SOLICITATION NOTICE
R -- Custom SomaScan Analysis of 160 Plasma Samples from Pima Indians
- Notice Date
- 8/4/2016
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Child Health and Human Development, Contracts Management Branch, 6710B Rockledge Dr., Suite 1124, MSC7000, Bethesda, Maryland, 20892-7510, United States
- ZIP Code
- 20892-7510
- Solicitation Number
- NIH-NICHD-16-135
- Archive Date
- 8/24/2016
- Point of Contact
- Amber Harris, Phone: 3014028778
- E-Mail Address
-
amber.harris@nih.gov
(amber.harris@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NIH-NICHD- 16-135 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-78. The North American Industry Classification (NAICS) Code is 541380 and the business size standard is $15.00. The National Institutes of Health (NIH), National Institute of Digestive, Diabetes & Kidney Diseases (NIDDK) intends to award a purchase order to Joslin Diabetes Center & Joslin Clinic, One Joslin Place, Boston, MA 02215. This is pursuant to 41 U.S.C. 253(c)(1)-Only one responsible source and no other supplies or services will satisfy agency requirements. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Phoenix Epidemiology and Clinical Research Branch (PECRB) reported recently that serum tumor necrosis factor receptors 1 and 2 (TNFR1 and TNFR2) are strongly associated with the progression of diabetic kidney disease in type 2 diabetes. The PECRB then reported a strong relationship between serum TNFR1 and TNFR2 concentrations and the structural lesions of diabetic kidney disease. Most recently, Investigators at the Joslin Clinic observed that 14 other ligands and receptors of the TNF superfamily were strongly associated with a high risk of kidney failure in 110 patients with type 1 diabetes during 7-15 years of follow-up. The PECRB wishes to determine which of these candidate proteins are risk factors and which are just correlates or markers of disease progression in type 2 diabetes. To do so, the PECRB needs to measure the candidate proteins in a larger sample of persons with type 2 diabetes in whom kidney disease is well characterized. The purpose of this requirement is for the Phoenix Epidemiology and Clinical Research Branch (PECRB) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to procure services allowing them to measure 560 candidate proteins in plasma obtained from 160 Pima Indians with type 2 diabetes on a custom-made SomaScan platform located at the Joslin Clinic. The results of these measurements will be used to identify the underlying mechanisms by which the TNF superfamily is influencing the progression of diabetic kidney disease and whether these mechanisms differ in type 1 and type 2 diabetes. The Pima Indians are ideal for this purpose because of the extensive characterization of kidney disease in this cohort over the past 30 years and the absence of other health conditions that could interfere with this assessment. Candidate proteins in the type 1 diabetes cohort from the Joslin Clinic were measured on a SomaScan platform and for comparison purposes, the samples from the type 2 diabetes cohort need to be measured on the same instrument. Offers will also be evaluated on best value in relation to price. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certification-Commercial Items, with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of providing the required/actual equipment in this synopsis should submit a copy of their quotation to the below address or via email to amber.harris@nih.gov. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties, and/or other information that demonstrates that the offer meets all of the foregoing requirements. Quotations will be due five (5) calendar days from the publication date of this synopsis or by August 9, 2016 by 10:00am EST. via email. The quotation must reference Solicitation number NIH-NICHD-16-135. Quotations sent by postal mail or other mailing services must be submitted to the following address: Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710 Rockledge Drive, Room 1159A, Bethesda, MD 20817 Attention: Amber Harris, by the date and time mentioned above. Any questions must be sent via email to amber.harris@nih.gov and must include Solicitation number NIH-NICHD-16-135 in the subject line of email. Faxed copies/responses will not be accepted. PLEASE NOTE: In order to receive an award, contractor must be registered and have valid certification in the System for Award Management (SAM) http://www.sam.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NICHD/NIH-NICHD-16-135/listing.html)
- Place of Performance
- Address: Phoenix, Arizona, United States
- Record
- SN04209893-W 20160806/160804235355-0e218cd3adfee0bf011e4bfe958ca6bd (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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