SOURCES SOUGHT
66 -- TMS (transcranial magnetic stimulation)-MRI (magnetic resonance imaging) or compatible
- Notice Date
- 6/9/2017
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 6001 Executive Boulevard, Room 3165, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-2017-392
- Archive Date
- 7/8/2017
- Point of Contact
- Andrea McGee, Phone: 301480-2449
- E-Mail Address
-
amcgee@nida.nih.gov
(amcgee@nida.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- SOURCES SOUGHT NOTICE 1.Solicitation Number: HHS-NIH-NIDA-SSSA-SBSS-2017-392 2.Title: Scientific Equipment 3.NAICS Code: 334516 4.Description: TMS (transcranial magnetic stimulation)-MRI (magnetic resonance imaging) or compatible This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: 1.TMS is a non-invasive method used to study aspects of human brain physiology such as language, vision, motor systems, and changes on functional anatomy as a consequence of brain disorders. It can be used to excite or inhibit a specific brain area triggering the activation or suppression of the related brain function, allowing functional mapping of cortical regions. Despite its extended use in healthy and the drug-addicted population the underlying mechanism is still unknown. Magnetic resonance imaging (MRI) provides high-resolution scans of the human brain and other organs where image contrast is based principally on regional differences in proton relaxation times. The sensitivity of magnetic resonance to various aspects of tissue physical chemistry led to the development of a functional MRI (fMRI) technique that can probe tissue physiology and pathology beyond the scope of simple anatomical imaging. Therefore, the combination of TMS-fMRI offers unique opportunities to non-invasively evaluate the propagated neuronal activity induced by TMS, as it allows us to stimulate brain circuits while simultaneously monitoring changes in its activity and behavior. Such an approach can help to identify brain networks of functional relevance, and support causal brain behavior inferences across the entire brain. Therefore, this multimodal technique is novel approach to elucidating the underlying mechanisms effected by magnetic stimulation. 5.Purpose and Objectives: The purpose of this acquisition is to procure a TMS (transcranial magnetic stimulation)-MRI (magnetic resonance imaging) 4.Salient characteristics This is an advanced, high performance magnetic stimulator designed primarily for research purposes. It is a high-quality tool for researchers with a large choice of stimulating parameters and has stimulation rates up to 100 pps at high intensities and the possibility to combine waveforms and pulse modes. Features •3 waveforms: Biphasic, Biphasic Burst and Monophasic. •Selectable current direction. •Stimulation rates up to 100 pulses per second. •Easily connects to external equipment via programmable input/output triggers. •System operation control via a built-in computer, eliminating the need for an external computer to set up and control the timing of stimulus sequences. •Controllable from an external device. •Flexible protocol storage in built-in computer. •Effective burst function. The enhanced stimulation capabilities such as: •Dual pulses with up to 20 pulse pairs per second repetition rate •Advanced power pulse feature adding 40% additional stimulation power •Biphasic, Monophasic and Half sine Reduced RF Noise The Power line filter provides high image quality and allows equipment to be used in scanners from 1.5-4.00 Tesla. RF noise can greatly affect the signal-to-noise ratio. To effectively prevent RF noise being brought into the scanner room from the stimulator, a Power Line Filter mounted on the outside of the scanner wall, filters power and signal cables. The power line filters reduce 40MHz to 200MHz RF noise by 99.99%, which allows use in scanners in the 1.5T (RF 64MHz) to 4.0T (RF 170MHz) range. Balanced Leakage Current 1)Eliminates leakage currents through internal circuits. To reduce Leakage Current in the coil while it is not stimulating, the stimulators for TMS/fMRI are modified so that a reverse current is sent into the output connector with reverse "polarity" and proportional to the intensity. 2)Stimulator Recharge Delay Prevents unwanted noised generated when stimulator recharges until acquisition of images is completed. The noise generated when the stimulator recharges can interfere with image quality. The Charge Delay functionality in the TMS/fMRI solution from the stimulator can inhibit this noise. The charge delay can be adjusted from 0 ms to 12.000 ms. Increased Safety Smart sensors limit unsafe pulse configurations and temperature increases. Safety aspects are dealt with effectively. Due to the static magnetic field of the scanner, the MRi-B91 coil can only withstand standard biphasic pulses and for this reason the stimulators are automatically locked in biphasic pulse mode when the MRi-B91 is attached. Coil, Remote Control and Emergency Stop contain no ferromagnetic materials and two emergency stops can be connected - one for the patient/volunteer; one for scanner personnel MRi-B91 coil Designed for use in MRI scanners up to 4 Tesla. Only to be used with biphasic waveform and standard mode - not for use with power mode or any other waveforms. The coil is suitable for focused stimulation. Symmetrical placed inside the housing so the magnetic field on both sides is equal. The mere presence of the coil can create artifacts. In order to minimize eddy current effects, individually isolated copper litze wires are used in the MRi-B91 coil. To minimize coil vibrations, which also cause artifacts, the mechanical damping properties of the coil have been optimized. To ease installation in MR-compatible coil holders, the MRi-B91 comes with two holes at the center of the two windings. 1)System requirements/recommendations: •To get maximal performance of the coil, the stimulator should run software edition 7.1.0 or newer •To get maximal performance of the coil the hardware of the stimulator should be from 2012 or updated after 2012 •To reach optimal cooling performance the air flow must be minimum 5m3/h •To get the maximum number of stimuli available before coil warm-up, pauses between trains must be at least 8 seconds 2)Mechanical Properties •Weight of transducer head: 1.1 kg •Cable length 6 m •Dimensions of transducer head 175 x 142 x 30 mm 3)Coil Winding Data •Inner diameter 2 x ø35/ø52 •Outer diameter 2 x ø79/ø92 •Winding height 16mm •Number of windings 2 x (2x4) •Distance between centers 79 mm 4)Magnetic and Electrical Properties •Max initial dB/dt 24 kT/s. •Active pulse width with Filter box 280µs (Biphasic). 5)Performance incl. Filter Box Temperature warm-up at 100%: +30m°C/pulse Anticipated period of performance: 60 days ARO Capability statement /information sought. Contractors that believe they possess the ability to provide the requirement should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. The response should directly and specifically state in the, capabilities statement, which project requirements you can supply. Contractors must also provide their Company Name, DUNS Number, Physical Address, Point of Contact, and Size and Type of Business (e.g., 8(a), HubZone, etc.) pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses (capability statements) sent in response to this Small Business Sources Sought Notice must be submitted electronically (via e-mail) to the Contract Specialist. Facsimile responses are NOT accepted. The response must be submitted to Andrea McGee, Contract Specialist at e-mail address amcgee@mail.nih.gov The response must be received on or before June 23, 2017 at 12:00PM, eastern time. "Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SBSS-2017-392/listing.html)
- Place of Performance
- Address: 251 Bayview Blvd, Baltimore, Maryland, 21224, United States
- Zip Code: 21224
- Zip Code: 21224
- Record
- SN04539794-W 20170611/170609234732-e8149c661242c704fa0199735466b3a6 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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