SOLICITATION NOTICE
66 -- Transendothelial Electrical Resistance (TEER) 96-Well System
- Notice Date
- 8/24/2018
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- NIHDA201800438
- Archive Date
- 9/22/2018
- Point of Contact
- Mark E. McNally, Phone: (301) 827-5869, Jeffrey Schmidt, Phone: (301) 402-1488
- E-Mail Address
-
mcnallyme@mail.nih.gov, schmidtjr@mail.nih.gov
(mcnallyme@mail.nih.gov, schmidtjr@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- INTRODUCTION PURSUANT TO FAR Subpart 5.2-Synopses of Proposed Contract Actions, THIS IS A PRE-SOLICITATION NOTICE OF A PROPOSED CONTRACT TO ACTION. THIS IS A PRE-SOLICITATION NON-COMPETITIVE NOTICE OF INTENT TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) intends to award a purchase order to Applied Biophysics, Inc., 185 Jordan Road, Troy, NY 12180, for a Transendothelial Electrical Resistance (TEER) 96-Well System. Applied BioPhysics produces a commercially-available 24-well TEER system. Applied Biophysics will develop and deploy a "TEER96" impedance measuring apparatus designed to use Millipore 96 well cell culture insert plates for simultaneous measurement of 96 wells. This device will be developed/scaled based on the TEER24 technology. Though several vendors market TEER systems, only Applied BioPhysics provides the benefits of 96-well scale with simultaneous measurement. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 1,000 employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses of the Federal acquisition Requlation (FAR) in effect through the Federal Acquisition Circular (FAC) 2005-99, dated July 16, 2018. STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source. DESCRIPTION OF REQUIREMENT Project Description One (1) Transendothelial Electrical Resistance (TEER) 96-Well System ("TEER 96"). The completed turnkey system needs to consist of a Dipping Pin Platform which connects through a Docking Adapter to the TEER 96 Station that will be designed to be operable within the cell culture incubator. The custom electronics of this Station will be connected to a Station Controller that is outside the incubator and connected to a PC which controls all aspects of data acquisition and processing. This instrument will be used to quality control transwell plates for conducting drug screenings at NCATS. Salient Characteristics The TEER 96 needs to include the following: • One (1) TEER 96 measurement system with: o Millipore 96 well culture insert plates and capability of simultaneous measurement of all 96 wells. o A transwell system with an intact monolayer of cells that does not allow paracellular diffusion across the transwell. o Continuous long-term measurement of TEER from under 10 to 10,000 ohm cm2 in up to 96 wells. o Fast barrier function dynamics that can be monitored. o Accurately measures Endothelial and Epithelial barrier function. o Real time visualization of TEER, control of sampling rate. o Ability to export data to Excel or other statistical programs. o Data output in CSV or graphical (JPEG, TIFF). o Gold electrodes. o Windows 10 OS. • Two (2) Dipping Pin Platform assemblies (one serving as a spare). • One (1) Docking Adapter board with ribbon cable connector to the TEER 96 Station. • One (1) TEER Station Controller. • One (1) set of Cables and power supply. • One (1) PC to control all aspects of data acquisition and processing. • One (1) Control and acquisition software customized for 96 well TEER measurement with data output via a CSV file. Purpose and Objectives To create and deliver a custom device (TEER 96) that can simultaneously measure electrical resistance in all 96 wells of a plate. This purchase will allow a team of scientists at NCATS to implement higher-throughput determinations of drug transport. Delivery Within one hundred eighty (180) days after receipt of order. CLOSING STATEMENT This synopsis is not a solicitation and not a request for competitive quotes. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Responses to this notice must include sufficient information to establish the interested parties' bona fide capabilities of providing the product or service. The price quote shall include: total price, delivery date after receipt of order, and any other information or factors that may be considered in the award decision. Such factors may include: (i) technical capability of the item offered to meet the Government requirement; (ii) price; and (iii) past performance (see FAR 15.304). Technical and past performance, when combined, are significantly more important than cost or price. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by 5:00 PM Eastern Time, Friday, September 7, 2018, and reference number NIHDA201800438. Responses must be submitted electronically to Contract Specialist Mark McNally at mcnallyme@mail.nih.gov. Faxed responses will not be accepted. Contracting Office Address: 6001 Executive Blvd Room 3287, MSC 9534 Bethesda, MD 20892-9534 All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/NIHDA201800438/listing.html)
- Record
- SN05054751-W 20180826/180824230823-24e5a8299475a0c5a6b350cbbf8b4640 (fbodaily.com)
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