Loren Data's SAM Daily™

FBO DAILY - FEDBIZOPPS ISSUE OF MAY 18, 2017 FBO #5655
DOCUMENT

66 -- Automated Behavioral and Physiological System - Attachment

Notice Date

5/16/2017
 

Notice Type

Attachment
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

US Department of Veterans Affairs;Veterans Health Administration;Service Area Office (SAO) East;323 North Shore Drive, Suite 500;Pittsburgh PA 15212-5319
 

ZIP Code

15212-5319
 

Solicitation Number

VA24017Q0132
 

Archive Date

7/15/2017
 

Point of Contact

Contracting Officer: Michael Haydo
 

Small Business Set-Aside

N/A
 

Description

This is a PRE-SOLICITATION NOTICE of a proposed requirement to award one (1) Integrated Small Animal Integrated Behavioral and Physiological Assessment System. Noldus Ethovision XT or equal. This action also requires shipping, and installation. System Components: # Description Est. Qty. Unit 1 Noldus Ethovision XT system platform bundle which includes items 2 - 18 (or equal) 1 EA 2 Morris Watermaze Part of Ethovision XT bundle (or equal) 1 EA 3 Open Field Part of Ethovision XT bundle (or equal) 1 EA 4 Elevated Plus Maze Part of Ethovision XT bundle (or equal) 1 EA 5 Zero Maze Part of Ethovision XT bundle (or equal) 1 EA 6 Novel Object Recognition Part of Ethovision XT bundle (or equal) 1 EA 7 Fear Conditioning Part of Ethovision XT bundle (or equal) 1 EA 8 Optogenetics Tool Kit Part of Ethovision XT bundle (or equal) 1 EA 9 Radial Arm Maze Part of Ethovision XT bundle (or equal) 1 EA 10 T-maze, Y-maze and Barnes Maze Part of Ethovision XT bundle (or equal) 1 EA 11 Porsolt forced Swim Test Part of Ethovision XT bundle (or equal) 1 EA 12 Social Interaction Part of Ethovision XT bundle (or equal) 1 EA 13 Conflict avoidance Part of Ethovision XT bundle (or equal) 1 EA 14 Sociability test Part of Ethovision XT bundle (or equal) 1 EA 15 Home cage Assessment Part of Ethovision XT bundle (or equal) 1 EA 16 Rotarod Part of Ethovision XT bundle (or equal) 1 EA 17 PhenoWheel Part of Ethovision XT bundle (or equal) 1 EA 18 Feeding/drinking assessments Part of Ethovision XT bundle (or equal) 1 EA 19 Media Recorder 4.0 (or equal) 1 EA 20 Noldus Observer XT 13.0 (or equal) 1 EA 21 CatWalk XT 10.1 (or equal) 1 EA 22 Erasmus Ladder (or equal) 1 EA 23 PhenoTyper 4.0 boxes (or equal) 1 EA 24 Small Rodent Treadmill w/ Shocker 1 EA Salient Characteristics Integrated Small Animal Integrated Behavioral and Physiological Assessment System The proposed system shall allow for a single animal to be analyzed for multiple, clinically-relevant parameters to generate a behavioral and physiological profile for each animal as a function of time, injury model, disease progression, or intervention. At a minimum the system shall: (1) TRACK a MINIMUM of 100 ANIMALS: Track up to 100 subjects simultaneously in Multiple Arenas with up to 16 subjects (i.e. mice) in a single arena. (2) INTEGRATE THE FOLLOWING APPLICATIONS: Automated tracking for multiple paradigms, using intuitive drawing tools to define your arena: Water Maze, Open Field, Plus Maze, T Maze, Zero Maze, Radial Arm Maze, Novel Object, Forced Swim, Fear Conditioning, Home Cage Assessment, CPP, Barnes Maze, Sociability, Social Interaction, and custom mazes/arenas. (3) NOSE-CENTER-TAIL BASE TRACKING: Crucial for Novel Object Recognition and Sociability experiments. (4) INTEGRATION WITH EXTERNAL HARDWARE: Trial & Hardware Control Module to communicate with external devices and systems (dispensers, wheels, lights, sounds, optogenetics, physiological recordings, ultrasound, and treadmill etc.). (5) TRACKING LIVE FROM DIGITAL VIDEO: Live tracking via direct input from a camera and tracking from pre-recorded digital video files (formats: MPEG1, MPEG2, and MPEG4) can be recorded first (and stored on HD, DVD or the network) for subsequent analysis. (6) TRACKING LIVE WHILE RECORDING DIGITAL VIDEO FILES: Network card to double as a digital video recorder to record digital video files DURING live tracking. (7) VIDEO INPUT, MULTIPLE INPUTS (TOP DOWN OR SIDE VIEW): Analog, GigE, and Firewire cameras with the ability to capture 4 cameras at once, equipment shall track one or multiple animals from multiple camera inputs simultaneously, in full resolution, eliminating the need for multiplexers and saving time. (8) DIGITAL VIDEO RESOLUTION: Media files of a resolution of 1400 x 1000 or higher is required. (9) TRACKING PARAMETERS: The number