SOURCES SOUGHT
65 -- Telemetry Scientific Device
- Notice Date
- 6/14/2018
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Clinical Center/Office of Purchasing & Contracts, 6707 Democracy Blvd, Suite 106, MSC 5480, Bethesda, Maryland, 20892-5480
- ZIP Code
- 20892-5480
- Solicitation Number
- 18-012319
- Archive Date
- 6/26/2018
- Point of Contact
- Priscilla S. Abalos, Phone: 3015943879
- E-Mail Address
-
priscilla.abalos@nih.gov
(priscilla.abalos@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Solicitation # HHSN-NIH-CCOPC-SBSS-18-012319 This is a Small business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources:(2) whether there are small businesses, HUBZONE small businesses, service disabled veteran-owned small businesses or (8a) small businesses, veteran- owned small business, woman-owned small businesses or small disadvantaged businesses veteran owned small businesses; woman owned businesses, or small disadvantaged businesses and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your response to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable code should not submit a response to this notice. Background Information The Critical Care Medicine Department (CCMD) was established in November 1977 to provide medical care for critically ill patients throughout the Clinical Center who have potentially reversible medical problems. Critical care medicine may be defined as the observation, diagnosis, treatment, and rehabilitation of patients with overt or potential failure of vital functions. The Department is currently composed of the following sections: • Clinical Medical Services • Critical Care Therapy and Respiratory Care • Research Section • AIDS Section • Administrative Services CCMD Mission To provide high quality and cost effective clinical service that meets the needs of CC patients and NIH Institutes, to facilitate the research goals of NIH Institutes and investigators, and to conduct high quality research and training in Critical Care Medicine. CCMD Research Section The Critical Care Medicine Department conducts active research programs in bedside clinical investigation, research in animal models, and molecular biology. Full-time research activities commence at the beginning of the second year of the fellowship for fellows interested in the critical care subspecialty alone. For those interested in dual board eligibility, their second-year program is individually designed and consists of clinical rotations required for board eligibility in the particular subspecialties. After completion of second subspecialty training, full-time research activities commence. Major topics of research interest within the Department include: • The immunopathogenesis of septic shock • Studies of immune cellular function in respiratory distress syndrome, asthma, and other forms of severe pulmonary disease • Biomarkers and novel therapies in pulmonary arterial hypertension • Biomarkers of acute cellular rejection in heart transplantation • Diagnosis and treatment of opportunistic infections • Studies of immune cellular function and therapy of AIDS • Pathogenesis and treatment of anthrax • Emerging infectious diseases • Biology and clinical effects of nitric oxide o acute lung injury o pulmonary arterial hypertension o role as transcription regulatory factor • Functional genomics of critical illness o human acute inflammation o animal model of septic shock and multiple organ failure o pulmonary arterial hypertension o solid organ transplantation o Emerging Infectious Disease o Pneumocystis Emerging infectious diseases: Animal Models of Emerging Viral Infection The overarching goal of this research is to shed light on pathogenesis of severe emerging viral infections using relevant animal models to improve approaches to prevention, diagnosis, clinical management, and targeted therapies. Some of the projects under this research are: Pathogenesis of Zika Virus Infection in Pregnant Nonhuman Primates Observational studies have shown that ZIKV crosses the human placenta and is likely responsible for a wide range of central nervous system (CNS) abnormalities in human fetuses, including microcephaly (Sarno, 2016). However, little is known about the effects of ZIKV infection when it occurs at different trimesters of pregnancy. There are also no blood tests available to diagnose fetal neurologic injuries. Fetal ZIKV infection has the potential to impact neurological development after delivery due to persistent infection, as is the case in other congenitally acquired infections such as cytomegalovirus (Picone, 2013). Understanding these features of ZIKV infection in pregnancy is vital to providing accurate counseling to potentially exposed mothers and developing potential preventative and treatment regimens. Rhesus macaques have been shown to be naturally infected by ZIKV in a manner similar to human infection (Younger, 2016) and exhibit clinical symptoms of viremia that closely mimic human symptoms of infection and result in viremia in multiple body fluids (Osuna, 2016). ZIKV infection of pregnant macaques results in fetal brain anomalies that closely mimic the observed effects in humans (Waldrof, 2016). Macaque monkeys (Macaca spp.) have also been shown to be good models for human reproduction due to genetic overlap, placental morphology (Cater, 2007), the singleton nature of birth, and the comparable levels of developmental maturity at birth (Stolte, 1975). Objective 1. Evaluate diagnostic and prognostic value of early biomarkers of fetal neurological injury in maternal serum. 2. Evaluate diagnostic and prognositic value of ultrasound and MRI imaging during gestation and postnatally. 3. Characterize ZIKV pathogeneisis during gestation and postnatally following early versus late trimester infection. I. Scope of Work The purpose of this correspondence is to request the purchase of implantable telemetry devices from Data Science International (DSI). DSI is the sole manufacturer of DSI technology for physiologic monitoring platforms, associated software and devices for all species. II. Delivery Schedule The Company shall deliver the Telemetry Devise at the National institute of Health, Clinical Center, Critical Care Medicine Department for which includes Installation and training instruction. Capability Statement is to include: Information regarding respondents; (a) including their availability, experience and informal and other training; (b) current in-house capability to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts; references, and other related information: • Respondents, DUNS number, organization name, address, point of contract, and size and type of business (e.g.8(a), HUBZone, etc) pursuant to the applicable NAICS code; • Respondents; technical and administrative points of contract including names, titles addresses, telephone and fax numbers and email addresses; • Respondents must respond to this notice by June 21, 2018 at 12:00 pm Est DISCLAIMER AND IMPORTANT NOTICES: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, a pre-solicitation synopsis and solicitation maybe published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a future solicitation. Primary Point of Contact Priscilla Abalos Contract Specialist Phone Number 301/594/5918
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/CCOPC/18-012319/listing.html)
- Place of Performance
- Address: National Institute of Health, 9000 Rockville PIke, bldg10-4D14, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04954990-W 20180616/180614230624-e948150ee1f358a2348d2303993c2fc9 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |