SOLICITATION NOTICE
66 -- Rat Head Coils
- Notice Date
- 9/1/2019
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- HHS-NIH-NIDA-19-010472-CSS
- Point of Contact
- Debra C. Hawkins, Phone: 301-827-7751
- E-Mail Address
-
debra.hawkins@nih.gov
(debra.hawkins@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- (i)This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii)The solicitation number is HHS-NIH-NIDA-19-010472-CSS and the solicitation is issued as a Request for Quotation (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures and FAR Part 12-Acquisition of Commercial Items. This acquisition is not expected to exceed the simplified acquisition threshold. (iii) This solicitation incorporates the provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2019-05, effective August 13, 2019. (iv) The associated North American Industry Classification System (NAICS) code: 334516-Analytical Laboratory Instrument Manufacturing, Size Standard: 1,000 Employees. (v) Rat Head Coils (vi) This action is to purchase rat head coils and animal beds brand-name or equal to the items manufactured by Rapid MR International, LLC, 1500 Lake Shore Drive, Suite 310, Columbus, Ohio 43204. Specifically, (1) item number: V-XQS-HL-094, 31P 1H volume resonator; (2) item number: P-X02LE-094, 31P surface coil for rat brain, (3) item number: O-XL-HL-094, 31P 1H dual tuned surface coil for rat brain; (4) item number: O-XL-HL-094, 23Na 1H dual tuned surface coil for rat brain; (5) item number: LHRXGS-01796, Animal holder for obese rats, and (6) item number: P-H04LE-094,1H phased array for rat brain (large rats). Background / Purpose / Objective: The National Institute of Aging (NIA) Intramural Research Program (IRP) requires custom-built MRI coils and an animal bed for rat brain studies using NIA's new Bruker Biospec 94/20 USR scanner. While Bruker sells generic coils and beds for rats of average size, our longitudinal studies require equipment that will accommodate older, very large rats weighing in excess of 1 kg. Such hardware, including suitable proton (1H) head coils, is non-standard and must be custom-built. Included in this requisition are rat brain coils for observing phosphorus-31 (31P) and sodium-23 (23Na) nuclei. 31P magnetic resonance spectroscopy (MRS) is used to identify bioenergetic deficits, including those associated with hypoperfusion and neuronal death, in neurodegenerative diseases such as Alzheimer's disease (AD) and vascular dementia. Further, 23Na MRS allows us to detect neuronal death, white matter degradation and edema associated with neurodegenerative diseases such as Alzheimer's disease and vascular dementia. This capability will augment our translational research program on the etiology of these diseases in humans. The specifications / salient characteristics for the Proton, phosphorus-31 and sodium-23 coils and animal bed for brain MRI of obese rats shall include interoperable components for proton, phosphorus-31 and sodium-23 NMR and MRI of the rat brain as follows: (1) 31P 1H volume resonator: (a) capable of transmitting and receiving at the proton (1H frequency of a 9.4 T MRI scanner (400.3 MHz) to acquire reference images of the rat brain for phosphorus voxel placement and registration; (b) capable of transmitting and receiving at the phosphorus-31 (31P) frequency of a 9.4T MRI scanner (162.0 MHz) to acquire a phosphorus-31 spectrum of a selected brain region; (c) an inner diameter of at least 85 mm to comfortably fit the body of rats weighing up to 1.2 kg; (d) that fit within Bruker B-GA12S-HP MRI gradient coil - an outer diameter of 112 mm or less; (e) each channel must have an active coil length of at least 10 cm to scan the entire brain in the rostral-caudal direction with sufficient radio-frequency field (B1+ and B1-) homogeneity; (f) must have a radio-frequency and DC electrical interface compatible with the Bruker Biospec Neo MRI console; (g) must include probe description files and any other code needed to interface the coil to the scanner's acquisition software (ParaVision 7); (h) must incorporate quadrature polarization on the phosphorus-31 channel to maximize efficiency for spin excitation and signal detection; (i) must be capable of exciting and receiving a proton NMR spectrum of a standard 85% phosphoric acid phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to produce proton images of sufficient quality to allow reliable phosphorus voxel placement; (j) must demonstrate ability to excite phosphorus-31 (31P) nuclei in a standard 85% phosphoric acid phantom with flip angles from 10 degrees to 270 degrees with an error of no more than 5% from the theoretical sinusoidal dependence of integrated signal on flip angle. This is needed to prevent artifacts in spin-echo and stimulated-echo experiments in which 31P must be excited with precise flip angles; and (k) must support active decoupling on the 31P channel so that the volume coil can be used in transmit-only mode with a receive-only 31P surface coil or array. (2) 31P Receive-only Surface Coil for Rat Brain: (a) Must be capable