of parameters shall include at minimum: Trial duration, In zone, Distance to zone, Distance to zone border, Distance moved, Velocity, Heading, Turn angle, Angular velocity, Mobility, Proximity, Rotations, and Elongation. The statistics calculated for each parameter include mean, variance, standard deviation, standard error, maximum, minimum, sum, total, and number of samples (which ones apply depend on the parameter). (10) MANUAL CODING OPTION: Ability to manually code additional, user-specified behaviors while tracking. (11) TRACK EDITOR: Ability to find and correct errors in individual tracks or all tracks in a single trial. (12) ACTIVITY DETECTION: Quantifying movement and activity separate from tracking coordinates using pixel change frame by frame for activity/inactivity/freezing analysis in fear conditioning, and forced swim task. (13) ZONES OF INTEREST: Up to 10,000 zones defined for each individual arena, while multiple zones combined into cumulative zones. (14) HIDDEN ZONES: If rodents can be obscured (e.g. by a nesting box), then such areas can be defined as a hidden zone. Equipment shall keep track of how long the subject stays in that zone. (15) LIGHTING OPTIONS: Equipment must operate in both normal and infrared light (IR), from above and through backlighting. Using IR provides the user with the option to track multiple subjects in total darkness or in changing light conditions. (16) DETECTION METHODS: Equipment shall offer the following FOUR detection methods and settings, optimizing video tracking for more accurate results: Gray scaling Define all connecting pixels with a gray value above a certain threshold or below another threshold as a possible object. This method can be used when the entire background contains no gray scale values the same as the animal. Static Subtraction Looks at differences between pixels in a reference image and the new digitized image. With this method animals can be tracked in setups where the background contains pixels the same value as the animal. Dynamic Subtraction Looks at differences between pixels in a continuously updated reference image and the new digitized image, allowing for changes in the environment during tracking, within the same trial. Differencing With this method detection tracking in uneven illuminated areas becomes much more accurate, allowing for uneven lighting condition. It also improves tracking of multi-colored animals. (17) IMAGE FILTERING: Equipment shall offer two image filters that allow for adjustment of the digitized image of the animal detected during the tracking process to avoid accidental mix-up of the object with background noise and to improve body shape-related parameters. These image filters are: Erosion Filter Reduction of the geometrical area by removing pixels around the object s boundary. This function can be used to eliminate parts of the detected object that stick out, like tails and legs. Dilation Filter Increase of the geometrical area by adding pixels around the object s boundary. This function can be used to connect parts of the objects that were separated during object detection. (18) INTEGRATED VISUALIZATON OF TRACKS: The recorded tracks must be able to be superimposed on the simultaneously recorded digital video recording and played back in sync. (19) HEATMAP VISUALIZATION: Visual representation of animal distribution in real-time and in modalities appropriate for presentations and publications. (20) BATCH PROCESSING: Recorded digital video files shall be able to be processed in Batch Mode, which is typically much faster than in real time. (21) GROUP STATISTICS AND CHARTS: Results can be grouped and graphed even before export to MS Excel for further statistical analysis. 6. Additional equipment specifications: Each component listed below in the proposed system shall be fully integrated into the entire system to capture, process, analyze, and preset data in an integrated fashion: The CatWalk XT 10.1 (or equal) is a system for quantitative assessment of footfalls and motor performance in rodents. The tool assesses gait and locomotion as the specimen traverses a glass plate voluntarily (towards a goal box) while its footprints are captured. Driven by the EthoVision XT software, the CatWalk XT 10.1 visualizes the prints and calculates statistics related to print dimensions and the time and distance relationships between footfalls. The proposed