SOLICITATION NOTICE
99 -- PNA monomers
- Notice Date
- 8/3/2017
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 325414
— Biological Product (except Diagnostic) Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Child Health and Human Development, Contracts Management Branch, 6710B Rockledge Dr., Suite 1124, MSC7000, Bethesda, Maryland, 20892-7510, United States
- ZIP Code
- 20892-7510
- Solicitation Number
- NIH-NIDDK-17-219
- Archive Date
- 8/29/2017
- Point of Contact
- Amber Harris, Phone: 3014028778
- E-Mail Address
-
amber.harris@nih.gov
(amber.harris@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NIH-NIDDK-17-219 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-95. The North American Industry Classification (NAICS) Code is 325414 and the business size standard is 1,25.0. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intend to procure on a sole source basis with PolyOrg, Inc. of 10 Powers Street, Leominster, MA 01453 for the purchase of PNA monomers. The National Institute of Digestive, Diabetes & Kidney Diseases's (NIDDK) The Synthetic Bioactive Molecules Section of the Laboratory of Bioorganic Chemistry is involved in the discovery and development of new molecules with medicinal value or for applications to diagnostics. Some of these molecules have the potential to become therapeutics or to be used as important components in diagnostic applications that signal the presence of disease. Applications in either area are of great benefit to human health and thus to NIDDK's mission. Research conducted in the Laboratory of Bioorganic Chemistry involves synthesis of biologically active molecules called peptide nucleic acids (PNAs). This purchase requisition is urgently needed to obtain starting materials needed to make and study PNAs. Each PNA must be able to recognize and bind its DNA or RNA target nucleic acid sequence, and without this starting material we cannot continue our research on the properties of PNA. The starting material needed is specific to the NIDDK's needs for the study of PNA binding to nucleic acids, and it must have the correct chemical composition. The NIDDK also requires reasonable quantities. Therefore, the material must meet the following specs: 1. 20 to 30 g of protected Peptide Nucleic Acid (PNA) monomers with the nucleobase that has a protecting groups on the exocyclic amine of the nucleobase as indicated in the order. 2. Each material provided with characterization data (NMR and HPLC) PolyOrg, Inc. will provide all the specific materials, including the cyclopentane-modified PNAs, with the correct stereochemistry and protecting groups. In the light of the NIDDK's ongoing studies, consistency and continuity of research goals requires the utilization of PolyOrg, Inc.'s deliverables. The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under authority of the 41 U.S.C. 253(c) (1), FAR 6.302. Only one responsible source and no other supplies or services will satisfy agency requirements. The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation - Commercial Items; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of furnishing the government with the services specified in this synopsis should submit a copy of their quotation to the below address or via email to amber.harris@nih.gov. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all of the foregoing requirements. Quotations will be due on or before August 14, 2017 by 10 am, EST. via email or postal mail. The quotation must reference "Solicitation number" NIH-NIDDK-17-219. Quotations sent by postal mail or other mailing services must be submitted to the following address: Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Drive, Room 1159A, Bethesda, MD 20817. Attention: Amber Harris, by the date and time mentioned above. Any questions must be sent via email to amber.harris@nih.gov and must include solicitation#NIH-NIDDK-17-219 in the subject line of email. Faxed copies/responses will not be accepted. PLEASE NOTE: In order to receive an award, contractor must be registered for "All Awards" and have a valid certification in the System for Award Management (SAM) database at http://www.sam.gov.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NICHD/NIH-NIDDK-17-219/listing.html)
- Place of Performance
- Address: BETHESDA, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04610322-W 20170805/170803231717-eb0d41bf0ab0237ac45cafb1e6fc0550 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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