of receiving at the phosphorus-31 (31P) frequency of a 9.4T MRI scanner (162.0 MHz) to acquire a phosphorus-31 spectrum of a selected brain region; (b) The surface of the coil housing touching the rat's head should be curved (i.e. anatomically-shaped) with an inner diameter of at least 36 mm to comfortably fit the head of rats weighing up to 1.2 kg; (c) Must mount on top of obese rat bed described below so that the center of the coil is positioned at the center of the rat's brain while the animal is anesthetized and fixed to the tooth bar in the rat bed; (d) Each channel must have an active coil length of at least 38 mm to scan the entire brain in the rostral-caudal direction with sufficient radio-frequency field (B1-) homogeneity; (e) The coil must receive signal over a radial angle of at least 180 degrees in order to cover the entire rat brain in the anterior-posterior direction; (f) Must have a radio-frequency and DC electrical interface compatible with the Bruker Biospec Neo MRI console; (g) Must include probe description files and any other code needed to interface the coil to the scanner's acquisition software (ParaVision 7); (h) Must receive a phosphorus-31 signal from a standard 85% phosphoric acid phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to achieve adequate sensitivity in rat brain spectroscopy experiments; and (i) Must support active decoupling so that the receive-only 31P surface coil can be used with the above 1H/31P volume coil in transmit-only mode. (3) 1H/31P Transmit-Receive Surface Coil for Rat Brain: (a) Must be capable of transmitting and receiving at the proton (1H frequency of a 9.4 T MRI scanner (400.3 MHz) to acquire reference images of the rat brain for phosphorus voxel placement and registration; (b) Must be capable of transmitting and receiving at the phosphorus-31 (31P) frequency of a 9.4T MRI scanner (162.0 MHz) to acquire a phosphorus-31 spectrum of a selected brain region; (c) The surface of the coil housing touching the rat's head should be curved (i.e. anatomically-shaped) with an inner diameter of at least 36 mm to comfortably fit the head of rats weighing up to 1.2 kg; (d) Must mount on top of obese rat bed described below so that the center of the coil is positioned at the center of the rat's brain while the animal is anesthetized and fixed to the tooth bar in the rat bed; (e) Each channel must have an active coil length of at least 38 mm to scan the entire brain in the rostral-caudal direction; (f) The coil must transmit and receive 1H and 31P signals over a radial angle of at least 180 degrees in order to cover the entire rat brain in the anterior-posterior direction; (g) Must have a radio-frequency and DC electrical interface compatible with the Bruker Biospec Neo MRI console; (h) Must include probe description files and any other code needed to interface the coil to the scanner's acquisition software (ParaVision 7); (i) Must be capable of exciting and receiving a proton NMR spectrum of a standard 85% phosphoric acid phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to produce proton images of sufficient quality to allow reliable phosphorus voxel placement; and (j) Must be capable of exciting and receiving a phosphorus-31 NMR spectrum of a standard 85% phosphoric acid phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to achieve adequate sensitivity in rat brain spectroscopy experiments. (4) 1H/23Na Transmit-Receive Surface Coil for Rat Brain: (a) Must be capable of transmitting and receiving at the proton (1H frequency of a 9.4 T MRI scanner (400.3 MHz) to acquire reference images of the rat brain for sodium voxel placement and registration; (b) Must be capable of transmitting and receiving at the sodium-23 (23Na) frequency of a 9.4T MRI scanner (105.9 MHz) to acquire a 23Na spectrum of a selected brain region; (c) The surface of the coil housing touching the rat's head should be curved (i.e. anatomically-shaped) with an inner diameter of at least 36 mm to comfortably fit the head of rats weighing up to 1.2 kg; (d) Must mount on top of obese rat bed described below so that the center of the coil is positioned at the center of the rat's brain while the animal is anesthetized and fixed to the tooth bar in the rat bed; (e) Each channel must have an active coil length of at least 38 mm to scan the entire brain in the rostral-caudal direction; (f) The coil must transmit and receive 1H and 23Na signals over a radial angle of at least 180 degrees in order to cover the entire rat brain in the anterior-posterior direction; (g) Must have a radio-frequency and DC electrical interface compatible with the Bruker Biospec Neo MRI console; (h) Must include probe description files and any other code needed to interface the coil to the scanner's acquisition software (ParaVision 7); (i) Must be capable of exciting and receiving a proton NMR spectrum of a standard 1X DPBS phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to produce proton images of sufficient quality to allow reliable sodium voxel placement; and (j) Must be capable of exciting and receiving