SOURCES SOUGHT
66 -- 2100 Bioanalyzer Instrument or Brand Equal
- Notice Date
- 5/6/2019
- Notice Type
- Synopsis
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- 6001 Executive Boulevard Room 4211, MSC 9559 Bethesda MD 20892-9559
- ZIP Code
- 20892-9559
- Solicitation Number
- 75N95019Q00158
- Response Due
- 5/13/2019
- Point of Contact
- Mark E. McNally, Contract Specialist, Phone (301) 827-5869, - Jeffrey Schmidt, Contracting Officer, Phone (301) 402-1488
- E-Mail Address
-
mark.mcnally@nih.gov, jeffrey.schmidt@nih.gov
- Small Business Set-Aside
- N/A
- Description
- This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives. Launched in April 2018, the NIH HEAL (Helping to End Addiction Long-term) Initiative is a trans-NIH effort to advance national priorities in addressing the opioid crisis through science. As part of the initiative, NIH developed a plan to bolster research to enhance pain management strategies and improve treatments for opioid misuse and addiction. With HEAL support, the National Center for Advancing Translational Sciences (NCATS) is providing a suite of translational science resources and expertise to investigators working on opioid and pain research. NCATS strives to be at the leading edge of technology in order to advance translational science. NCTAS applies high-throughput screening and discovery to the development of small molecule chemical probes, for use in the study of protein and cell functions, and biological processes relevant to physiology and disease. Antibodies are now a well-established therapeutic modality but in contrast to small molecules have not been explored within NCATS to-date. For HEAL, antibodies may represent a key therapeutic alternative in cases where a small molecule may not be possible to develop or where certain superior pharmacokinetic properties of antibodies (such as a lot longer plasma half-life compared to small molecule) make them the more appropriate therapeutic modality. Obtaining the needed equipment will enable NCATS to begin the process of discovery and development of antibodies as a key therapeutic class. This request will enable NCATS increase the capability and applications to generate the more robust, high sensitivity and quantitative data to better serve the HEAL Initiative. NCATS DPI section is requesting to purchase an Agilent 2100 Bioanalyzer Instrument or brand equal for use in the DPI biology laboratory, located at 9800 Medical Center Drive. The current protocol for antibody discovery by phage display involves multiple DNA cloning and protein purification steps. These procedures require multiple steps such as electrophoretic separation, staining, de-staining, detection and quantification. These steps are time consuming and error prone and importantly, require different reagents, protocols and equipment according to the type of molecule being analyzed (nucleic acid vs. protein). The 2100 Bioanalyzer Instrument allows for fast and automated electrophoresis and quantification of DNA, RNA and protein. NCATS strives to be at the leading edge of technology in order to advance translational science. Acquisition of the 2100 Bioanalyzer system or brand equal will allow DPI to efficiently perform antibody screening as well as feel the needs for any molecular biology related projects. Purpose and Objectives: The purchase of an Agilent 2100 Bioanalyzer Instrument or brand equal is being requested by the DPI biology group in order to provide a fast and accurate method for quality control of DNA, RNA and protein required to support antibody discovery and characterization. The instrument provides fast and automated electrophoresis analysis of nucleic acids and proteins, the ability to manage and analyze digital data providing objective information about concentration, size, integrity, and purity. The system reduces overall time, space and volume requirements, and allows integration of many workflow steps, such as separation, staining, de-staining, and detection. Project requirements: Agilent 2100 Bioanalyzer Instrument or brand equal for automated electrophoresis of DNA, RNA and protein. The purchase includes a 2100 Expert SW laptop bundle and 2100 Bioanalyzer System RoHS Compliant. The brand equal items must be equivalent to the following: Product Name: 2100 Bioanalyzer Instrument Manufacturer: Agilent Technologies Product Number: G2939BA Quantity: One (1) Product Name: 2100 Expert SW laptop bundle Manufacturer: Agilent Technologies Product Number: G2953CA Quantity: One (1) Product Name: 2100 Bioanalyzer System RoHS Compliant Manufacturer: Agilent Technologies Product Number: SYS-BI-2100 Quantity: One (1) Salient Characteristics: The brand equal items must meet the following salient physical, functional, or performance characteristics of the brand-name item to be acceptable for award: 2100 Bioanalyzer Instrument, Product Number G2939BA: - The instrument provides electrodriven flow and separation of biomolecules through interconnected networks of microchannels. The fast electrophoresis analysis of DNA, RNA, or proteins, results in digital data providing concentration, size, integrity, and purity in a timely manner. - The system reduces overall space and volume requirements, and allows integration of many workflow steps, such as separation, staining, de-staining, and detection, significantly streamlining the process. - The 2100 Bioanalyzer system is an established automated electrophoresis tool for the sample quality control of biomolecules. Minimal sample volumes are required for an accurate result, and the data may be exported in a many different formats for ease-of-use. - Replaceable electrode cartridges that can be easily exchanged for contamination-free switching between methods. - The system features minimum exposure to hazardous materials to ensure operator safety. - Finally, this instrument would be available to use at DPI for any other molecular biology application (not only phage display) that requires colony picking. - Line Frequency: 50-60 Hz. - Weight: 10 kg. - Power Consumption: 60 VA. - Ambient Temperature: 15-27 degrees C.. - Safety Standards: Installation Category II, Pollution Degree 2, Laser Class 1. - Line Voltage: 100-240 VAC. 2100 Bioanalyzer Expert SW Laptop Bundle, Product Number G2953CA - HP Compaq laptop. - Pre-installed 2100 expert software and instrument control license. - Functionality allows for setting: electro- phoresis and flow cytometry set. - Configuration: USA. 2100 Bioanalyzer System RoHS Compliant, Product Number SYS-BI-2100 - Compliant with USA RoHS directives. - Extended two-year warranty. Delivery will be f.o.b. destination to Rockville, MD 20850 and will include inside delivery and installation. Anticipated award date: May 2019. Other important considerations: This is a brand-name or equal requirement. Information sought: Responses to this notice must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The response shall include: the unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. All responses to this notice must be submitted electronically to Contract Specialist Mark McNally, mark.mcnally@nih.gov. Responses must be received by 11:00 a.m. Eastern Daylight Time, Monday, May 13, 2019. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (06-MAY-2019); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT 877-472-3779 or fbo.support@gsa.gov REGARDING THIS ISSUE.
- Web Link
-
Link To Document
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/75N95019Q00158/listing.html)
- Record
- SN05302446-F 20190508/190506230019 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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