SOLICITATION NOTICE
B -- Statistical and Programming Applications
- Notice Date
- 8/9/2017
- Notice Type
- Presolicitation
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Rockville, Maryland, 20852, United States
- ZIP Code
- 20852
- Solicitation Number
- N02RC72643-24
- Archive Date
- 9/2/2017
- Point of Contact
- Kimesha Leake, Phone: 2402765669, Jolomi Omatete, Phone: 2402766561
- E-Mail Address
-
kimesha.leake@nih.gov, jolomi.omatete@nih.gov
(kimesha.leake@nih.gov, jolomi.omatete@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E134, Bethesda, MD 20892, UNITED STATES Description The National Cancer Institute (NCI), Center for Cancer Research (CCR), Radiation Biology Branch (RBB) plans to procure on a sole source basis projects for statistical, comparative, radiation and mutation analysis from Genepria Consulting, 10015 Old Columbia Road, suite B215, Columbia, MD 21046-3239. This acquisition will be processed in accordance with the simplified acquisition procedures as authorized by FAR Part 13.106-1 (b) (1) and is exempt from the requirements of FAR part 6. The North American Industry Classification System Code is 541690 and the business size standard is $15.0 million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price, Indefinite Delivery, Indefinite Quantity type contract with a five year period of performance. It has been determined there are no opportunities to acquire green products or services for this procurement. The Radiation Biology Branch research activities are focused on pre-clinical basic science research aimed at identifying and incorporating novel approaches to cancer treatment, evaluation, and prevention. A variety of approaches are evaluated at the molecular, biochemical, cellular, and physiological levels including the impact of the tumor microenvironment and metabolic mutations to improve cancer treatment. Intentional or accidental exposure of humans to ionizing radiation or a course of definitive radiation therapy can lead to cancer induction or second malignancies. Research studies are directed to identify interventions to delay or prevent radiation-induced cancer after the exposure has occurred. Emphasis is placed on gaining a better understanding of the mechanisms of cell killing and protection and the activation/inhibition of complex signaling pathways mediated by oxidative stress, including ionizing radiation, reactive oxygen species (ROS), and reactive nitrogen species (RNS). The RBB plans to conduct multiple projects requiring both intensive statistical and programming applications. The Contractor shall study the effects of the antibiotics on the gut microflora of mice after whole body radiation exposure. The composition of gut microflora is known to be associated with certain diseases. The effects of wide range antibiotics with and without radiation treatment will be examined. Depending on the outcome of antibiotics, the RBB wishes to examine the changes in the urine metabolites by radiation exposure. A comparison of the gut microflora of cecum to that of pellets is planned to explore the possibility of non-invasive studies to reduce the number of animals. GenEpria Consulting, Inc. specializes in statistical analysis of large scale microarray data from a variety of platforms including gene, protein and microRNA expressions, large scale Metabolomics data and gut microflora 16S rRNA sequence data. GenEpria has successfully completed a previous study with RBB on radiation induced metabolite changes. GenEpria data analysis is unique because it takes the raw data from instruments and combines it into a coherent unit. GenEpria Consulting, Inc uses a high level data analysis (in particular time analysis), which allows the NCI to understand the underlying biological principles behind the results. The experiments the NCI will be doing the upcoming year will be done using these same instruments and require the same high level data analysis to make sense of the results. These are unique methods which we require in order to be consistent with the NCI's previously published work. This notice is not a request for competitive quotation. However, if any interested party, especially small businesses, believes it can meet the above requirement, it may submit a capability statement, proposal, or quotation, which shall be considered by the agency. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 5:00 PM EST, on August 18, 2017. All responses and questions can be emailed to Kimesha Leake, Contract Specialist via electronic mail at kimesha.leake@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must be registered and have valid certification in the System for Award Management (SAM) through sam.gov. Reference: N02RC72643-24 on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/N02RC72643-24/listing.html)
- Record
- SN04620202-W 20170811/170809232140-192bf63ec4b5938d0d58f2c93fa3eb33 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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