a soidum-23 NMR spectrum of a standard 1X DPBS phantom with a minimum signal-to-noise ratio of 20:1 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to achieve adequate sensitivity in rat brain spectroscopy experiments. (5) Animal bed for obese rats: (a) Must have an inner diameter of at least 82 mm to comfortably fit the body of rats weighing up to 1.2 kg; (b) Must slide completely through the above 1H/31P volume coil - an outer diameter of 86 mm or less satisfies this requirement; (c) Must include anesthesia mask with bite bar and ear bars for stereotaxic fixation of rat head during brain scanning. Each of these items should move independently and then be capable of locking in position to accommodate rats of various sizes up to 1.2 kg; (d) Must couple with Bruker ManPac slider assembly so that bed can be positioned reproducibly along the Z axis of the MRI magnet; and (e) Length from front of bed to field center should be 45 +/- 1 cm so that a rat mounted in the bed can be placed with the center of its brain at the center of the magnet using the Bruker ManPac apparatus. (6) Proton Receive-only Array Coil for Rat Brain: (a) Must be capable of receiving at the proton (1H) frequency of a 9.4T MRI scanner (400.3 MHz) to acquire proton images of the rat brain; (b) The surface of the coil housing touching the rat's head should be curved (i.e. anatomically-shaped) with an inner diameter of at least 36 mm to comfortably fit the head of rats weighing up to 1.2 kg; (c) Must mount on top of obese rat bed described below so that the center of the coil is positioned at the center of the rat's brain while the animal is anesthetized and fixed to the tooth bar in the rat bed; (d) The coil array must have an active length of at least 38 mm to scan the entire brain in the rostral-caudal direction with sufficient radio-frequency field (B1-) homogeneity; (e) The coil must receive signal over a radial angle of at least 180 degrees in order to cover the entire rat brain in the anterior-posterior direction; (f) Coil must contain at least four array and no more than eight elements to permit scan acceleration using parallel imaging techniques on a Bruker Biospec Neo console equipped with eight receive channels; (g) Must have a radio-frequency and DC electrical interface compatible with the Bruker Biospec Neo MRI console; (h) Must include probe description files and any other code needed to interface the coil to the scanner's acquisition software (ParaVision 7); (i) Must receive a proton signal from a standard 50 ml Bruker rat brain phantom with a minimum signal-to-noise ratio per unit volume of 3000 mm-3 in one scan and a maximum line width (full width at half maximum) of 10 Hz in order to achieve adequate sensitivity in rat brain imaging and spectroscopy experiments; and (j) Must support active decoupling so that the receive-only 1H array can be used with the Bruker 86 mm quadrature volume coil in transmit-only mode. (vii) Government's Anticipated Delivery: Within Five (5) Weeks After Receipt of Order (ARO). Delivery Point: FOB Destination. Delivery Location: National Institutes of Health, National Institute on Aging, Baltimore, Maryland 21224. The successful offeror shall coordinate delivery arrangements with the customer prior to shipment. The Loading Dock hours are as follows: 8:00 am to 4:30 pm Eastern Time, Monday through Friday except on Federal holidays. All products delivered must contain a Packing Slip (with serial numbers as applicable). (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The factors shall be used to evaluate offers are the unique technical and performance capabilities and cost. Technical and past performance, when combined, are significantly more important than cost or price. (x) Offerors are advised to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer or certify that their Representations and Certifications - Commercial Items are accurate and current in the System for Award Management (SAM). (xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. (xiii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xiv) Defense Priorities and Allocations System (DPAS) and assigned rating, is not applicable to this solicitation. (xv) All quotations or offers are due 12:00 Noon, Eastern Time, on September 6, 2019, and must reference the solicitation number noted herein. Quotations or offers must be submitted electronically to the contact person identified herein at debra.hawkins@nih.gov. Fax responses will not be accepted. (xvi) For information regarding this solicitation contact: Debra C. Hawkins Contractor, Acquisition Policy Analyst II, at 301-827-7751.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/HHS-NIH-NIDA-19-010472-CSS/listing.html)
- Place of Performance
- Address: National Institutes of Health, National Institute on Aging, Baltimore, Maryland, 21224, United States
- Zip Code: 21224
- Zip Code: 21224
- Record
- SN05427495-W 20190903/190903143140-0ea900db325d620476d2017cdbc80d2d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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