MODIFICATION
66 -- Davis Rig Technology Brief Access Lick Apparatus
- Notice Date
- 6/16/2020 12:22:46 PM
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-CSS-20-006744
- Response Due
- 6/30/2020 9:00:00 AM
- Archive Date
- 12/30/2020
- Point of Contact
- Debra C. Hawkins, Phone: 3018277751
- E-Mail Address
-
Debra.Hawkins@nih.gov
(Debra.Hawkins@nih.gov)
- Description
- (I) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (II) The solicitation number is HHS-NIH-NIDA-NIA-CSS-20-006744 and the solicitation is issued as a Request for Quotation (RFQ). This solicitation is issued as non-competition. This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13�Simplified Acquisition Procedures; FAR Subpart 13.5�Simplified Procedures for Certain Commercial Items; and FAR Part 12�Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. �(iii) This solicitation incorporates the provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2020-06, effective June 5, 2020. �(iv) The associated North American Industry Classification System (NAICS) code: 334516�Analytical Laboratory Instrument Manufacturing; Size Standard: 1,000 Employees. � (v) Davis Rig Technology Brief Access Lick Apparatus (vi) Background Information and Objective:� National Institute on Aging (NIA), Intramural Research Program (IRP), Laboratory of Clinical Investigation, Diabetes Section, requires a Davis Rig Technology Like Apparatus for short access taste testing to assess taste perception in our insulin knockout mice. These instruments are the only apparatus currently available to test short access taste preference in mice. The Davis Rig instruments that we are currently using are over 10 years old and have been causing problems in our recent experiments.� Specifically, connections between the rig and the computer are worn and damaged, leading to difficulties in acquiring data. The new system comes complete with a computer for each rig. Three rigs are required in total so that we can collect data from several mice of the same transgenic model at the same age in a timely fashion.� The Davis Rig models that are currently used for short access taste testing in our projects are over 10 years old and have been causing problems in our recent assessment of the taste perception of our insulin knock -out mice. These are the only apparatus currently available to test short access taste preference in mice.� Connections between the rig and the computer are worn and damaged leading to difficulties in acquiring data. The new system comes complete with a computer for each rig. Three rigs are required in total in order to obtain data in a timely fashion on our models so that we can collect data from several mice of the same model at the same age. There have been significant upgrades to the system we are requesting that we require to ensure that the results we are getting are accurate. Specifically, the model that we have currently uses a motorized shutter which can trap the snout of the mouse and thus hurt the mouse. This we understand has adversely affected our data acquisition by introducing a variable we cannot control for i.e. the adverse reaction of the mouse to being hurt by the shutter and thus not wanting to return to lick yet again. The desire for a particular taste in the short access study is quantified by the number of licks that the mouse gives to the bottle with that particular taste and the motorized shutter is adversely affecting their responses. The new system comes with a gravity controlled shutter that does not trap the mouse�s snout and thus does not confound the data with this effect. The intent of this action is to purchase a Lick Access Instrument.�� The Lick Access Instrument should be brand-name or equal to the Davis Rig Brief Access Lickometer , manufactures by Med Associates, Inc., P.O. Box 319, St. Albans, VT 05478, Part MED-DAV-160M for Mouse, 16 Bottle, Legacy Version; and COM-106-NV, Intel i5-7400 3.5GHz, 16GB RAM, 1TB HDD, Windows 10 Pro 64bit equipment.� Salient characteristics.� Brief access lickometery studies assess taste preference, chemotransduction pathways, and ingestive behavior in a rapid, efficient manner.� Functional improvements from DiLog Instruments� design: (1) �Normally up� shutter mechanism (gravity instead of motor driven); and (2) Longer sipper tube to fit new plate design.� Prior to the 16 bottle setup, the most common taste response setup was the two bottle preference test, where two bottles of fluid are placed in an animal�s cage with one of taste solution (or water) and the other a different taste solution. This test is simple, doesn�t require much in the way of additional equipment, and is relatively straightforward to administer. However, such simplicity comes at the price of interpretive ability. Although taste plays a sizable role in influencing the amount and type of foods/fluids ingested (as in a 2-bottle test), other factors (such as post-ingestive events) can influence behavior. The brief access lickometer is designed to deliver taste samples and measure responses, increasing likelihood that the behavior of the animal is under orosensory control. It can also be used to assess taste preference, ingestive behavior, and chemotransduction pathways in a rapid, efficient manner as there is no dead space in stimulus delivery lines to make fluid volumes consistent across trials, as well as lick tracking without passing electrical current through the animal. It also enables measurement of both unconditioned and conditioned licking behavior to stimuli and/or can be used to train the animal with various stimuli to obtain a reward and/or avoid punishment. The Davis Rig packages contain everything needed for running brief access lickometery studies in a single subject. The eponymous Davis Rig is the only apparatus on the market to test for short access taste preferences in mice. (vii) Government's Anticipated Delivery: Within Six (6) to Eight (8) Weeks After Receipt of Order (ARO). Delivery Point: FOB Destination. Delivery Location: National Institute on Aging, 251 Bayview Boulevard, Baltimore, Maryland 21224. The successful offeror shall coordinate delivery arrangements with the customer prior to shipment. The Loading Dock hours are as follows: 8:00 am to 4:30 pm Eastern Time, Monday through Friday except on Federal holidays. All products delivered must contain a Packing Slip (with serial numbers as applicable). (viii) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. (ix) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The factors used to evaluate offers are the unique technical and performance capabilities of product and cost. Technical and past performance, when combined, are significantly more important than cost or price.� The response must also indicate the country of manufacturer. (x) Offerors are advised to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications - Commercial Items, with its offer. (xi) FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. (xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition. (xiii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xiv) Defense Priorities and Allocations System (DPAS) and assigned rating, is not applicable to this solicitation. (xv) All quotations or offers are due 12:00 Noon, Eastern Time, on June 30, 2020, and must reference the solicitation number noted herein.� Quotations or offers must be submitted electronically to the contact person identified herein at debra.hawkins@nih.gov.� Fax responses will not be accepted. (xvi) For information regarding this solicitation contact: Debra C. Hawkins Contractor, Acquisition Policy Analyst II, at debra.hawkins@nih.gov.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/0e03af9f19e846e185978e1b783df819/view)
- Place of Performance
- Address: Baltimore, MD 21224, USA
- Zip Code: 21224
- Country: USA
- Zip Code: 21224
- Record
- SN05692081-F 20200618/200616230202 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
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