SOURCES SOUGHT
66 -- Small Animal PET/CT Imaging System
- Notice Date
- 7/27/2016
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-EB-2016-SBSS-236-CB
- Archive Date
- 8/26/2016
- Point of Contact
- Chris Bocus, Phone: 3014027888
- E-Mail Address
-
chris.bocus@nih.gov
(chris.bocus@nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- Introduction This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under NAICS code 334516 should not submit a response to this notice. Background The National Heart, Lung and Blood Institute (NHLBI) on behalf of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is seeking small businesses with the ability to provide a small animal PET/CT imaging system fulfill the preclinical research of the imaging probe development in the Laboratory of Molecular Imaging and Nanomedicine (LOMIN). The Laboratory of Molecular Imaging and Nanomedicine (LOMIN), NIBIB does research to identify disease-specific biomarkers, to develop new molecular imaging probes, to apply newly developed probes in multimodality imaging, and to characterize novel imaging and therapeutic agents, both in vitro and in vivo. One important research direction of LOMIN is to develop novel methods to incorporate radionuclides into molecules for the study of biologically important processes by non-invasive PET imaging. Our research efforts are driven by a desire to better understand human biology, and disease and to generate tools that have clinical implications. We design probes with applications to many important biological processes. Therapeutic efficacy is a key question that needs to be answered for every drug or drug candidate. Molecular imaging is able to provide information to evaluate pharmacological effects. For instance, solid tumors are often characterized by having high glucose utilization, tumor cell proliferation, hypoxia with sustained angiogenesis and evasion of apoptosis. The influence of compounds targeting these characteristics of cancer biology can be selectively visualized by molecular imaging techniques, especially by PET imaging. Examples include FDG PET to image glucose transport and metabolism, and FLT PET to evaluate proliferation status. Additionally, we will apply the novel PET imaging probes targeting one particular pathway such as apoptosis and hypoxia or a single molecular target to access specific drugs. Project Requirements The Contractor is expected to provide the one (1) small animal PET/CT system with following equipment requirements and specifications: General Specifications: 1. A high sensitivity, high resolution and fully integrated small animal PET/CT system supports imaging of a wide range of animal species; from mice to monkeys. 2. High throughput imaging capacity to perform PET/CT for a relatively large cohort of experimental animals. 3. Upgradable to a trimodality system to include SPECT if needed. 4. Closed, temperature controlled imaging cells integrated with physiological monitoring system and anesthetic gas connection 5. Respiratory and cardiac gating ability 6. Multi GPU image reconstruction 7. Installation and calibration of the system; on-site training 8. One year warranty Specific Requirements: PET Stationary ring system Pixelated LYSO scintillator matrix Flat panel photomultiplier tube 15-17 cm inner bore size 11-13 cm transaxial field of view (TFOV) Energy resolution > 18% Time resolution < 1.3 ns List mode acquisition Absolute quantification accuracy >95%. Greater than or equal to 7% sensitivity with a 250-750 keV energy window CT 35-80 kV X-ray generator Flat panel CMOS detector Adjustable magnification no less than 7 Spacial resolution less than 30 microns Capability Statement Small business concerns that believe they possess the capabilities necessary to address this requirement should submit complete documentation of their capabilities to the Contracting Officer. The capabilities statement must specifically provide equipment that addresses each specification and/or requirement listed above. Additionally, the capability statement should include 1) the total number of employees, 2) an outline of previous equipment supplied to similar organizations, and 3) any other information considered relevant to this requirement. The capability statement must not exceed 7 single sided or 3.5 double sided pages in length and using a 12-point font size minimum. Interested small business organizations are required to identify their size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone numbers of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. Point of Contact: Primary: Chris Bocus, Contracting Officer, NHLBI COAC Services Branch, Phone (301) 402-7888, Fax (301) 402-7888. Secondary: Arun Mathur, Contract Specialist, NHLBI COAC Services Branch, Phone (301) 451-8045, Fax (301) 402-7888. Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions 6701 Rockledge Dr RKL2/6016 MSC 7902, Bethesda, MD, 20892-7902, UNITED STATES Submission Instructions: Interested parties shall submit capability statements via the FedConnect web portal (www.fedconnect.net) and reference the FedConnect Sources Sought Number HHSN268 16EB00006S. The due date for receipt of statements is 2 pm Eastern Time on August 11, 2016." Vendors can register with FedConnect at https://www.fedconnect.net/FedConnect/default.htm. Please note that FedConnect is used by multiple federal agencies and therefore FedConnect assistance will be provided by Compusearch Software Systems, not the NHLBI OA. More information about registration requirements can be found by downloading the FedConnect Ready, Set, Go! Guide at https://www.fedconnect.net/fedconnect/Marketing/Documents/FedConnect_Ready_Set_Go.pdf. For assistance in registering or for other FedConnect technical questions please call the FedConnect Help Desk at (800) 899-6665 or email at support@fedconnect.net. Please use the Contracting Officer/ Contract Specialist contact information provided, should you require a waiver not to use FedConnect for submitting. All responses must be received by the specified due date and time in order to be considered. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-EB-2016-SBSS-236-CB/listing.html)
- Place of Performance
- Address: Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04197834-W 20160729/160727234705-3fb3025768deccabbd96a0c9015b69f2 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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