SOURCES SOUGHT
R -- Circadian Rhythm Tracking and Data Analysis
- Notice Date
- 8/16/2017
- Notice Type
- Sources Sought
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-2017-735
- Archive Date
- 9/4/2017
- Point of Contact
- Zenab A. Chowdhry, Phone: 3018276909, Nancy Lamon-Kritikos,
- E-Mail Address
-
zenab.chowdhry@nih.gov, nancy.lamon-kritikos@nih.gov
(zenab.chowdhry@nih.gov, nancy.lamon-kritikos@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- SOURCES SOUGHT NOTICE 1. Solicitation Number: HHS-NIH-NIDA-SSSA-SBSS-2017-735 2. Title: Circadian Rhythm Tracking and Data Analysis 3. NAICS Code: 541990 - All Other Professional, Scientific, and Technical Services Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, MD 20892. Introduction: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. North American Industry Classification System (NAICS) CODE: 541990 - All Other Professional, Scientific, and Technical Services Background Information: The mission of the National Institute of Mental Health (NIMH) is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure. For the Institute to continue fulfilling this vital public health mission, it must foster innovative thinking and ensure that a full array of novel scientific perspectives are used to further discovery in the evolving science of brain, behavior, and experience. In this way, breakthroughs in science can become breakthroughs for all people with mental illnesses. Purpose and Objectives for the Acquisition: The purpose of this acquisition is to procure thirty (30) animal lines as double or triple mutant lines to record circadian rhythmic data retrieved from animal specimens based on their behaviors when exposed to both light and dark environments. These services are needed to directly replicate certain aspects of our existing research. We are currently unable to perform the services being requested due to the lack of laboratory and facility space in addition to constraints on the number of animals and the housing of these specimens would require to fulfill specific aspects in support of our research. The Section on Light and Circadian Rhythms' aim is to understand the development and role of atypical mammalian photoreceptors, melanosin-containing retinal ganglion cells, in non-image forming (NIF) visual functions. These functions include circadian photoentrainment, pupillary light reflex, sleep, and direct light effects on behavior. We will also explore the effects of light on learning, memory, and mood and the mechanism by which light activates the melanopsin-containing cells. The main common tool used in all these studies is genetically mutated animal lines. Contractor Requirements (Scope of Work): General Requirements: Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to perform the specific requirements detailed below. Specific Requirements: The Contractor shall: 1. Provide the husbandry and breeding service for 30 double or triple mutant animal lines. 2. Conduct genotyping for 30 double or triple mutant animal lines. The cost of PCR reagents will be included in this service order. 3. Precisely control and manage special lighting conditions as directed by the NIH. 4. Collect mouse wheel-running and body temperature data from 30 mutant lines under each special lighting condition designed for different circadian experiment. 5. Conduct multiple behavioral tests using 30 mutant animal lines under special lighting conditions as directed by the NIH. 6. Collect actogram data sets and animal specimens from each support task performed for further analysis. 7. Conduct routine immunohistochemistry, in situ hybridization and sequencing procedures on the animal specimens collected from these support task performed. The contractor shall provide for all reagents (for example antibodies, fluorescent probes, et al.) associated with this requirement. GOVERNMENT RESPONSIBILITIES The Government will provide: 1. Lighting condition information for circadian tracking tasks. 2. Data collection software and templates for documenting task results. DELIVERY OR DELIVERABLES Delivery All data shall be returned to Dr. Samer Hattar on an external hard drive. The data files shall be in the following format: 1. The genotyping data will be delivered in Excel file format. 2. The lighting condition, wheel-running and body temperature data, and other behavioral tests data will be delivered in the format of each software used for data collection. 3. The data from immunohistochemistry, in situ hybridization and sequencing experiments will be delivered in Excel file and image file format. OTHER CONSIDERATIONS Travel: Travel is not required or authorized. Data Rights: The National Institute on Mental Health shall have unlimited rights to and ownership of all deliverables provided under this order. The definition of "unlimited rights" is contained in Federal Acquisition Regulation (FAR) 27.401, "Definitions". FAR clause 52.227-14, "Rights in Data-General," is hereby incorporated by reference and made a part of this contract/order. Anticipated period of performance: 09/30/2017 - 09/29/2018 This is an anticipated firm fixed price purchase order. Capability Statement: Contractors that believe they possess the ability to provide the required services should submit documentation of their ability to meet the project requirements to the Contract Specialist. Contractors should also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Small Business Sources Sought Notice must be submitted electronically (via email) to Zenab Chowdhry, Contract Specialist, at zenab.chowdhry@nih.gov in MS Word format within five (5) calendar days of the date of this announcement. All responses must be received by the specified due date and time in order to be considered. Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price contract. Contracting Office Address: 9000 Rockville Pike Building 31, Room 1B59 Bethesda, Maryland 20892 United States
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