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FBO DAILY - FEDBIZOPPS ISSUE OF JANUARY 11, 2019 FBO #6258
SPECIAL NOTICE

A -- Cooperative Research and Development Agreement (CRADA) Opportunity for Developing Protein Nanoparticles for the Display of Viral Epitopes for Vaccine Use

Notice Date
1/9/2019
 
Notice Type
Synopsis
 
NAICS
54171 — Research and Development in the Physical, Engineering, and Life SciencesT
 
Contracting Office
Office of Acquisitions 5601 Fishers Lane 3rd Floor, MSC 9821 Bethesda MD 20892
 
ZIP Code
20892
 
Solicitation Number
NIAID-TTIPO-2016-032
 
Response Due
4/9/2019
 
Point of Contact
Jenish R. Patel, Ph.D., Senior Technology Transfer and Patent Specialist, Phone 2406692894
 
E-Mail Address
jenish.patel@nih.gov
 
Small Business Set-Aside
N/A
 
Description
SUMMARY: The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health is announcing an opportunity for a Cooperative Research and Development Agreement (CRADA) for developing protein nanoparticles for the display of viral epitopes for vaccine use. The NIAID seeks to enter into a CRADA with one or more biotechnology or biomedical companies to use protein nanoparticles developed by NIAID for the purpose of vaccine use with one of more of the following capabilities: (i) produce scaled- up purified recombinant protein nanoparticles; (ii) carry out immunogenicity studies in animal models to (a) measure antibody levels/titers elicited by nanoparticles, (b) measure neutralization capacity of antibodies to a panel of influenza viruses, and (c) measure hemagglutination inhibition by antibodies; (iii) produce hydridomas and/or cDNA clones of neutralizing antibody genes elicited by protein nanoparticles; (iv) produce quantities of antibodies sufficient for challenge and protection studies in animal models; (v) carry-out animal challenge and protection studies with influenza viruses and nanoparticles and generate immunological data such as antibody titers, survival curves, and HAI titers; (vi) if the animal data are promising, generate clinical grade materials; and (vii) support clinical studies. NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (09-JAN-2019); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT 877-472-3779 or fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Web Link
Link To Document
(https://www.fbo.gov/spg/HHS/NIH/NIAID/NIAID-TTIPO-2016-032/listing.html)
 
Record
SN05190517-F 20190111/190109230019 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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