SOURCES SOUGHT
66 -- Microscopy System for Deep Brain Imaging
- Notice Date
- 7/10/2017
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-17-536
- Archive Date
- 8/4/2017
- Point of Contact
- Sneha V Patel, Phone: 3014802443
- E-Mail Address
-
sneha.patel@nih.gov
(sneha.patel@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Federal Business Opportunities (FBO) SOURCES SOUGHT NOTICE Solicitation Number: HHS-NIH-NIDA-SSSA-17-536 Title: Mini Microscope System Classification Code: 6640 NAICS Code: 334516 Description: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: Opioid analgesics are highly addictive and widely prescribed for acute and chronic pain. This project seeks to develop alternative therapies for opioid prescription by determining causal neural activity which underlies opioid analgesia and relief from stress and pain. The project involves examining causal determinants of addiction including whole-cell patch clamp physiology, cellular activity, and behavior and aims to determine casual links between these levels in understanding stress-driven opioid seeking. In vivo imaging is particularly informative by providing a causal link to behavior in which the progression of the disease can be observed in cellular activity real-time. Understanding which brain regions contribute to the rewarding properties of opioids and the distinct areas which cause analgesia exclusively in the absence of reward is critical in developing effective, non-addictive therapies. Furthermore, the project aims to develop both brain stimulation therapies and pharmacological therapies for opioid addiction and stress reactivity using these activity patterns and maps. Understanding the specific cause activity changes across an extended time period will provide an unprecedented access to neural activity changes across the progression of opioid addiction. Purpose and Objectives: The purpose is to provide a real-time neuronal measure that links behavioral outcomes to stress and seeking for opioid drugs to electrophysiological changes within deep brain structures and to observe this activity over the lifespan of the animal. The main objective is to observe disease progression (i.e., addiction) over the course of opioid administration in response to stressful stimuli, including pain. The outcomes obtained from these studies will inform the lab about how activity changes in response to pain and stress and how these factors contribute to continued voluntary seeking of opioid-mediated analgesia or relief, therefore providing a cellular target for brain stimulation therapy which can be used in place of opioid analgesics Project requirements: One (1) Fluorescence Microscopy System for Deep Brain Imaging • Fluroscence Microscope Driver o Ethernet cable 2m, M8 cable 1m, USB memory stick with software, power cord • Connectorized Single LED, Blue • Fluroscence Microscope Holder • Clamp for Fluroscence Microscope Holder • Mono Fiberoptic Patch cord o 200 µm core o 230 µm cladding o 1 m • Assisted Optical & Electrical rotary joint, pigtailed • FC/FC Mating Adapter (2) • Mono Fiberoptic Patch cord o 200 µm core o 230 µm cladding o.8m • Mono Fiberoptic Patch cords (3) o 200 µm core o 230 µm cladding o.8m • Snap-In Fluroscence Microscope Body o Ultralight fiberglass jacket • Dummy Snap-In Microscope Body • Snap-In Imaging Cannula (10) o Depth Range 2.87mm-5.96mm • Fluoroscence Micropscope Snaping Tool Anticipated period of performance: 40 days from date of award. Capability statement: Contractors that believe they possess the ability to provide the required services should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. The capability statement should include 1) the total number of employees, 2) documentation of ability to provide the required support, 3) any contractor GSA Schedule contracts by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Contractors must also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted to Sneha Patel, Contract Specialist, via email at sneha.patel@nih.gov before the closing date and time of this announcement. All responses must be received by the specified due date and time in order to be considered. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
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- Record
- SN04573278-W 20170712/170710235806-9acdad422cbb95247a4376f610299a0d (fbodaily.com)
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