SAMDaily.us | PRESOL | 65 | High throughput High Quality Direct Detection Gatan K3

SAMDAILY.US - ISSUE OF JUNE 18, 2020 SAM #6776
SOLICITATION NOTICE

65 -- High throughput High Quality Direct Detection Gatan K3

Notice Date: 6/16/2020 1:06:36 PM
Notice Type: Presolicitation
NAICS: 334516 — Analytical Laboratory Instrument Manufacturing
Contracting Office: NATIONAL INSTITUTES OF HEALTH NICHD BETHESDA MD 20817 USA
ZIP Code: 20817
Solicitation Number: NICHD-20-111
Response Due: 6/30/2020 6:00:00 AM
Archive Date: 07/15/2020
Point of Contact: Amber Harris
E-Mail Address: amber.harris@nih.gov
(amber.harris@nih.gov)
Description: �� COMBINED SYNOPSIS / SOLICITATION WORKFORM (1)�� Action Code: �Combined Synopsis/Solicitation (2)�� Date: 6/16/2020 (3)�� Year: 2020 (4)�� Contracting Office Zip Code: 20892 (5)�� Project Service Code: 6515 - MEDICAL AND SURGICAL INSTRUMENTS, EQUIPMENT, AND SUPPLIES (6)�� Contracting Office Address: 6710B Rockledge Drive Bethesda, MD 20892 (7)�� Subject/Title: High throughput High Quality Direct Detection Gatan K3 (8)�� Proposed Solicitation Number: NICHD-20-111 (9)�� Closing Response Date: 6/30/2020 (10)�� Contact Point: Amber Harris (11)�� Contract Award and Solicitation Number: TBD (12)�� Contract Award Dollar Amount: TBD (13)�� Contract Line Item Number(s): TBD (14)�� Contractor Award Date: TBD (15)�� Contractor Name: TBD (16)�� Description: (Background) (i)�� This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. �This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued.�� (ii)�� The solicitation number is NICHD-20-110 and the solicitation is issued as a request for quote (RFQ). (iii)�� The solicitation document, the incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2020-06 effective 6 MAY 2020. (iv)�� The associated NAICS code is 334516, Analytical Laboratory Instrument Manufacturing, and the small business size standard is 1,000. �The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13.5.� (v)�� The Contractor Requirements are listed below: 1.0�� PURCHASE ORDER TITLE Acquisition of a High throughput High Quality Direct Detection Gatan K3�� 2.0�� BACKGROUND Cryo-Electron Microscopy (Cryo-EM) allows researchers to determine high-resolution 3D protein structures in a more native state (sub 3 Angstrom) without the need of crystallization. In recent years the field has witnessed a boom with its application to protein structure problems. The Multi-Institute cryoEM Facility (MICEF) currently possesses a high-resolution cryo-EM microscope, Titan KriosCryo Transmission Electron Microscope, that serves ~37 users from 18 labs in the four participating Institutes and Centers (ICs). �With this high demand each user will receive time on the Krios only once every 3 months, creating a large delay in data collection and productivity. �This severely hampered the research progress of the participating research programs and associated institutions.� possible laboratory based MX capabilities available as it allows development. 3.0�� OBJECTIVE The scope of this purchase order is to purchase a K3 camera with BioQuantum Imaging capability and have it installed on the NIDDK�s existing Krios microscope. � The latest generation Direct Detection camera K3 from Gatan is significantly faster and has a larger imaging area than the current camera on the Krios (K2). �The K3 has a frame rate of 1500 frames per second (fps) compared to 400 fps for the earlier generation K2 camera, a 3.6X improvement in speed. The total pixels of the imaging area are 23.6 megapixels (5,760 x 4,092) compared to 14.4 megapixels (3,838 x 3,710) for K2, a 1.6X improvement in size. This results in a total of 6.2X improvement over the previous generation K2 camera. Therefore, upgrading the Krios to a K3 camera will more than triple the current output of the Krios and what is typically achieved in 3 days can be achieved in 1 day. This will greatly decrease the backlog of samples ready for data collection. 4.0 �� SALIENT / REQUIRED FEATURES AND SPECIFICATIONS The K3 camera will replace the current K2 camera and will be mounted to the existing energy filter on the Krios microscope therefore, the successful offeror must provide a camera that is compatible with and will attach to �the Gatan energy filter on the existing Krios cyroEM microscope. The Gatan K3 attaches to the NIDDK�s Gatan energy filter on the existing Krios cyroEM microscope. �The readout speed of a Gatan K3 Direct Detection camera (1500 fps) surpass its competitors (all below 100 fps) by a large margin. This allows for both faster data collection and higher DQE data quality in Electron Counting Mode. Electron Counting Mode is well suited for Low Dose applications like Cryo EM for which the Cryo specimen (typically protein) is very sensitive to electron beam radiation damages. The specific items the NIDDK requires are listed below: K3 Camera/Installation: Part #�� Product Name 1967.U�� BioQuantum K3 Imaging Filter Conversion Upgrade option that converts NIDDK�s existing Gatan GIF Quantum system to a K3-based energy-filtered direct detection system (963, 965, 967 upgrade to 1967) for high contrast imaging and tomography applications. Gatan installation is required. Completed to Gatan Inc.