SOLICITATION NOTICE
66 -- Two-photon Laser Scanning Microscope System Brand Name or Equal Bruker Nano - 52.212-5
- Notice Date
- 9/13/2016
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-CSS-2016-760
- Archive Date
- 10/1/2016
- Point of Contact
- Hunter A. Tjugum, Phone: 301 435 8780
- E-Mail Address
-
hunter.tjugum@nih.gov
(hunter.tjugum@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- 52.212-5 (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is HHS-NIH-NIDA-SSSA-CSS-2016-760 and the solicitation is issued as a Request for Quotation (RFQ) on a full and open competitive basis with no set-aside restrictions. This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold of $150,000.00. A fixed-price type contract is contemplated for any resulting contract entered into as a result of this solicitation. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC Number/Effective Date: FAC 2005-89-1 / 08-15-2016. (iv) The North American Industry Classification System (NAICS) code for this procurement is 334516 - Analytical Laboratory Instrument Manufacturing with associated business size standard 1000 employees. (v) Background The National Institute of Mental Health (NIMH) Laboratory for Functional Neural Circuits focuses on how different brain states modulate sensory representation in the brain. To conduct reseearch, the laboratory uses the rodent whisker system as a model for studying top-down modulation of sensory processes because both motor and sensory processes are tightly related behaviorally and anatomically. The laboratory follows a multidisciplinary approach that combines electrophysiological, imaging, and optogenetic methods in vivo. To monitor specific populations of neuronal activity during different behavioral states, the laboratory has a requirement for a two-photon laser scanning microscope system in accordance with the essential features and specifications described in this solicitation. Purpose and Objective: The purpose of this acquisition is to obtain the required supply and delivery described in this announcement; specifically: one (1) Two-Photon Laser Scanning Microscope System on a BRAND NAME OR EQUAL basis for the Ultima Investigator DL Laser Scanning Microscope System with operational accessories manufactured by Bruker Nano, Inc FMBU, located at 3030 Laura Lane, Middleton, WI 53562. Product Description: Products offered must include those salient physical, functional, or other characteristics of the Laser Scanning Microscope system and operational accessories by Bruker Nano, Inc. that are deemed essential in meeting the government's needs. Specifically, the following are considered essential requirements for this acquisition: 1) Subject requirement must have integrated rotation in objective nosepiece. The brain area of study is the primary somatosensory cortex. In order to image this area, it requires rotation in the objective nosepiece. 2) Optogenetic manipulation (470/594nm full fiend illumination module). In order to manipulate specific population of neurons, the system requires optogenetic manipulation (470/594nm full fiend illumination module) while performing electrophysiology and calcium imaging in vivo. To perform simultaneous optogenetic manipulation and calcium imaging, it requires sequential full field photoactivation with LEDs and scanning. Software for data acquisition MUST allow for simultaneous optogenetic manipulation and calcium imaging. Must provide optogenetic information and data to support subject manipulation specifications. 3) High-speed shutters and controller. Photo-activation can be performed rapidly while imaging when high-speed shutters and controller are used. High-speed shutters are also important to protect the detectors from exposure to any photo-activation light. Must contain shutters on PMTs; mechanical shutter in front of the PMT photocathode to help avoid exposing the photocathode to the optogenetic light. 4) Drive for volume imaging of 3D populations. To simultaneously image neuronal activity across different layers in cortex, it requires imaging neuronal activity at different spatial scales in three dimensions at high temporal resolution. It will require volume imaging of 3D populations with 400um as well as 1000um travel range. 5) Resonant scanner. To achieve high temporal resolution of neuronal activity, scanning require 30 frame per second. Must have resonant scanner AND galvo scanning for imaging as is required for dynamic ROIs using the x-galvo to reposition the center of the resonant scan. Products offered must be essentially equal to the specified high throughput microscope slide imaging system described in this solicitation that specifically includes the Bruker Nano Ultima Investigator DL Laser Scanning Microscope with the following model, quantity and technical specifications and essential features. INV-02 1: A multiphoton imaging system on an upright in vivo base with scanner, base and platform designed to include a single set of galvanometers to provide raster scan imaging. Configured specifically for in vivo imaging. Additional operational accessories include: 6mm X-Y galvanometer pair; Dual close-proximity detectors; Prairie View scan control and image collection software. INV-MB 1 Upgrade to Moving X-Y Platform for Ultima Investigator X-Y translation base for Ultima Investigator system. Includes motors and translation optics. INV-RG 1 Resonant Scanner High-Speed Optics Set for Ultima Investigator to include: 8kHz resonant galvanometer; High-speed (30fps) scan electronics controller; Lens relay system; Scan head modified for resonant scanner entry path; Prairie View Resonant Galvo + software module. INV-Up-2 1 Upgrade of Both Multi-Alkali PMTs to GaAsP for Ultima Investigator (0MA and 2 GaAsP Total) to include: Two GaAsP tubes, Hamamatsu Model H10770 with mounting Flanges; Pre-Amplifier control for GaAsP tubes. INV-HSS 2 High-Speed Shutter for Ultima Investigator. High-speed shutter to protect PMTs from light pulses. INV-10770-mount 2 High-Speed Shutter Mount for Ultima Investigator with Hamamatsu 10770 PMT. Mount to attach high-speed shutters to 10770 PMTs on an Ultima Investigator. 