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FBO DAILY - FEDBIZOPPS ISSUE OF SEPTEMBER 01, 2016 FBO #5396
SOLICITATION NOTICE

68 -- Custom Exendin-4 Peptide

Notice Date

8/30/2016
 

Notice Type

Presolicitation
 

NAICS

325199 — All Other Basic Organic Chemical Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 

ZIP Code

20892-7902
 

Solicitation Number

NHLBI-CSB-EB-2016-297-KEW
 

Archive Date

9/21/2016
 

Point of Contact

Kyle Wisor, Phone: 3014023670, Chris Bocus, Phone: 3014027888
 

E-Mail Address

Kyle.Wisor@nih.gov, chris.bocus@nih.gov
(Kyle.Wisor@nih.gov, chris.bocus@nih.gov)
 

Small Business Set-Aside

N/A
 

Description

INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA) on behalf of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), intends to negotiate and award a Purchase Order without providing for full and open competition (Including brand-name) to C S Bio, 20 Kelly CT, Menlo Park, CA 94025 for custom made Exendin-4 Peptides. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 325199, All other basic organic chemical manufacturing, with a Size Standard of 1,000 employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 05-89 effective 15 AUG 2016. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($150,000). STATUTORY AUTHORITY This acquisition is conducted under the authority of 41 U.S.C. 253(c) under provisions of the statutory authority of FAR Subpart FAR 6.302-1-Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1). DESCRIPTION OF REQUIREMENT Background The National Institutes of Health (NIH) is the nation's leading medical research agency, and the primary Federal agency conducting and supporting medical discoveries that improve people's health and save lives. The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve health by leading the development and accelerating the application of biomedical technologies. The Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. The Laboratory of Molecular Imaging and Nanomedicine (LOMIN) at NIBIB does research to identify disease-specific biomarkers, to develop new molecular imaging probes, to apply newly developed probes in multimodality imaging, and to characterize novel imaging and therapeutic agents, both in vitro and in vivo. Using a multidisciplinary approach, LOMIN builds new systems for various biomedical applications ranging from the medical use of peptide-based diagnostic agents, to therapeutic agents, and even possible future applications of theranostics (diagnosis + therapy). The LOMIN is producing Evans blue dye conjugate from custom peptides for treatment of type-2 diabetes in db/db mice and cynomolgus monkeys. The NIBIB has a requirement for more custom made Exedin-4 peptides to continue the current research. Purpose and Objectives The purpose of this contract is to procure custom made Exedin-4 peptides for use in the construction of chemical analogs for testing in biological systems for imaging and therapy applications. The objective of this protocol is to continue the current research involving the peptides and scale up the synthesis and test the compound in more mice and primates to obtain statistically significant results. Project Description The contractor shall provide the following product: 1: Product name: C S BIO Exendin-4; Description: custom peptide; Quantity: 20 grams Delivery: Overnight Shipping upon receipt of award National Institutes of Health, NIBIB 10 Center Drive Building 10 Bethesda, MD 20892 CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION Only one source is available; the determination by the Government to make a single-sole source is based upon the market research conducted as prescribed in FAR Part 10- specifically the results of the Sources Sought notice NHLBl-CSB-EB-2016-274-KEW posted 8/19/16 that C S BIO is the sole contractor capable of providing the required custom peptides, no other vendor provided a capability statement. C S Bio does not authorize 3rd party resellers to distribute the Exendin-4 Peptide, C S Bio is the sole source provider. The Peptides are unique because C S BIO customizes standard Exendin-4 Peptides by adding to the formula, the custom formula is proprietary to C S BIO. The LOMIN lab needs to continue using this formula to keep results consistent with prior year results. Use of a different formula will invalidate current research data and compromise the comparisons to prior year research. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by 9/6/16 0900 EST and must reference number NHLBI-CSB-EB-2016-297-KEW. Responses may be submitted electronically to Kyle Wisor, Kyle.Wisor@nih.gov, or by U.S. mail to the National Heart, Lung, and Blood Institute, Office of Acquisitions, COAC Services Branch,6701 Rockledge Drive, Suite 6150B, Bethesda, MD 20892-7902, Attention: Kyle Wisor. Fax responses will not be accepted. "All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency."
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-CSB-EB-2016-297-KEW/listing.html)
 

Place of Performance

Address: National Institutes of Health, NIBIB, 10 Center Drive, Bethesda, Maryland, 20892, United States

Zip Code: 20892
 

Record

SN04248222-W 20160901/160831000524-79d019f649e9579a8a46918e6f9c9cdd (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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