SOURCES SOUGHT
B -- Whole Genome sequencing
- Notice Date
- 6/23/2016
- Notice Type
- Sources Sought
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-2016-448
- Archive Date
- 7/23/2016
- Point of Contact
- Brian Lind, Phone: 301.827.5298
- E-Mail Address
-
lindbj@nida.nih.gov
(lindbj@nida.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Federal Business Opportunities (FBO) SMALL BUSINESS SOURCES SOUGHT NOTICE Solicitation Number: HHS-NIH-NIDA-SSSA- SBSS-2016-448 Title: Human Whole Genome Sequencing Classification Code: Applicable NAICS Code(s): 541990, 541711 & 541712 Description: Whole Genome Sequencing This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The National Institute of Health, National Institute of Mental Health, Human Genetics Branch mission is to determine the human genetic variation that contributes to the risk for mood and anxiety disorders such as bipolar disorder and panic disorder so that better methods of diagnosis and treatment can be developed. Bipolar disorder (BD) is a complex psychiatric disorder that affects 1% of the US population. In order to understand the genetics of this disorder we plan to study homogenous isolated population, the Amish and Mennonites. By performing whole genome sequencing (WGS) of the Amish and Mennonites we aim to identify the causal variants in BD and build a reference panel. This reference panel will be used to infer genotypes in other Amish and Mennonite individuals that are genotyped on single nucleotide polymorphisms (SNP) arrays with high accuracy. Purpose and Objectives: To procure the services for Whole genome sequencing (WGS) of 60 Amish and Mennonite DNA samples. Project requirements: The contractor shall provide the following: 1.Whole-genome library construction for each DNA sample provided 2.Paired end sequencing 3.≥100bp reads 4.Each of the sample provided will have ≥30X coverage for >90% of the human genome Anticipated period of performance: The data and reports should be forwarded within 60 to 90 days after receipt of the DNA samples from NIMH. Other important considerations: The National Institute of Mental Health shall have unlimited rights to and ownership of all deliverables provided under this contract, including reports, recommendations, and all deliverables. This includes the deliverables provided under the basic contract and any DNA remaining after library construction, unless contractor is notified in writing by the contracting officer that remaining DNA samples may be destroyed. In addition, it includes any additional deliverables required by contract change. The definition of "unlimited rights" is contained in Federal Acquisition Regulation (FAR) 27.401, "Definitions." FAR clause 52.227-14, "Rights in Data-General, " is hereby incorporated by reference and made a part of this contract/order. The DNA samples provided and the data generated by the sequencing company are the sole property of the Human Genetics Branch, National Institute of Mental Health, National Institutes of Health (NIH), Bethesda,, MD, USA Capability statement /information sought: Respondents capability documents should include information regarding the following': (a) Staff expertise, including their availability, experience, and formal and other training; (b) Current in-house capability and capacity to perform the work; (c) Prior completed projects of similar nature; (d) corporate experience and management capability; and (e) Examples of prior completed Government contracts, references, and other related information; The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Brian Lind at e-mail address lindbj@nida.nih.gov. The response must be received on or before July 8, 2016 at 9:00AM Eastern Time. "Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SBSS-2016-448/listing.html)
- Place of Performance
- Address: To be performed at contractor's facility, United States
- Record
- SN04160046-W 20160625/160623234923-b51fa3677b6e31402e71fdabfe74893d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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