SOURCES SOUGHT
70 -- Alcohol Vapor System
- Notice Date
- 7/26/2016
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SS-2016-588
- Archive Date
- 8/19/2016
- Point of Contact
- Pamela J. Daugherty, Phone: 3014802467
- E-Mail Address
-
pamela.daugherty@nih.gov
(pamela.daugherty@nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- INTRODUCTION This is a Small Business Sources Sought (SBSS) notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability and type of qualified Small Business companies technically capable of meeting this potential government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. The notice is strictly for research and information purposes only. The information requested will assist the Government in determining the appropriate acquisition method including small business socio-economic set-aside possibilities and to determine the availability of qualified Small Business companies technically capable of meeting the Government's potential requirement. All Small Business companies with the capability and availability to perform the requirement under the applicable NAICS code are invited to submit a response to this notice. NORTH AMERICAN CLASSIFICATION SYSTEM (NAICS) CODE The NAICS code applicable to this requirement is 334516 -- Other Scientific and Technical Consulting Services-- with associated business size standard of 1,000 employees BACKGROUND The National Institute on Drug Abuse, Neurobiology of Addiction section is studying the neurobiology of alcohol dependence. Alcohol dependence is a complex psychiatric condition characterized by craving, compulsive drug seeking, excessive drug taking, and the emergence of negative emotional states during withdrawal. We have developed animal models that produce signs of drug dependence that strongly resemble the human condition. Rats are made dependent on alcohol by chronic, intermittent alcohol vapor exposure. Dependent rats escalate their alcohol intake over the course of vapor exposure. Air exposed rats exhibit stable intake levels and serve as nondependent controls (air or nondependent). Using these models, we investigate the neurobiology of alcohol dependence through the use of drugs that stimulate or block different neuronal messenger (neurotransmitter) molecules in the brain. PURPOSE AND OBJECTIVES The purpose of this acquisition is to acquire an alcohol vapor system to allow us to study the neurobiology of alcohol dependence and reach the goals of our laboratory. PROJECT REQUIREMENTS One Custom Six Chamber Alcohol Vapor Inhalation system. The specifications are further outlined below: • These chambers must allow one to very precisely control the concentration of alcohol in the air to produce different levels of alcohol exposure to induce a wide range of biological changes to be systematically studied. The blood alcohol level in the rat can be increased progressively from 0 to 250 mg/dl. Importantly, they must allow intoxication levels to be tightly controlled to preserve animal health. The alcohol pump speed varies from 0 to 360 strokes per minute. Usual range 5-25 strokes per minute. • Each chamber must have an integrated sampling system to monitor the concentration of vapor in the air. Operating system includes alcohol sensor that will turn off alcohol pump if alcohol concentration reaches pre-set limits. • The alcohol inhalation chambers must have a double-chamber containment system that guarantee that the experimenter is safe of any hazardous vapor exposure at all time. Therefore, even if the experimenter forgets to close the rat chamber or do it improperly resulting in air leakage the double containment will ensure that the room where the system in, is not contaminated. • Custom 6-chamber alcohol vapor inhalation system. Each chamber must accommodate a large cage ("jumbo cage 2100") with AALAS space requirements for three rats over 500. • The chamber must include a complete automation and operating software on touchscreen tablet. • Operating system can run pre-set or customized exposure parameters. • The alcohol inhalation chambers must have a double exhaust system that provides negative pressure inside the first containment chamber so that no vapor escapes the system when the doors are open. Guaranteeing again the safety of the experimenter. Other commercially available systems have only one exhaust without containment chamber with negative pressure. • Includes two air compressors with alternating switch and alarm system that will notify investigator via text/phone in the event of an air compressor failure. Must be IACUC and AAALAC certified Period of Performance: The anticipated delivery date for this acquisition is 60 days ARO. CAPABILITY STATEMENT / INFORMATION SOUGHT Interested parties are expected to review this notice to familiarize itself with the requirements of this project. Failure to do so will be at your firm's own risk. Respondents must provide clear and convincing evidence of their capability to analyze samples described in this announcement on a deep sequencing system capable of achieving the scale described in this announcement. Detailed past experience in implementing similar requirements to the requirement described in this announcement must be clearly delineated in any response provided, including items delivered; Evidence of any published manuscripts or other documentation produced shall be used to support past experience. Respondents must provide clear and convincing documentation of their capability in providing analytical quality control and any other requirements and services specified in this notice. Respondents must provide a general overview of the respondents' opinions about the difficulty and /or feasibility of the potential requirement, and any information regarding innovative ideas or concepts. The Respondent must also provide information in sufficient details of the respondents' (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information. The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc.) pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be must be in and outline format that addresses each of the elements of the product requirement. A cover page and an executive summary may be included but is not required. The response is limited to 15 pages. The 15-page limit does not include the cover page, executive summary, CV's or references, if requested. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Pamela Daugherty at pamela.daugherty@nih.gov prior to the closing date specified in this announcement. The response must be received on or before August 4, 2016 at 3:00 pm, Eastern Time. CONCLUDING STATEMENTS Disclaimer and Important Notes. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SS-2016-588/listing.html)
- Place of Performance
- Address: Biomedical Research Center, 251 Bayview Blvd, Baltimore, Maryland, 21224, United States
- Zip Code: 21224
- Zip Code: 21224
- Record
- SN04196564-W 20160728/160726235221-404bb0c5900a55412fa9a96c4dda9b8d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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