SOURCES SOUGHT
Q -- NCATS Pharmacologically Active Chemical Toolbox (NPACT) commercial powder reformatting
- Notice Date
- 5/8/2017
- Notice Type
- Sources Sought
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SS-2017-356
- Archive Date
- 5/30/2017
- Point of Contact
- Stacey M Polk,
- E-Mail Address
-
spolk@nida.nih.gov
(spolk@nida.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The National Center for Advancing Translational Sciences (NCATS) is a part of the National Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. DPI will include the molecules in the NCATS Pharmacologically Active Chemical Toolbox (NPACT) small molecule collection, which was initially solubilized and prepared in 2015. NPACT aims to broadly cover all biological mechanisms known in literature or patents and provides information access for NCATS investigators to accelerate their research. Purpose and Objectives: NCATS DPI Compound Management (CoMa) has been tasked with assembling the NPACT library. The purpose of this requirement is to solubilize ~44,000 compounds in DMSO to 10mM concentration and distribute them for HTS screening to the National Center for Advancing Translational Sciences (NCATS) Division of Preclinical Innovation (DPI) and allow CoMa to provide uninterrupted service to NCATS and concurrently assemble this library for HTS screening. Specific Requirements: 1.The Contractor shall solubilize each 1dram barcoded vial containing ~5mg powder (DPI will provide the vial barcode, exact weight of powder in each vial to 1 decimal point, and formula weight of each sample) to 10mM in 100% DMSO solvent. 2)The Contractor will visually verify that the powder is completely solubilized before distribution to the destination labware. 3)If the sample cannot be dissolved to 10mM, subsequent dilutions will be attempted at 5mM, 2.5mM, and 1.25mM before distribution to the destination labware. 4)The Contractor will distribute up to 900uL of solution to each of 2 Matrix barcoded tubes, cap each tube with a Sepraseal cap, and place them in separate barcoded Matrix racks. 5)The Contractor will distribute 20uL solution of each sample to a different well in a 384-well plate which will be thermally heat sealed. Anticipated Period of Performance/Delivery Date: Date of Award to within six months after receipt of government provided material Capability statement /information sought. Contractors that believe they possess the ability to provide the requirement should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. The response should directly and specifically state in the, capabilities statement, which project requirements you can supply. Contractors must also provide their Company Name, DUNS Number, Physical Address, Point of Contact, and Size and Type of Business (e.g., 8(a), HubZone, etc.) pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. The information submitted must be must be in an outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses (capability statements) sent in response to this Sources Sought Notice must be submitted electronically (via e-mail) to the Contract Specialist. Facsimile responses are NOT accepted. The response must be submitted to Stacey Polk, Contract Specialist at spolk@nida.nih.gov. The response must be received no later than the close date of this notice. "Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/HHS-NIH-NIDA-SSSA-SS-2017-356/listing.html)
- Place of Performance
- Address: National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland, 20850, United States
- Zip Code: 20850
- Zip Code: 20850
- Record
- SN04499917-W 20170510/170508234821-058af04c4a0288c346191ef69372d6fc (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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