system shall have validated research and experimental procedures for several neurological disorders and lesions including spinal cord injury and other nerve injuries, neuropathic pain, arthritis, stroke, Parkinson s, Cerebellar ataxia, traumatic brain injury (TBI), peripheral nerve damage. The ErasmusLadder (or equal) is a complete system for the assessment of motor performance and motor learning in animal specimens. The apparatus consists of a horizontal ladder between two goal boxes. The specimen traverses the ladder while the touch sensitive rungs allows the system to measure step time and length, missteps, back steps, and jumps, while cerebellar functioning is tested in a challenge which involves a barrier. The PhenoTyper 4.0 box (or equal) is an instrumented observation cage to measure and test the behavior of rodent specimens. The integrated system is equipped with a top unit, including LED units and a camera, and optionally with other sensor and stimuli devices such as sound generators, operant conditioners, lick-o-meters, feeding monitors, exercise wheels, and optogenetic stimulus devices (commutator in the ceiling). An external triggering module shall allow for the software package to interact with other equipment already on station in order to control the activation of telemetry systems such as the Indus Instruments MouseMonitor Telemetry system. The EthoVision XT (or equal) software shall allow the integration of key telemetry data (i.e. ECG, heart rate, activity, core temperature) with the initiation of physical exertion (i.e. treadmill, PhenoWheel), and thereby provide a means to measure exercise tolerance in small animal models of cardiovascular disease. Shipping FOB Destination and installation shall be included in the overall price. The Veteran s Health Administration Service Area Office - East estimates a posting date of solicitation VA240-17-Q-00132 on May 22, 2017 and distributed solely through the Federal Business Opportunities (FBO) Website (www.fedbizopps.gov). This notice does not constitute a Request for Proposal (RFP) and should not be construed to as a commitment of any kind by the Government to issue a formal solicitation or ultimately award a contract. Responses to this notice are not offers and cannot be accepted by the Government to form a binding contract. Any costs incurred by interested parties will NOT be reimbursed. It is the responsibility of any interested party to monitor this site for additional information pertaining to this notice. The agency is contemplating single award of a firm fixed price (FFP) contract to the contractor whose submission represents best value to the Government. The intention of this notice is to seek sources that could potentially provide these items under a Service Disabled Veteran Owned Small Business Set-aside, or a Veteran Owned Small Business Set-Aside. Firms with interest and capability to respond to this requirement should develop short (1 page or less) narrative capability statement including relevant information indicating and evidencing capability to successfully meet the aforementioned requirements. Responding to this not does not guarantee any opportunity for the contract, and is only used for VA planning purposes. Capability responses will be accepted until 10:00 AM (est) on May 22, 2017. The North American Industry Classification System code is 334510 electromedical and Electrotherapeutic Apparatus Manufacturing. Interested parties shall be registered in the System for Award Management at (www.sam.gov). Contracting Office Address: 323 North Shore Dr. Pittsburgh PA, 15212 United States Primary Point of Contact: Michael Haydo Contracting Officer Email: michael.haydo@va.gov Phone: 412-822-3158
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/notices/d1d18480fb56548ba25d5d4375299946)
 

Document(s)

Attachment
 

File Name: VA240-17-Q-0132 VA240-17-Q-0132.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3500199&FileName=VA240-17-Q-0132-000.docx)

Link: https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=3500199&FileName=VA240-17-Q-0132-000.docx

 

Note: If links are broken, refer to Point of Contact above or contact the FBO Help Desk at 877-472-3779.
 

Record

SN04511242-W 20170518/170516235336-d1d18480fb56548ba25d5d4375299946 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

---

| FSG Index  |  This Issue's Index  |  Today's FBO Daily Index Page |