. The Medical Genomics and Metabolic Genetics Branch/Molecular Genetics Section Investigators use a broad range of tools to understand how health and disease are related to genetic, genomic and metabolic variation. Investigators study a broad spectrum of disorders, from common diseases associated with common variants to the rarest diseases associated with uncommon, sometimes unique variants. Scientific Investigators sometimes study disorders that are not inherited at all, which are due to somatic mosaicism-a difference in genetic composition among cells in an individual. Additionally also study how the genome influences normal metabolic processes. MGMGB investigators apply tools ranging from high-throughput biology to clinical and animal research. A unifying theme in their research is that the human is the most complex, fascin MGMGB investigators use the rich resources and technologies of the Human Genome Project to develop more sophisticated ways of understanding pathophysiology, diagnosis and treatment of disease.ating and important system in which one can study the effects of heritable variation. Purpose and Objectives: The purpose of this procurement is to procure Agena Bioscience MassARRAY System Premier Service Agreement. NHGRI for eighteen years have been engaged in a large collaborative study entitled FUSION (Finland - United States Investigation of NIDDM), in which more than 20,000 individuals with type 2 diabetes (T2D) (and suitable controls) from Finland are being studied, using careful phenotyping of diabetes and diabetes-associated quantitative traits, and genome-wide genetic linkage and association. Large numbers of additional samples are also now available from several collaborators around the world including the Broad Institute, Diabetes Genome Initiative and the Wellcome Trust Case Control Consortium. NHGRI/MGMGB have developed and applied new high throughput genotyping approaches in the laboratory using the Agena Bioscience platform, which have allowed the collection of a massive amount of data from these Finnish diabetics and their families. Following the genome wide association study (GWAS) approach, single nucleotide polymorphisms have been selected and genotyped using the Agena Bioscience platform at NHGRI, The Broad institute and The Wellcome Trust. NHGRI/MGMGB have now contributed to the identification of no less than 32 loci for T2D, and have identified additional loci harboring variants that have important effects on obesity, fasting glucose, LDL and HDL cholesterol, triglycerides, blood pressure, and adult height. Continuing these approach scientific investigators anticipate the need to continue this approach to identify additional loci for hundreds of more SNPs in T2D and quantitative trait associated loci. The use of the same platform at NHGRI, The Broad Institute and The Wellcome Trust decreases the complexity of analysis significantly and increases the probability of success. NHGRI/MGMGB require a service and maintenance agreement to support the continual operation of the Agena Bioscience MassARRAY System in order for scientific research investigators to achieve the above mentioned objectives. Additional Information: NHGRI MGMGB have upgraded the genotyping capabilities in the Collins lab to increase throughput and versatility as well as lower the cost of high throughput SNP analysis. In increasing the versatility we are able to optimize the type of genotyping reaction to facilitate smaller studies with a large number of samples as well as larger numbers of SNPs on few samples for association discovery studies. NHGRI/MGMGB continues to use MassARRAY System in order to test as many as 36 SNPs in each multiplex reaction. The Agena Bioscience MassArray system contains custom characteristics that integrated with our genotype database and analytical software which has been developed over the past 10 years and this compatibility is not available from any other source. This system has been optimized in our laboratory for the FUSION study of genes related to type 2 diabetes (Project no. 1Z01HG000024 COLLINS, FRANCIS - Genetic analysis of type II diabetes in Finnish population). Agena Bioscience MassARRAY system include: • The system is capable of delivering up to 140,000 SNP genotypes a day. • Low sample quantity requirements so as to conserve DNA samples. (i.e. a very small amount) • The capacity to genotype up to 36 SNPs on ~20,000 samples (720,000 genotypes) in one week (i.e. a high throughput platform) • Complimentary assay design to share with collaborators • Compatibility with currently existing genotyping equipment at NHGRI/MGS • Compatibility with platform used at the Broad Institute and The Wellcome Trust • Customized database design that is incorporated into the existing MGS LIMS system Period of Performance: Base Year: Twelve (12) months Option Year 1: Twelve (12) months Option Year 2: Twelve (12) months Option Year 3: Twelve (12) months Regulatory Authority: The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-87-2, April 6, 2016. This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13 Simplified Acquisition Procedures (SAP) at the amount not exceeding the Simplified Acquisition Threshold (SAT) under $150,000.00. Statutory Authority: This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1(b)(1), Soliciting from a single source is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13--Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. Additional Information : The acquisition is being conducted under FAR Part 13, simplified acquisition procedures, therefore the requirements of FAR Part 6 B Competitive Requirements are not applicable (FAR Part 6.001). Industry Classification (NAICS) Code is 811219, Other Electronic and Precision Equipment Repair and Maintenance and the Small Business Size Standard is $20.5M. Closing Statement: This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received no later than 7:30 a.m. Eastern Standard Time (EST), May 4, 2016; and must reference synopsis number HHS-NIH-NHLBI-CSB-(HG)-2016-115-DM, may be submitted to the National, Heart, Lung and Blood Institute, COAC Services Branch, Office of Acquisitions, Office of Management, 6701 Rockledge Drive, Suite 6149, Bethesda, Maryland 20892-7902, Attention: Dorothy Maxwell, Contracting Officer. Response may be submitted electronically to maxwelld@mail.nih.gov. Faxes will not be accepted. Responses will only be accepted if dated and signed by an authorized company representative. "All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-(HG)-2016-115-DM/listing.html)
- Place of Performance
- Address: NIH, 50 South Drive, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04094654-W 20160427/160425234415-0b88d88168f0bf303318f16e81ae1bdc (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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