SOURCES SOUGHT
66 -- Tissue Clearing System - Sources Sought
- Notice Date
- 7/18/2017
- Notice Type
- Sources Sought
- NAICS
- 423490
— Other Professional Equipment and Supplies Merchant Wholesalers
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support/Simplified Acquisitions, 6001 Executive Boulevard, Room 3165, Bethesda, Maryland, 20892, United States
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SS-2017-549
- Archive Date
- 8/12/2017
- Point of Contact
- Catherine Caldwell, Phone: 3014802467, Nancy Lamon-Kritikos, Phone: 3014433203
- E-Mail Address
-
catherine.caldwell@nih.gov, Nancy.lamon-kritikos@nih.gov
(catherine.caldwell@nih.gov, Nancy.lamon-kritikos@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Sources Sought full Description This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The Wang lab seeks to understand how genetic and experiential factors impact the developmental trajectory and functional architecture of brain circuits critically involved in psychiatric disorders in order to develop improved treatment and management for these diseases. Among the core deficits associated with serious psychiatric disability, the impairment of executive function, affecting the planning, initiation and regulation of goal-directed behaviors, has been increasingly highlighted as of central importance. Normal executive function in goal-directed behavior depends on the frontal lobe, and functional brain imaging studies have revealed altered activities in this brain region in patients suffering from schizophrenia, depression and drug addiction. However, much less is known about the cellular and molecular mechanisms by which genetic and environmental factors perturb the development and function of frontal cortical circuits. Lack of such knowledge has hampered the identification of key cellular targets and molecular pathways for therapeutic interventions. The current focus of Wang Lab is to elucidate the basic cellular and molecular mechanisms underlying experience-dependent regulation of frontal cortical circuits in model organisms. Many of the experiments in the Wang lab involve imaging of mice brains. Tissue clearing is a novel way of imaging the whole brain by making it transparent. Fluorescent or antibody labeled proteins can be visualized in the transparent brains.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-2/HHS-NIH-NIDA-SSSA-SS-2017-549/listing.html)
- Record
- SN04585096-W 20170720/170719000108-b66d74757397ba66d125a17622d7041f (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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