SOURCES SOUGHT
66 -- MICROFLUIDIC MICROSCOPE WORK STATIN
- Notice Date
- 5/3/2016
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Commerce, National Institute of Standards and Technology (NIST), Acquisition Management Division, 100 Bureau Drive, Building 301, Room B130, Gaithersburg, Maryland, 20899-1410, United States
- ZIP Code
- 20899-1410
- Solicitation Number
- AMD-16-SS20
- Archive Date
- 5/25/2016
- Point of Contact
- Lynda M Roark, Phone: 3019753725
- E-Mail Address
-
Lynda.Roark@nist.gov
(Lynda.Roark@nist.gov)
- Small Business Set-Aside
- N/A
- Description
- TITLE: Fluorescence-Capable Microfluidic Microscope Work Station OPDIV: NIST, Center for Nanoscale Science and Technology (CNST) This is a SOURCES SOUGHT NOTICE to determine the availability of potential small businesses (e.g., 8(a), service-disabled veteran owned small business, HUBZone small business, small disadvantaged business, veteran-owned small business, and women-owned small business) in accordance with FAR 7.104(d). The potential small business will need to demonstrate the capability to perform all facets of the work described below. The sole intent of this Sources Sought Notice is to obtain capabilities for set-aside and procurement planning purposes. This is not an invitation for bid, request for proposal, or other solicitation, and in no way obligates the National Institute of Standards and Technology (NIST) to award a contract. BACKGROUND The National Institute of Standards and Technology's (NIST) Center for Nanoscale Science and Technology (CNST) plans to acquire a microfluidic upright compound microscope inspection and measurement station capable of fluorescence detection for optical imaging of "body-on-a-chip" microfluidic platforms in the CNST user facility. The system will be sited in the CNST Nano/MicroBiomedical Measurement Devices Laboratory as a resource for experiments requiring imaging of living tissues in modular microfluidic devices containing nanoscale sensors. It will be accessible to researchers in the CNST and to outside users via collaboration. The research conducted in the Nano/MicroBiomedical Measurement Devices Laboratory requires customizable configurations of the microfluidics work station for specific experimental considerations that will evolve as the research progresses. This customization process includes adding, removing, or exchanging hardware components. In order to increase CNST's capability to serve the biomedical community by development of novel microfluidic platforms for body-on-a-chip applications, NIST has a need for a microfluidic microscope and measurement station capable of fluorescence detection for testing custom-designed and built microfluidic devices with constant flow rate and pressure without damaging or altering the devices. CONTRACTOR REQUIREMENTS To meet the purpose and objective of this requirement, the Contractor shall provide documentation demonstrating the capability to provide a fluorescence-capable microfluidic microscope work station that includes a sample stage, microfluidic pump, delivery system, microfluidic probe, connections, upright microscope, and imaging system with software capable of capturing 2D images and live video. In addition, the offered system shall be capable of meeting or exceeding the salient characteristics below and providing installation of the proposed system on-site at the NIST facility in Gaithersburg, MD. 1. System Configuration. a. The system shall be a stand-alone desktop tool and include the following components: ii. Manual X/Y stage to support samples up to 100 mm diameter or 100 mm on a side. iii. A microscope with zoom range up to 500x and capable of bright field, dark field and epifluorescence. iv. Microfluidic pump(s) and delivery system capable of delivering liquid with constant flow and gas with constant pressure. v. Microfluidic probe and connection system capable of contacting to custom-designed microfluidic devices without damaging or altering the device. vi. Imaging system and software capable of imaging, scanning, live video, 2D measurement and data recording. 2. Microfluidic Probe and Connection System a. The microfluidic probe and connection system shall make adjustable compressive contacts to devices designed and fabricated anywhere without damaging or altering the devices. b. The microfluidic probe and connection system shall allow flexible positioning of samples to accommodate device sizes of irregular shape up to 100 mm in diameter or on a side. c. The microfluidic probe and connection system shall provide non-permanent but tight seal connections to substrate materials including PDMS, silicon and glass. d. The microfluidic probe and connection system shall connect to devices with port sizes ranging from 500 µm to 2 mm. The ability to connect to port sizes less than 500 µm or larger than 2 mm is desirable. 3. Microfluidic pump(s) and delivery system a. The microfluidic pump(s) shall deliver either liquid or gas to the fluidic device. b. The microfluidic pump(s) shall have a total of four channels for gas or liquid. c. The four microfluidic pump channels shall be capable of channel-to-channel communication when under software control. d. The microfluidic pump(s) must deliver flow rates in the range of 0.1 uL/min to 80 uL/min. e. The microfluidic pump(s) shall be programmable and work as a stand-alone pump or be controlled by software. f. The microfluidic pump(s) shall have an integrated flow sensor capable of operating in the range from 0.1 uL/min to 100 uL/min. g. The flow sensor, compressor and microprocessor must all be integrated into the pump(s) for stand-alone operation. 4. Microscope and Imaging System a. The microscope shall have zoom range up to 500x. b. The microscope shall be capable of epifluorescence detection. c. The microscope shall be capable of 2D imaging. d. The microscope must be equipped with a high speed digital camera capable of imaging and video recording at a rate of at least 50 frames per second. Frame rates higher than 50 frames per second are desirable. e. The microscope must be equipped with long-working distance objectives at magnifications of 5X, 10X, 20X, 50X. 5. Data Recording and Image Analysis a. A computer shall be equipped with a Microsoft Windows 7 operation system. b. A computer along with the software shall be integrated with the camera to store and display images and videos. c. The computer along with software shall be integrated with the microfluidic pump(s) to monitor and control the fluid delivery. d. The software shall have stitching capability to form images of a large area of device. e. The software shall be capable of 2D measurements. f. The software shall be capable of real-time image measurement. g. The software shall be able to store and export data. Trade and Service 1. The instrument offered must be new, not a demonstration model nor a refurbished instrument. 2. Vendors should include information regarding warranty availability, duration and coverage. Capability statements must demonstrate the minimum requirements outlined above. Please address each in the order listed above. Please provide the follow Business information: 1. DUNS Number 2. Company Name 3. Company Address. 4. Company Point of Contact, phone number and email address 5. Type of company under NAICS, as validated via the System for Award Management (SAM). Additional information on NAICS codes can be found at www.sba.gov. Any potential government contract must be registered on the SAM located at http://www.sam.gov/index.asp. 6. Corporate structure (corporation, LLC, sole proprietorship, partnership, limited liability partnership, professional corporation, etc.); 7. Current GSA Schedules appropriate to this Sources Sought 8. Current Government Wide Agency Contracts (GWACs) 9. Point of Contact, phone number and email address of individuals who can verify the demonstrated capabilities identified in the responses. Interested parties having the capabilities necessary to provide the stated requirements may submit capability statements via email or regular mail to the point of contact listed below. Responses shall be limited to 10 pages. Responses must be received not later than 3:00PM Eastern Time, May 10th, 2016. Capability statements will not be returned and will not be accepted after the due date. Documentation should be emailed to: Christopher.McGucken@nist.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/DOC/NIST/AcAsD/AMD-16-SS20/listing.html)
- Place of Performance
- Address: 100 BUREAU DRIVE, GAITHERSBURG, Maryland, 20899, United States
- Zip Code: 20899
- Zip Code: 20899
- Record
- SN04103623-W 20160505/160503234826-b2079b972e36221928cc05fbc644eba9 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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