SOURCES SOUGHT
66 -- Upgrades: Existing Spinning Disk System
- Notice Date
- 8/5/2017
- Notice Type
- Sources Sought
- NAICS
- 333314
— Optical Instrument and Lens Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Nat'l Institute of Diabetes, Digestive, & Kidney Diseases, 2 Democracy Plaza, Suite 700W, 6707 Democracy Blvd., MSC 5455, Bethesda, Maryland, 20892-5455
- ZIP Code
- 20892-5455
- Solicitation Number
- NICHD-17-194
- Archive Date
- 8/29/2017
- Point of Contact
- Verne Griffin,
- E-Mail Address
-
verne.griffin@nih.gov
(verne.griffin@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This Small Business Sources Sought Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation or commitment by the Government. This notice is intended strictly for Market Research. The National Institutes of Health (NIH) Eunice Kennedy Shriver, National Institute of Child Health and Human Development is conducting a market survey to determine the availability and technical capability of qualified small business, veteran-owned small business, service-disabled veteran-owned small business or HUBZone small businesses capable of providing Upgrades: Existing Spinning Disk System: Dual Camera, Piezo Z, Software and Workstation. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Intramural Research Program (IRP) conducts biomedical research and training related to diabetes mellitus; endocrine, bone, and metabolic diseases; digestive diseases, including liver diseases and nutritional disorders; and kidney, urologic, and hematologic diseases. Intramural research is conducted in the Institute's laboratories and clinical facilities in Bethesda, Maryland and in Phoenix, Arizona. There are currently 19 Laboratories and Branches (i.e. 19 departments with different focus areas) in the NIDDK IRP. Most if not all these areas of research, either occasionally or on an ongoing basis, require advanced fluorescence microscopy, including confocal microscopy, as the basis of a quantitative assay or to qualitatively complement other assays. The Spinning Disk Confocal Microscope (SDC) was originally purchased to satisfy such a need. Spinning disk confocal microscopy has been, and remains the best technology to image live cultured cells, labeled with fluorescent markers, over time. The LERB SDC thus provides a useful technology resource for other NIDDK departments outside LERB. Although the LERB SDC is useful to some in its current state, it requires upgrades to keep pace with technology and users' wishes for experiments. It is not nearly as sensitive nor as fast as what is currently available on the market, and several NIDDK researchers have not been able to pursue experiments that would greatly advance their studies. Because this SDC has hardware-based autofocus and the capability to turn lasers on/off within a few microseconds, whereas other SDCs in NIDDK do not have these features, it is the most cost-effective to upgrade this SDC to current technology, to answer researchers' experimental requirements. All tasks need to be compatible with existing hardware and functionality of this Spinning Disk Confocal Microscope. Replacement of the existing CCD camera (NIH keeps the old camera) with dual 3rd-generation CMOS cameras: Low light sensitivity and background noise reduction at least as good as the Hamamatsu Flash 4.0 v3. Pixel size when using a 100x lens should be 50-80 nm in the sample space. Software supports simultaneous or sequential imaging with the two cameras. Images from the two cameras can be aligned in a few minutes by trained NIH staff after changing the dichroic between the two cameras. Timing of camera acquisition is synchronized with laser on/off on a sub-millisecond time scale. Addition of piezo stage insert to enable much faster movements in between image acquisitions during z-stacks, with sub-msec synchronization with lasers and cameras. The intended procurement will be classified under North American Industrial Classification (NAICS) code 333314 with a size standard of 500. All respondents are requested to identify their firm's size and type of business. Interested firms responding to this market survey must provide (a) capability statement demonstrating their experience, skills and capability to fulfill the Government's requirements for the above. The capability statement shall be in sufficient enough detail, but not to exceed 15 pages, so that the Government can determine the experience and capability of your firm to provide the requirements above. Your capability statement, not to exceed 15 pages, should include references. Capability statement must be received at the email address identified in this synopsis by 10:00 A.M. local time on August 14, 2017. Any questions regarding this announcement must be sent via email to verne.griffin@.nih.gov and must include solicitation NICHD17-194 in the subject line of email. This synopsis is for information and planning purposes and is not to be construed as a commitment by the Government, nor will the Government pay for information solicited. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provided feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate response to a solicitation. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provided feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate response to a solicitation. Confidentiality - No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)." PLEASE NOTE: In order to receive an award, contractor must be registered and have valid certification in the System for Award Management (SAM) http://www.sam.gov
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDDKD/NICHD-17-194/listing.html)
- Record
- SN04614779-W 20170807/170805230213-01a0f1f027489146b99c66bd2cb4f212 (fbodaily.com)
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