518708 1 High-Speed Shutter Controller. Controller for high-speed shutters placed in front of PMTs to protect the detectors from light pulses. Controller can regulate up to four shutters per unit. Includes lamp house interlock cable. INV-FF-470/594 1 470/594nm Full Field Illumination Module for Ultima Investigator. LED diode illumination system centered at 470nm and a second LED at 594 for illumination of the full visible field for optogenetic stimulation of channel Rhodopsin. Device is fully integrated into software to deliver pulses of light at controlled intensities synchronized with imaging protocols. N-6563 1 Nikon Objective: CFI75 16X/0.80 WD=3mm. Requires single objective holder. 519601 1 Z-Axis Piezo Drive for Ultima - 400um. M32 Threaded objective lens holder with piezo-electric elements enclosed. Allows for high speed z-positioning of objective lens. 400 um range. Capacitance feedback algorithm used with positioning accuracy of 25nm. U-0962 1 Epi-Fluorescence Light Source - X-Cite 120 for Nikon. 518065 1 Epi-Fluorescence Filter Set: ET-GFP (FITC/CY2) for Nikon. 518066 1 Epi-Fluorescence Filter Set: ET-DSRed (TRITC/CY3) for Nikon. N-0963 1 Epi-Fluorescence Filter Set: UV-2E/C DAPI for Nikon for fluorescence viewing via the eyepieces. U-IMP-1 1 Laser Input Optics with Pockels Cell - Imaging (115VAC). Optics to route and attenuate an ultra-fast laser for scanner imaging path. Includes: Mounted beam splitting cube and 1/2 wave plate; Laser beam trap; Pockels cell with >500:1 extinction ratio for high-speed shuttering and continuous power control of imaging laser; 115V; Pockels cell mount; Alignment target for Pockels cell; Mirrors and irises to efficiently couple the imaging laser to scanner; Table-mounted mechanical shutter. Install-16 1 Installation and Training - Single Laser Input. Installation and training in the operation of the system. Installation of a single scan head with one laser input. Contractor shall possess the ability to achieve the essential requirements described in this solicitation. Inspection and Acceptance Offerors should indicate an estimated delivery time in full after receipt of an order and any other training or warranty schedules applicable. Inspection and acceptance will be performed at the National Institutes of Health, National Institute on Mental Health, located at 35 Convent Drive, Bethesda, MD 20892. The Government expected delivery and installation timeframe is 150 days after contractor receipt of any contract resulting from this solicitation. (vi) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. The following is provided as an addendum to FAR clause 52.212-1, Instructions to Offerors. Offerors should indicate an estimated delivery time in full after receipt of an order and any other training or warranty schedules applicable. (vii) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. The following is an addendum to 52.212-2. Responses received to this RFQ will be evaluated on the basis of Lowest Price Technically Acceptable (LPTA). Offeror's submitting a response must provide a completed Price Quote to be evaluated and considered for award. Price quotes must indicate fixed unit pricing and total cost, including shipping cost and estimated time of delivery after receipt of order, and warranty and training considerations. Responses will be evaluated based on contractor's ability to meet the government's essential requirements stated in this notice and on ability to deliver required supplies. Responses to this solicitation must include clear and convincing evidence of the Offeror's capability of fulfilling the requirement as it relates to the essential government requirements stated in this solicitation. Under the lowest-price technically acceptable (LPTA) process, Offerors' will be determined to be "technically acceptable" or "technically unacceptable" based on an evaluation of responses against the following factors to determine if, as submitted, the proposal is technically acceptable. (1) Technical Capability: Offerors shall clearly indicate possessing the capability to achieve the essential features of this requirement. Offerors submitting a response with documented technical specifications and evidence of possessing the technical knowledge, qualifications and capability and management structure needed in successfully achieving this requirement will be determined to be technically acceptable. Award will be made to the lowest-priced, technically acceptable, responsible offeror. Technical acceptability shall be based on the following Subfactors: 1) The Offeror must indicate in its quotation the ability to provide all of the requirements; 2) The Offeror must indicate in its quotation the ability to meet the delivery requirements. Respondents that believe that they are manufacturers or authorized resellers of the BRAND-NAME product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. (viii) The provision at FAR Clause 52.212-3, Offeror Representations and Certifications Commercial Items, applies to this acquisition. (ix) The provision at FAR Clause 52.212-4, Contract Terms and Conditions-Commercial Items, applies to this acquisition. An addendum to FAR Clause 52.212-4, Contract Terms and Conditions-Commercial Items, Offeror Representations and Certifications Commercial Items, applies to this acquisition. (x) The provision of FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition and is incorporated into this solicitation as an attachment. (xi) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xiii) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria and a price proposal. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer, or provide a copy of the valid certifications registrations and Representation and Certifications from the System of Award Management (SAM) applications at www.SAM.gov, which may be indicated on the Offeror's cover sheet. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received no later than the date specified in this announcement. Late responses will not be accepted. All responses must reference solicitation number HHS-NIH-NIDA-SSSA-CSS-2016-760. Responses must be submitted electronically to hunter.tjugum@nih.gov and NIDASSSAPurchaseRequ@mail.nih.gov. Facsimile responses will not be accepted. For information regarding this solicitation, contact Hunter Tjugum by email at hunter.tjugum@nih.gov or by phone at 301-827-5304.
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