SPECIAL NOTICE
A -- Cooperative Research and Development Agreement (CRADA) Opportunity for Developing Protein Nanoparticles for the Display of Viral Epitopes for Vaccine Use
- Notice Date
- 1/9/2019
- Notice Type
- Synopsis
- NAICS
- 54171
— Research and Development in the Physical, Engineering, and Life SciencesT
- Contracting Office
- Office of Acquisitions 5601 Fishers Lane 3rd Floor, MSC 9821 Bethesda MD 20892
- ZIP Code
- 20892
- Solicitation Number
- NIAID-TTIPO-2016-032
- Response Due
- 4/9/2019
- Point of Contact
- Jenish R. Patel, Ph.D., Senior Technology Transfer and Patent Specialist, Phone 2406692894
- E-Mail Address
-
jenish.patel@nih.gov
- Small Business Set-Aside
- N/A
- Description
- SUMMARY: The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health is announcing an opportunity for a Cooperative Research and Development Agreement (CRADA) for developing protein nanoparticles for the display of viral epitopes for vaccine use. The NIAID seeks to enter into a CRADA with one or more biotechnology or biomedical companies to use protein nanoparticles developed by NIAID for the purpose of vaccine use with one of more of the following capabilities: (i) produce scaled- up purified recombinant protein nanoparticles; (ii) carry out immunogenicity studies in animal models to (a) measure antibody levels/titers elicited by nanoparticles, (b) measure neutralization capacity of antibodies to a panel of influenza viruses, and (c) measure hemagglutination inhibition by antibodies; (iii) produce hydridomas and/or cDNA clones of neutralizing antibody genes elicited by protein nanoparticles; (iv) produce quantities of antibodies sufficient for challenge and protection studies in animal models; (v) carry-out animal challenge and protection studies with influenza viruses and nanoparticles and generate immunological data such as antibody titers, survival curves, and HAI titers; (vi) if the animal data are promising, generate clinical grade materials; and (vii) support clinical studies. NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (09-JAN-2019); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT 877-472-3779 or fbo.support@gsa.gov REGARDING THIS ISSUE.
- Web Link
-
Link To Document
(https://www.fbo.gov/spg/HHS/NIH/NIAID/NIAID-TTIPO-2016-032/listing.html)
- Record
- SN05190517-F 20190111/190109230019 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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