SOURCES SOUGHT
66 -- FluoroCore ELISPOT Analyzer for NINDS
- Notice Date
- 6/14/2018
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- SBSS-NIH-NIDA-18-4957562
- Archive Date
- 6/28/2018
- Point of Contact
- Jason Williams, Phone: 3014965985, Nancy Lamon-Kritikos, Phone: 301-480-2447
- E-Mail Address
-
Jason.Williams1@nih.hhs.gov, nancy.lamon-kritikos@nih.gov
(Jason.Williams1@nih.hhs.gov, nancy.lamon-kritikos@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. If your organization is not a small business, there is no need to respond to this announcement. For purposes of this announcement, a small business concern, in addition to meeting the small business size standard for the applicable NAICS code, is defined as "any business entity organized for profit with a place of business located in the United States or its outlying areas and that makes a significant contribution to the U.S. economy through payment of taxes and/or use of American products, material and/or labor, etc." The purpose of this notice is to obtain Capability Statements from small businesses directly addressing their ability to provide a product that meets all of the Salient Characteristics contained in the Purchase Description. In general, the Government is seeking information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining whether a small business set-aside is possible for this acquisition (or if the acquisition can be further set-aside for one of the socio-economic categories of small businesses). This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. North American Industry Classification System (NAICS) CODE: The NAICS code applicable to this requirement is 334516 - ANALYTICAL LABORATORY INSTRUMENT MANUFACTURING. The corresponding small business size standard is 1,000 or fewer employees. The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives. The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the cause, treatment, and prevention of neurological disorders. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. Statement of Need and Purpose : The purpose of this acquisition is to procure a FluoroCore ELISPOT Analyzer for the Viral Immunology Section (VIS). This platform will enable the quantification of cell-mediated immune responses, a critical capability in the field of viral immunology. Enzyme-linked immunosorbent spot-forming cell assay (ELISPOT) is used to quantify cytokine producing T cells in blood samples. This quantification of immune cell responses to various stimuli ex vivo serves as a correlate of in vivo precursor frequency. The number of antigen-specific precursor T cells, as measured by the ELISPOT assay, reflects the magnitude of the immune response. These types of immunologic data are critical for assessing differences between patients and controls, and responses to therapeutic interventions, such as treatments and vaccines. Background Information and Objective: The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The VIS research focuses on the involvement of viruses in neurologic disorders, particularly dysregulated immune responses to viruses in patients with neurological diseases compared to healthy controls. An ELISPOT analyzer will enable the use of ELISPOT as a tool to enumerate antigen-specific immune responses in various patient populations. Generic Name of Product : ELISPOT Analyzer SAMPLE PRODUCT - BRAND NAME OR EQUAL REQUIREMENT: Trade Name: ImmunoSpot® Brand Name: CTL Analyzers ImmunoSpot® S6 FluoroCore Analyzer Manufacturer: ImmunoSpot Model, type, catalog and other parts/numbers: Catalog #S6FLC12 This is a Brand Name or Equal requirement. Products other than the specific item above are acceptable, but must meet all of the salient characteristics contained in the Salient Characteristics section below: Salient characteristics Contractor shall provide the NINDS VIS with one (1) FluoroCore Analyzer that meets the following specifications: a)System must deliver conventional ELISPOT with white light and fluorescent applications. b)Equipment must be able to correctly scan and analyze FluoroSpot assays up to 3-colors. c)Equipment must be able to correctly scan and analyze ELISPOTs including three-color enzymatic ELISPOTs that measure polyfunctional cells. d) Instrument must be equipped with all of the following light sources: a.LED-based fluorescent illumination b.LED-based visible top lighting c.Uniform planar visible backlighting e)Analyzer must employs up to three unique fluorescent light source combinations with matching filters permits selective activation of fluorochromes without color bleeding and the need for compensation. f)System shall be able to scan and count 8-samples of live/dead lymphocytes in a single run and generate a viability report with resuspension volumes. g)Instrument must have a dedicated software platform to measure cytotoxicity in 96-well format with subject-specific "kill curves". h)Cytotoxicity software must be adjustable to enable users to select custom profiles in order to use their own dyes to measure cell death. i)System must come with an actual ELISPOT Qualification plate. j)Instrument shall also come supplied with a multi-color fluorescent bead Qualification slide with automated qualification routine in the software. k)System must include an optimized lens apparatus permitting the capture of 384, 96, 48 and 24 well plates l)ELISPOT reader camera must be able to acquire 10 megapixel images. m)Analyzer must be able to correctly scan/count over 11,000 spots per well. n)Equipment must have a footprint that fits on a countertop 3' x 3' with computer included within this space. o)System must include a retractable keyboard tray and integrated monitor. p)Instrument must be compatible with 50-plate stacker unit with de-lidding capability. q)Equipment must come with a minimum of a one year warranty. r)Warranty and service should be performed on site. Scanning Services shall be offered free of charge until Analyzer is repaired. s)System must be compatible with S6 FluoroCore Analyzer scanning software. Quantity : One (1) FluoroCore ELISPOT Analyzer Contract Type: A firm-fixed price type contract is anticipated for this requirement consistent with commercial practices. Delivery Schedule: The contractor shall deliver, install the equipment, and provide training for use within 30 days after receipt of order. Delivery must be FOB destination and include inside delivery. Delivery Location: The equipment shall be delivered and installed between the hours of 8:00am and 5:00 pm, Eastern Standard Time at: National Institutes of Health Bldg 10, Rm 5C103 10 Center Drive, MSC 1400 Bethesda, MD 20892. Warranty : Contract shall provide a one (1) year service and warranty. All products shall be warranted to be free from material defects in workmanship or material under normal use and service for the one year warranty period. Capability Statement / Information Sought: Small business Contractors that believe they possess the ability to provide the required products should submit documentation of their ability to meet the project requirements, addressing the Salient Characteristics contained in this announcement (a generic marketing brochure would likely not be sufficient to demonstrate a source's capability to meet the stated requirements) to the Contracting Officer. Contractors should also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information and if applicable, Federal Supply Schedule (FSS) contract number. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration definitions and guidelines. Additionally, please indicate the country of manufacture of the product your organization can offer to meet the stated requirements. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the Small Business Sources Sought notice number. All capability statements sent in response to this Small Business Sources Sought Notice must be submitted electronically (via email) to Jason Williams, Contracting Officer, at willjas@nida.nih.gov. All responses must be received by the specified due date and time in order to be considered. The response must be received on or before June 25, 2018 at 5:00 PM EST. Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price contract.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/SBSS-NIH-NIDA-18-4957562/listing.html)
- Place of Performance
- Address: Contractor's facility, Installation to occur at the National Institutes of Health main campus in Bethesda, MD, United States
- Record
- SN04955874-W 20180616/180614231012-4b62e7f022eb6c7c7a4474adae6c8310 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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