SOLICITATION NOTICE
Q -- Urine Creatinine Testing for The National Cancer Institute’s (NCI) Metals, Micronutrients, and Gallbladder Cancer Study
- Notice Date
- 8/8/2017
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- N02CP72607-24-01
- Archive Date
- 9/1/2017
- Point of Contact
- Kimesha Leake, Phone: 2402765669, Jolomi Omatete, Phone: 2402766561
- E-Mail Address
-
kimesha.leake@nih.gov, jolomi.omatete@nih.gov
(kimesha.leake@nih.gov, jolomi.omatete@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E134, Bethesda, MD 20892, UNITED STATES. Non-USPS mail such as Fedex, UPS and other private carriers please use Rockville, MD 20850. The National Cancer Institute (NCI), Division of Cancer Epidemiology and Genetics (DCEG), would like to issue a contract to evaluate the association of metals and micronutrients with 1) GBC compared to gallstones and 2) gallstones compared to population-based controls. This is a combined synopsis/solicitation for commercial items, prepared in accordance with format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation: No. N02CP72607-24-01 includes all applicable provisions and clauses in effect through FAR FAC 2005-95 (January 2017) simplified procedures for commercial items. The North American Industry Classification System code is 541380 and the business size standard is $15.0 million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price contract. I. Description of Requirement BACKGROUND INFORMATION ON THE NCI STUDY: The Division of Cancer Epidemiology and Genetics (DCEG) is a research program of the National Cancer Institute (NCI), one of the National Institutes of Health (NIH). The Division is the world's most comprehensive cancer epidemiology research group. Its renowned epidemiologists, geneticists, and biostatisticians conduct population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention. The Division's research informs public health policy in the United States and around the world. DCEG carries out its research program with a cadre of in-house researchers and trainees. DCEG investigators conduct research on most cancer organ sites among diverse populations in the United States and around the world. They utilize a full range of research approaches to study risk factors ranging from workplace exposures to lifestyle choices. A number of metals, such as arsenic, cadmium, and chromium, have been associated with increased risk of many cancers. Micronutrients, which are elements required for normal growth and functioning in trace amounts and include both metals, like calcium, and non-metals, like selenium, have been associated with decreased cancer risk, however various studies yield contradictory results. The role of micronutrients seems to depend on the tissue type and concentration and timing of exposure. Exposure to metals and micronutrients is a combination of nutrition, environmental exposure, and occupational exposure. Many metals (e.g., lead, vanadium, chromium, cobalt, molybdenum, arsenic, manganese, calcium) are primarily excreted in urine. Thus, urine can serve as a valid measurement of body burden and exposure toxicity when biological specimens such as whole blood are not readily available. Few studies have evaluated the role of metals in gallbladder carcinogenesis. A small case-control Northern Chile has the highest levels of heavy metal (e.g., arsenic, cadmium, chromium) contamination in Chile, particularly with regard to copper and arsenic, and yet this region has the lowest risk of GBC nationwide. To clarify the role of metals and the possible interaction of heavy metals and micronutrients in biliary tract cancers, it is necessary to conduct larger studies in populations with wide variation in exposure. In addition, most studies have evaluated metals independently, not jointly, but co-exposure to metals and micronutrients can have synergistic or antagonistic effects on human health. The National Institute on Minority Health and Disparities (NIMHD) recently developed a "metallome" panel to allow simultaneous evaluation of metals and essential elements involved in human health using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). ICP-MS measures the presence of elements at the atomic level. Thus, elements are separated based on atomic mass. This metallome panel has the capability to measure metal measurements to the part per trillion (ppt) level in small sample sizes. The NCI proposes to apply this panel to serum and urine samples from the Shanghai Biliary Tract Cancer Case-Control Study. CONTRACTOR RESPONSIBILITIES: Urine creatinine testing on urine samples and data file with test results. NCI RESPONSIBILITIES: NCI will transfer the specimens to the contractor within the same month that the purchase order is awarded. Remaining samples should be returned to the NCI, the NCI technical point of contact will be responsible for coordination. Shipment fees will be covered by NCI. The NCI technical point of contact/COR will be in direct contact with the contractor as to the progress of the testing. Monthly follow-up will occur. Results are expected to be delivered a month prior to the end of the period of performance. If any issues arise they will be addressed in a timely manner during the monthly follow-up. DELIVERABLES Encrypted data file showing urine creatinine test results from 659 samples. PERIOD OF PERFORMANCE One year from date of award. QUESTIONS ARE DUE: August 14, 2017 The purchase order will be awarded to the Lowest Price Technically Acceptable (LPTA). The award will be made on the basis of the lowest evaluated price of quotations meeting or exceeding the acceptability standards for the requirements/technical specifications stated above. The technical evaluation will be a determination based on information furnished by the vendor. The Government is not responsible for locating or securing any information which is not identified in the quote. The Government reserves the right to make an award without discussions. PROVISIONS AND CLAUSES: The following FAR provisions and clauses apply to this acquisition: 52.212-1 Instruction to Offerors Commercial Items (October 2016) FAR 52.212-3, Offeror Representations and Certifications - Commercial Items (October 2016) - with Addenda [Representation By Corporations Regarding an Unpaid Delinquent tax Liability or a Felony Conviction Under Any Federal Law and FAR 52.204-6, Unique Entity Identifier (October 2016)] FAR 52.212-4, Contract Terms and Conditions - Commercial Items (May 2015) - With Addenda FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items (November 2016) The Contractor shall comply with the FAR clauses in this paragraph (b) that the Contracting Officer has indicated as being incorporated in this contract by reference to implement provisions of law or Executive orders applicable to acquisitions of commercial items: FAR 52.219-4, Notice of Price Evaluation Preference for HUBZone Small Business Concerns (OCT 2014) FAR 52.219-28, Post Award Small Business Program Representation (Jul 2013) FAR 52.222-3, Convict Labor (June 2003) FAR 52.222-21, Prohibition of Segregated Facilities (Apr 2015) FAR 52.222-26, Equal Opportunity (Sept 2016) FAR 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving (AUG 2011) FAR 52.225-13, Restrictions on Certain Foreign Purchases (June 2008) FAR 52.232-33, Payment by Electronic Funds Transfer-System for Award Management (Jul 2013) Full text copies of the representations and certifications for other cited provisions and clauses may be obtained on line at the NCI website at http://ncioa.cancer.gov/oa-internet/reference.jsp or from Kimesha Leake, Contracting Specialist at Kimesha.leake@nih.gov OFFERORS: Offers must be submitted with a completed 52.212-3 Offeror Representations and Certifications-Commercial Items-with DUNS Number Addendum, signed by an authorized representative of the offeror OR provide a copy of the valid SAM registration through www.sam.gov. Quotations must be received in the NCI-OA contracting office by 5:00 p.m. EST on August 17, 2017. Please refer to solicitation number N02CP72607-24-01 on all correspondence. Faxed quotations will NOT be accepted. Quotations may be submitted via email to Kimesha Leake, Contract Specialist at Kimesha.leake@nih.gov All questions shall be in writing and may be addressed to the aforementioned individual noted above. In order to receive an award, contractors must be registered and have valid certification in the System for Award Management through sam.gov.
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