DOCUMENT
A -- Sources Sought for Affymetrix Axiom Precision Medicine Array testing. - Attachment
- Notice Date
- 2/6/2017
- Notice Type
- Attachment
- NAICS
- 621511
— Medical Laboratories
- Contracting Office
- US Department of Veterans Affairs;Veterans Health Administration;Service Area Office (SAO) East;323 North Shore Drive, Suite 500;Pittsburgh PA 15212-5319
- ZIP Code
- 15212-5319
- Solicitation Number
- VA24017N0085
- Response Due
- 2/9/2017
- Archive Date
- 2/12/2017
- Point of Contact
- Jeffrey M Greis
- E-Mail Address
-
y.greis@va.gov<br
- Small Business Set-Aside
- N/A
- Description
- The Research & Development Service at the Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA 30033, has a requirement for Affymetrix Axiom Precision Medicine Array testing (PMRA). The SAO East R&D Contracting Office intends to negotiate on a sole-source basis with AKESOgen, a small business, 3155 Northwoods Place, Norcross, GA 30071 for this procurement/processing of 96 samples because the Government believes that only AKESOgen has the GeneTinan MC instrument to run the array, including an axiom analysis suite and affymetrix gene chip command console software needed for the analysis- all in a manner consistent and compatible with the testing methodology and benchmarking already performed under on ongoing Genome Study. Salient Characteristics: GWAS variants The array includes a genome-wide imputation grid with about 800,000 markers. The GWAS module has been designed to cover the five ancestral population groups [African (AFR), admixed American (AMR), East Asian (EAS), European (EUR), and South Asian (SAS) ancestry] with the highest mean r2 genomic coverage across all ancestral populations. Clinically actionable variants This module includes clinically relevant variants from ClinVAR and enables assessment of actionable genetic risk across a wide range of populations. Immune-related markers Markers were chosen to cover immune function as well as autoimmune diseases and inflammatory diseases and response. This includes human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) markers and variants were included that show evidence for association with specific autoimmune and inflammatory disorders. Functional variants Includes loss of function markers selected from biobank arrays as well as human disease mutation and exome databases. Markers were included to support mapping functional non-coding variations to identify genetic markers associated with gene transcription variability and differential gene expression. Fingerprint/sample tracking variants Axiom PMR includes over 300 variants for sample tracking and fingerprinting to eliminate any sample contamination during analysis. These variants have been successfully used in large biobank studies to ensure sample integrity during analysis. This notice of intent is not for competitive quotes. The North American Industry Classification System (NAICS) number is 621511, small business size standard of $32.5 million. This notice is NOT a request for competitive proposals and no solicitation document is available. However, parties may express their interest accompanied by supporting literature by email to Jeff Greis, Contracting Officer, no later than February 9, 15:00 ET. Responses should be sent to jeffrey.greis@va.gov. No telephone responses will be accepted. Information received will be for the purpose of determining whether or not to conduct a competitive procurement or proceed with a sole-source procurement. The determination to conduct a competitive procurement based on responses to this notice is solely within the discretion of the VAPHS Contracting Officer. Please include your socioeconomic status (i.e., SDVOSB, VOSB, etc.) and DUNS numbers in your responses.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/notices/e7f88fb100ad950388f74c4f5f1e3c43)
- Document(s)
- Attachment
- File Name: VA240-17-N-0085 VA240-17-N-0085.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3255557&FileName=VA240-17-N-0085-000.docx)
- Link: https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3255557&FileName=VA240-17-N-0085-000.docx
- Note: If links are broken, refer to Point of Contact above or contact the FBO Help Desk at 877-472-3779.
- File Name: VA240-17-N-0085 VA240-17-N-0085.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3255557&FileName=VA240-17-N-0085-000.docx)
- Place of Performance
- Address: VA Atlanta Medical Center;Research Service;1670 Clairmont Rd.;Decatur, GA
- Zip Code: 30033
- Zip Code: 30033
- Record
- SN04392685-W 20170208/170206235524-e7f88fb100ad950388f74c4f5f1e3c43 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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