�s stated capabilities and performance specifications available at www.gatan.com/BioQuantumK3/datasheet. Part #�� Product Name 1967.T�� BioQuantun K3 Installation Includes installation and basic product training performed at the time of install. Part #�� Product Name 700.LS.1967.00.64.1�� BioQuantum K3 Suite (64-bit) Enables acquisition and analysis capabilities of the BioQuantum K3 imaging filter (64-bit, 1 license). Includes one copy for online use, and one for offline use. Optional Upgrade: Part #�� Product Name 1025.GPU�� GPU Upgrade for K3 Camera Advanced GPU-based real-time, in-line motion correction processing to avoid the need to save all raw frames to disk, dramatically reducing the data storage requirements. Part #�� Product Name 700.LS.1025.U3.64.1�� GPU Upgrade Software Suite (K3 Camera, 64-bit) Software to enable advanced GPU-based, in-line motion correction processing on the K3 camera (64-bit, 1 license). Includes one copy for online use, and one for offline use. 5.0 �� TASKS AREAS Independently, and not as an agent of the Government, the contractor shall perform all the detailed Task Areas listed below: 5.1�� Task Area 1 � Delivery � Delivery Within 18 Weeks ARO� 5.2�� Task Area 2 � Shipping Instructions � Shipping to NIH Building 13.� 6.0�� PURCHASE ORDER TYPE This Purchase Order is to be a firm fixed price.� 7.0�� INSPECTION AND ACCEPTANCE Inspection and acceptance will be performed at the place of installation - National Institutes of Health, NIDDK, 9000 Rockville Pike, Maryland 20892. (vi)�� This requirement is being pursued through the authority granted in FAR 52.211-6, Brand Name or Equal. This is a requirement for a Gatan, Inc. �BioQuantum K3 and associated accessories. � (vii)�� Period of Performance: �Delivery Within 18 Weeks ARO (viii)�� The provision at FAR clause 52.212-1, Instructions to Offerors � Commercial Items, applies to this acquisition. Mandatory Criteria�The camera must attach to our Gatan energy filter on the existing Krios cyroEM microscope. (ix)�� The provision at FAR clause 52.212-2, Evaluation � Commercial Items, is applicable. �Award will be made to the contractor providing the most advantageous quote to the Government. �Technical factors and price considered with technical factors outweighing price. � Specifically, the following technical factors will be evaluated: i.�� The vendor will be evaluated on their quoted product meeting the specifications under section 16.v 4.0 SALIENT / REQUIRED FEATURES AND SPECIFICATIONS. � (x)�� FAR clause 52.212-3, Offeror Representations and Certifications � Commercial Items, is applicable. �An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov If an offeror has not completed the annual representations and certifications electronically at the System for Award Management (SAM) website, the offeror shall complete only paragraphs (c) through (p) of this provision. � (xi)�� FAR clause at 52.212-4, Contract Terms and Conditions � Commercial Items, applies to this acquisition. (xii)�� FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders � Commercial Items, applies to this acquisition. �Including the following clauses and Prohibitions: i.�� 52.209-9, Updates of Publicly Available Information Regarding Responsibility Matters (Jul 2013) (41 U.S.C. 2313) ii.�� FAR 52.211-6, Brand Name or Equal. iii.�� 52.219-8, Utilization of Small Business Concerns (Oct 2014) (15 U.S.C. 637(d)(2) and (3)) iv.�� 52.219-28, Post Award Small Business Program Representation v.�� 52.222-19, Child Labor�Cooperation with Authorities and Remedies (Jan 2014) (E.O. 13126). vi.�� 52.222-21, Prohibition of Segregated Facilities vii.�� 52.222-26, Equal Opportunity viii.�� 52.222-35, Equal Opportunity for Veterans (Jul 2014) (38 U.S.C. 4212) ix.�� 52.222-36, Equal Opportunity for Workers with Disabilities x.�� 52.222-37, Employment Reports on Veterans (Jul 2014) (38 U.S.C. 4212) xi.�� 52.222-40, Notification of Employee Rights Under the National Labor Relations Act (Dec 2010) (E.O. 13496) xii.�� 52.222-50 Combating Trafficking in Persons xiii.�� 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving� xiv.�� 52.225-1, Buy American--Supplies (May 2014) (41 U.S.C. chapter 83) xv.�� 52.225-13, Restrictions on Certain Foreign Purchases Additional Clauses: i.�� 52.232-33, Payment by Electronic Funds Transfer� System for Award Management (Jul 2013) (31 U.S.C. 3332) (xiii)�� Additional Contract Requirements: None (xiv)�� The Defense Priorities and Allocations System (DPAS) and assigned rating are not applicable.� (xv)�� Offers shall be submitted via email to amber.harris@nih.gov (17)�� Place of Contract Performance:� �� National Institute of Health, NIDDK �� 8 Center Drive Bethesda, MD 20892 (18)�� Set-aside Status: This is not applicable to this requirement.
Web Link: SAM.gov Permalink
(https://beta.sam.gov/opp/49a1a40194e8446db38f9ff7e980d16e/view)
Place of Performance: Address: Bethesda, MD 20892, USA; Zip Code: 20892; Country: USA
Record: SN05693006-F 20200618/200616230209 (samdaily.us)
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65 -- High throughput High Quality Direct Detection Gatan K3