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FBO DAILY - FEDBIZOPPS ISSUE OF JULY 03, 2019 FBO #6431
MODIFICATION

66 -- Protein Stability Detection

Notice Date

7/1/2019
 

Notice Type

Modification
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

3900 NCTR Road, HFT-320 Bldg 50 | Rm 421 Jefferson AR 72079
 

ZIP Code

72079
 

Solicitation Number

FDA-SOL-1214139
 

Response Due

7/11/2019
 

Point of Contact

ROOSEVELT D. WALKER, CONTRACT SPECIALIST, Phone 8705437405
 

E-Mail Address

roosevelt.walker@fda.hhs.gov
 

Small Business Set-Aside

Total Small Business
 

Description

This is a combined synopsis/solicitation for commercial items prepared in accordance with the Federal Acquisition Regulation (FAR) format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. It is the Government's intent to issue a Firm Fixed Priced Purchase Order in accordance with FAR Part 13. The solicitation number is FDA_SOL_1214139. This solicitation is issued as a Request for Quote (RFQ). The solicitation document and incorporated provisions and clauses in effect through the Federal Acquisition Circular 2019-02 dated May 06, 2019. The appropriate North American Industry Classification System (NAICS) Code is 334516 Analytical Laboratory Instrument Manufacturing. The Small Business Size standard is 1,000 employees. This requirement is solicited as a Total set-aside for small business competition. Statement of Work The FDA/CBER requires for a label free Protein Stability Detection instrument. It is critical to analyze both their structure and their function. To determine whether a protein is functional and able to bind its interaction partner or ligand. The instrument shall examine protein-ligand interactions by performing a label-free thermal shift analysis. Suitable ligands can be varied and diverse, ranging from ions, sugars and small molecules to nucleotides and lipids. By recording and comparing highly precise unfolding profiles, ligand-induced changes in the protein's stability as monitored by fluorescence properties can be derived to conclude binding. In this way, the system allows for evaluating protein functionality within minutes, and can be integrated in purification workflows or assay development routines. NOTE: THIS NOTICE WAS NOT POSTED TO FEDBIZOPPS ON THE DATE INDICATED IN THE NOTICE ITSELF (01-JUL-2019); HOWEVER, IT DID APPEAR IN THE FEDBIZOPPS FTP FEED ON THIS DATE. PLEASE CONTACT 877-472-3779 or fbo.support@gsa.gov REGARDING THIS ISSUE.
 

Web Link

Link To Document
(https://www.fbo.gov/spg/HHS/FDA/NCTR/FDA-SOL-1214139/listing.html)
 

Place of Performance

Address: US Food and Drug Administration Center for Biologics Evaluation and Research (CBER) 10903 New Hampshire Avenue Building 52/72, Room G362 Silver Spring, MD

Zip Code: 20993

Country: US
 

Record

SN05357576-F 20190703/190701230052 (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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