SOLICITATION NOTICE
66 -- UPLC Ultra High Resolution Mass Spectrometer
- Notice Date
- 5/4/2017
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- CPOD US Environmental Protection Agency 26 West Martin Luther King Drive Mail Code: NWD Cincinnati OH 45268 USA
- ZIP Code
- 00000
- Solicitation Number
- SOL-CI-17-00033
- Response Due
- 5/19/2017
- Archive Date
- 9/28/2017
- Point of Contact
- Loesch, Kimberly
- Small Business Set-Aside
- N/A
- Description
- The U.S. EPA intends to negotiate on a sole source basis, under the authority of FAR 6.302-1(b)(1)(i), with Thermo Electron North America, LLC for an Orbitrap Fusion IC which is an ultra-high pressure/performance liquid chromatography (UPLC) system coupled with an ultra high resolution mass spectrometer (HRMS). The EPA requires a UPLC coupled with an HRMS (>200,000 resolving power) capable of real-time isolation of precursor and fragmentation trees of fragment ions (MSn) for non-targeted analysis of emerging chemicals of concern in environmental media. The minimum specifications for the UPLC-HRMSn are as follows: 1.The complete instrumentation package will consist of: a.An ultra-high pressure/performance liquid chromatograph (UPLC) capable of binary flows, from 50 micro L/min to 2 mL/min via software control b.An autosampler capable of holding small (2mL) sample vials c.And a HRMSn capable of high resolution (>200,000) accurate mass (<2 ppm) and MSn capabilities. d.OEM Software capable of deconvolution of spectra in complex environmental/biological media and reduction of large data sets that result. 2.System control, data acquisition, and data processing shall be accomplished by vendor software on computer(s): embedded fast data collection computer, dedicated instrument control computer, and high-speed data processing computer workstation; the computers should be configured/or compatible with Microsoft Windows 7 Professional 64-bit, Service Pack 1 or higher. These computer system(s) must be able to communicate and share data at rates comparable with the data collection rates of the mass spectrometer. If multiple computers are required they will be networked to allow communications, instrument control, and data processing for all modes of mass spectrometer operation. 3.A minimum resolution of 200,000 needed for fine isotope structure elucidation of precursor compounds spectra. 4.A minimum resolution needed of 200,000 for fine isotope structure of daughter ions. 5.Maximum resolution of >400,000 for almost unequivocal identification of mass spectra formula prediction. 6.Duty cycle >10 Hz for non-targeted screening in complex mixtures. 7.Mass accuracy <1 ppm for internal mass calibration to limiting false positive formula predictions. 8.The ability to capture precursor ions and fragment for daughter ions with conserved HRMS resolution for structure elucidation. 9.A multi-ionization source, multiple detector and multiple fragmentation mode capable platform to allow optimization for multi- media and chemical analysis. 10.Potential for simultaneous acquisition of high (>200,000) and low resolution (<20,000) data for targeted screening and compound elucidation at the same time. 11.Adequate on-column sensitivity (<500 fg on column) for analysis of trace level samples. 12.No need for specialized equipment (for example liquid nitrogen or argon cryogenic gas requirements for operation) or room modifications for normal operation. 13.A fully functional, factory refurbished HRMSn could meet these aforementioned requirements. 14.Training on use of equipment for (at least 2) individuals at USEPA Facility in Research Triangle Park, NC. 15.All electrical needs must be compatible with standard US electrical outlets, i.e., 230 VAC + or - 10% single phase, 15 A, 50/60 Hz, with earth ground, and/or 120 VAC single phase with earth ground. 16.The instrument should be capable of being operated using high purity nitrogen, including activation of valves etc. 17.Instrument should be considered "bench-top" or fit on a floor space with dimensions no greater than the following: 125 cm (H) x 185 cm (W) x 100 cm (D) in a room with no needed HVAC alterations. 18.A minimum of one-year of instrument warranty to include on-site software upgrades, hardware repair, as a minimum annual instrument preventative maintenance service visits which includes all parts except for consumables listed in the specifications below, travel, and labor at no additional cost to the USEPA. The warranty period shall begin at the time of final acceptance of the instrument, once it has been demonstrated to meet all of the specifications provided herein. 19.The system shall be delivered within 6 months of the awarding of the contract, and installation and training shall be completed within 90 days after delivery to the USEPA/Office of Research and Development/National Exposure Research Laboratory/Environmental Methods and Measurements Division in RTP, NC. Upon installation, all non-conformances to the technical specifications shall be addressed and corrected at no additional cost to the USEPA. Within 21 days of award of the contract, the vendor shall provide the estimated shipping, delivery, and installation dates. The EPA has identified Thermo Electron North America, LLC as the only contractor able to meet the requirements of this procurement. Thermo Electron North America, LLC is the only contractor with an UPLC-HRMS that is capable of performing at minimum resolution of 200,000 for both parent ions and fragment ions with less than 1ppm mass accuracy and does not require specialized equipment (for example liquid nitrogen or argon cryogenic gas requirements for operation) or room modifications to operate. This procurement will be accomplished under FAR Part 12 and FAR Part 13 Procedures. Interested firms may identify their interest and capability to respond to the requirements. THIS NOTICE OF INTENT IS NOT A REQUEST FOR COMPETITIVE QUOTATIONS. Any firm that is capable of meeting EPA's requirement as set forth above may submit a response; which, if received within fifteen (15) calendar days of the date of this announcement, will be reviewed for consideration. A determination not to compete the described requirement based upon responses to this notice is solely within the discretion of the Government. Responses to this posting must be submitted via the FedConnect website at https://www.fedconnect.net through the message center for SOL-CI-17-00033. Mail, fax, phone and email submissions shall not be accepted. One or more of the items under this acquisition is subject to Free Trade Agreements. EPA anticipates that award will be made by June 30, 2017.
- Web Link
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(https://www.fbo.gov/spg/EPA/OAM/OH/SOL-CI-17-00033/listing.html)
- Record
- SN04496848-W 20170506/170504235907-dd7ce8e72791605c6153fc2ea62c4abd (fbodaily.com)
- Source
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