SOURCES SOUGHT
A -- Biomarker Study - RFI Instructions
- Notice Date
- 8/9/2017
- Notice Type
- Sources Sought
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of the Army, U.S. Army Medical Research Acquisition Activity, U.S. Army Medical Research Acquisition Activity, Attn: MCMR-AAA, 820 Chandler Street, Frederick, MD 21702-5014, Maryland, 21702-5014, United States
- ZIP Code
- 21702-5014
- Solicitation Number
- W81XWH17T0394
- Archive Date
- 9/8/2017
- Point of Contact
- Michael E Baughman, Phone: 3016192315
- E-Mail Address
-
michael.e.baughman.civ@mail.mil
(michael.e.baughman.civ@mail.mil)
- Small Business Set-Aside
- N/A
- Description
- Interested parties are asked to respond to the RFI and submit a capabilities statement that supports the focus of the RFI. Please review the place of performance requirements. Please submit written responses via email in Microsoft 2000 or 2007 format. All responses should be complete: in 12-point font; and not to exceed 5 pages total, including graphics, tables, and appendices. Provide a report of 22 confounding issues for each participant, showing the ID numbers of the PTSD cases and controls for the entire set of persons participating the study (350 total). Twenty-two confounding issues have been listed to date. Therefore, 22 individual sets of information will need to be determined from each of the 350 persons. This information is critical to be able to determine if the panels of biomarkers USACEHR has selected continue to identify PTSD if the individual are taking specific medicines, if they are being treated for depression or other co-morbidities, in the presence of alcoholism, etc. Additionally, USACEHR is asking whether some of the confounding factors (such as inflammatory markers) to separate subgroups of individuals. Such stratification into subtypes of PTSD will enable us to obtain a better success rate for the identification of persons with PTSD and have potential to provide a ‘personalized’ approach for therapeutic strategies. For the past 5 years, the consortium for Systems Biology of PTSD, has collaborated to carry out studies to determine a panel of measurements which will objectively identify PTSD. This report is urgently needed in order to test the current panels of molecular indicators. It will involve going through each file of the 350 persons in these various cohorts to determine which of the 22 overarching confounders is/is not present. The records which will be searched include notes from the oral psychiatric interview, each of the self-report tests addressing depression (Beck Depression Index), sleep quality (Pittsburgh sleep quality index), general symptoms (Symptoms checklist -90) and some 6 other detailed information report tools which form a basis of the analysis.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/USA/USAMRAA/DAMD17/W81XWH17T0394/listing.html)
- Place of Performance
- Address: Fort Detrick, Maryland, 21702, United States
- Zip Code: 21702
- Zip Code: 21702
- Record
- SN04621293-W 20170811/170809233222-7b0f091ccf19e828abe2052e6e3d1b29 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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